Conversion of Dorsal from an activator to a repressor by the global corepressor Groucho

A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback

1989 • 2,555 citations

The ancient regulatory-protein family of WD-repeat proteins

1994 • 1,478 citations

Dorsoventral Patterning in Xenopus: Inhibition of Ventral Signals by Direct Binding of Chordin to BMP-4

1996 • 1,126 citations

Ssn6-Tup1 is a general repressor of transcription in yeast

1992 • 680 citations

Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins

1994 • 560 citations

Regulation of even-skipped stripe 2 in the Drosophila embryo.

1992 • 522 citations

decapentaplegic acts as a morphogen to organize dorsal-ventral pattern in the Drosophila embryo

1992 • 480 citations

Repression domain of the yeast global repressor Tup1 interacts directly with histones H3 and H4.

1996 • 460 citations

A conserved system for dorsal-ventral patterning in insects and vertebrates involving sog and chordin

1995 • 436 citations

rhomboid, a gene required for dorsoventral axis establishment and peripheral nervous system development in Drosophila melanogaster.

1990 • 389 citations

The WRPW Motif of the Hairy-Related Basic Helix-Loop-Helix Repressor Proteins Acts as a 4-Amino-Acid Transcription Repression and Protein-Protein Interaction Domain

1996 • 344 citations

The dorsal gradient morphogen regulates stripes of rhomboid expression in the presumptive neuroectoderm of the Drosophila embryo.

1992 • 324 citations

Binding affinities and cooperative interactions with bHLH activators delimit threshold responses to the dorsal gradient morphogen

1993 • 322 citations

Dorsal-ventral patterning of the Drosophila embryo depends on a putative negative growth factor encoded by the short gastrulation gene.

1994 • 307 citations

Molecular genetics of the single-minded locus: A gene involved in the development of the Drosophila nervous system

1988 • 254 citations

The dorsal morphogen is a sequence-specific DNA-binding protein that interacts with a long-range repression element in drosophila

1991 • 229 citations

An HMG-like protein that can switch a transcriptional activator to a repressor

1994 • 220 citations

The global transcriptional regulators, SSN6 and TUP1, play distinct roles in the establishment of a repressive chromatin structure.

1994 • 190 citations

The Drosophila short gastrulation gene prevents Dpp from autoactivating and suppressing neurogenesis in the neuroectoderm.

1996 • 178 citations

Transcriptional repression in development

1996 • 176 citations

Conversion of a dorsal-dependent silencer into an enhancer: evidence for dorsal corepressors.

1993 • 133 citations

The interplay between multiple enhancer and silencer elements defines the pattern of decapentaplegic expression.

1993 • 131 citations

Identification of genes required for alpha 2 repression in Saccharomyces cerevisiae.

1995 • 123 citations

Expression and Purification of Glutathione‐S‐Transferase Fusion Proteins

1994 • 121 citations

The torso response element binds GAGA and NTF-1/Elf-1, and regulates tailless by relief of repression.

1995 • 118 citations

SSNGenes That Affect Transcriptional Repression inSaccharomyces cerevisiaeEncode SIN4, ROX3, and SRB Proteins Associated with RNA Polymerase II

1996 • 117 citations

Individual dorsal morphogen binding sites mediate activation and repression in the Drosophila embryo.

1992 • 104 citations

hairy mediates dominant repression in the Drosophila embryo

1997 • 103 citations

Conversion of a silencer into an enhancer: evidence for a co-repressor in dorsal-mediated repression in Drosophila.

1993 • 100 citations

Binding sites for transcription factor NTF-1/Elf-1 contribute to the ventral repression of decapentaplegic.

1995 • 89 citations

Torso signalling regulates terminal patterning in Drosophila by antagonising Groucho-mediated repression

1997 • 84 citations

Interactions between dorsal and helix-loop-helix proteins initiate the differentiation of the embryonic mesoderm and neuroectoderm in Drosophila.

1993 • 80 citations

The same dorsal binding site mediates both activation and repression in a context-dependent manner.

1992 • 76 citations

The functional domains of the Drosophila morphogen dorsal: evidence from the analysis of mutants.

1992 • 71 citations

TLE expression correlates with mouse embryonic segmentation, neurogenesis, and epithelial determination

1995 • 68 citations

Regulation of the dorsal morphogen by the Toll and torso signaling pathways: a receptor tyrosine kinase selectively masks transcriptional repression.

1994 • 57 citations

A Direct Contact between the Dorsal rel Homology Domain and Twist May Mediate Transcriptional Synergy

1997 • 55 citations

The establishment and interpretation of transcription factor gradients in the Drosophila embryo

1995 • 35 citations