Recovery from ultraviolet‐induced growth arrest of primary rat hepatocytes by p53 antisense oligonucleotide treatment

Participation of p53 protein in the cellular response to DNA damage.

1991 • 3,818 citations

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1992 • 3,092 citations

p53 is required for radiation-induced apoptosis in mouse thymocytes

1993 • 2,911 citations

Thymocyte apoptosis induced by p53-dependent and independent pathways

1993 • 2,322 citations

Method for analysis of cellular DNA content of paraffin-embedded pathological material using flow cytometry.

1983 • 2,066 citations

Amplification of a gene encoding a p53-associated protein in human sarcomas

1992 • 1,959 citations

p53 function and dysfunction

1992 • 1,918 citations

Wild-type p53 is a cell cycle checkpoint determinant following irradiation.

1992 • 1,877 citations

Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form.

1990 • 978 citations

Assay for nanogram quantities of DNA in cellular homogenates

1979 • 923 citations

UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells.

1984 • 874 citations

Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells

1992 • 784 citations

The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle

1991 • 708 citations

High levels of p53 protein in UV-irradiated normal human skin.

1993 • 689 citations

DNA damage-inducible transcripts in mammalian cells.

1988 • 613 citations

Oligodeoxynucleotides as inhibitors of gene expression: a review.

1988 • 419 citations

Specific interaction between the p53 cellular tumour antigen and major heat shock proteins

1986 • 354 citations

Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2.

1990 • 353 citations

p53-mediated cell death: relationship to cell cycle control.

1993 • 339 citations

Regulation of Liver Growth: Protooncogenes and Transforming Growth Factors

1990 • 315 citations

Growth arrest induced by wild-type p53 protein blocks cells prior to or near the restriction point in late G1 phase.

1992 • 274 citations

p53-catalyzed annealing of complementary single-stranded nucleic acids.

1993 • 225 citations

Increases in sequence specific DNA binding by p53 following treatment with chemotherapeutic and DNA damaging agents.

1993 • 201 citations

Oligomerization of oncoprotein p53

1988 • 158 citations

Nuclear protein phosphorylation and growth control

1992 • 135 citations

Abrogation by c-myc of Gl phase arrest induced by RB protein but not by p53

1992 • 99 citations