Novel enzymological profiles of human 11β-hydroxysteroid dehydrogenase type 1

Short-chain dehydrogenases/reductases (SDR)

1995 • 1,228 citations

11β-Hydroxysteroid Dehydrogenase

1997 • 725 citations

The Aldo-Keto Reductase Superfamily

1989 • 455 citations

A new nomenclature for the aldo-keto reductase superfamily

1997 • 350 citations

Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX‐2 inhibitor

1997 • 326 citations

11β-Hydroxysteroid Dehydrogenase

1993 • 189 citations

Mammalian Carbonyl Reductases

1980 • 173 citations

Expression of 11β-Hydroxysteroid Dehydrogenase Using Recombinant Vaccinia Virus

1990 • 158 citations

Reduction of drug ketones by dihydrodiol dehydrogenases, carbonyl reductase and aldehyde reductase of human liver

1995 • 154 citations

Xenobiotic carbonyl reduction and physiological steroid oxidoreduction

1995 • 138 citations

The 11β‐Hydroxysteroid Dehydrogenase System, A Determinant of Glucocorticoid and Mineralocorticoid Action

1997 • 108 citations

Molecular and structural aspects of xenobiotic carbonyl metabolizing enzymes. Role of reductases and dehydrogenases in xenobiotic phase I reactions

2000 • 106 citations

11 beta-hydroxysteroid dehydrogenase type 1 is a predominant 11 beta-reductase in the intact perfused rat liver

2000 • 86 citations

Selective inhibition of human type 1 11β‐hydroxysteroid dehydrogenase by synthetic steroids and xenobiotics

1998 • 61 citations

11Beta-hydroxysteroid dehydrogenase responsible for carbonyl reduction of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mouse lung microsomes.

1998 • 45 citations

7 11β-hydroxysteroid dehydrogenase

1994 • 41 citations

Purification and properties of a metyrapone-reducing enzyme from mouse liver microsomes—this ketone is reduced by an aldehyde reductase

1989 • 38 citations

[Biological behavior: serum levels, excretion and biotransformation of (3-benzoylphenyl)-2-propionic acid, or ketoprofen, in animals and men].

1973 • 35 citations

Ketoprofen (19.583 R.P.) (2-(3-benzoylphenyl)-propionic acid). Main pharmacological properties--outline of toxicological and pharmacokinetic data.

1976 • 31 citations

Human 11β-hydroxysteroid dehydrogenase 1/carbonyl reductase: recombinant expression in the yeast Pichia pastoris and Escherichia coli

2000 • 30 citations

The forms and functions of 11β-hydroxysteroid dehydrogenase

1993 • 29 citations

A study of the incidence of articular chondrocalcinosis in Paget's disease of bone.

1976 • 26 citations

Homologies between enzymes involved in steroid and xenobiotic carbonyl reduction in vertebrates, invertebrates and procaryonts

1992 • 20 citations

Oxidative bioactivation of the lactol prodrug of a lactone cyclooxygenase-2 inhibitor.

1999 • 16 citations

Identification and confirmation of 3-hydroxy metabolite of ketoprofen in camels by gas chromatography–mass spectrometry and nuclear magnetic resonance spectroscopy

1999 • 11 citations