GATA-6 Induces p21Cip1 Expression and G1Cell Cycle Arrest

The pathogenesis of atherosclerosis: a perspective for the 1990s

1993 • 10,730 citations

WAF1, a potential mediator of p53 tumor suppression

1993 • 8,360 citations

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1995 • 2,115 citations

Tumor spectrum analysis in p53-mutant mice

1994 • 2,034 citations

Correlation of Terminal Cell Cycle Arrest of Skeletal Muscle with Induction of p21 by MyoD

1995 • 1,154 citations

Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis.

1997 • 1,138 citations

GATA4 transcription factor is required for ventral morphogenesis and heart tube formation.

1997 • 1,031 citations

Genes specifically expressed at growth arrest of mammalian cells

1988 • 954 citations

Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937.

1996 • 922 citations

Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents.

1989 • 698 citations

Differential transcriptional activation by Oct-1 and Oct-2: Interdependent activation domains induce Oct-2 phosphorylation

1990 • 696 citations

Widespread long-term gene transfer to mouse skeletal muscles and heart.

1992 • 586 citations

GATA-4/5/6, a subfamily of three transcription factors transcribed in developing heart and gut.

1994 • 567 citations

Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiPl

1997 • 509 citations

Resistance to Apoptosis Conferred by Cdk Inhibitors During Myocyte Differentiation

1996 • 494 citations

The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth.

1994 • 484 citations

GATA-6: A Zinc Finger Transcription Factor That Is Expressed in Multiple Cell Lineages Derived from Lateral Mesoderm

1996 • 469 citations

p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts.

1991 • 455 citations

GATA transcription factors: key regulators of hematopoiesis.

1995 • 430 citations

CCAAT/enhancer-binding protein alpha (C/EBP alpha) inhibits cell proliferation through the p21 (WAF-1/CIP-1/SDI-1) protein.

1996 • 393 citations

Adenovirus-mediated over-expression of the cyclin/cyclin-dependent kinase inhibitor, p21 inhibits vascular smooth muscle cell proliferation and neointima formation in the rat carotid artery model of balloon angioplasty.

1995 • 363 citations

The growth arrest-specific gene, gas1, is involved in growth suppression

1992 • 274 citations

GATA-5: A Transcriptional Activator Expressed in a Novel Temporally and Spatially-Restricted Pattern during Embryonic Development

1997 • 253 citations

Arterial smooth muscle. A multifunctional mesenchymal cell.

1988 • 238 citations

Role of the p21 cyclin-dependent kinase inhibitor in limiting intimal cell proliferation in response to arterial injury.

1996 • 236 citations

CCAAT/Enhancer Binding Protein α Regulates p21 Protein and Hepatocyte Proliferation in Newborn Mice

1997 • 236 citations

TheXenopusGATA-4/5/6 Genes Are Associated with Cardiac Specification and Can Regulate Cardiac-Specific Transcription during Embryogenesis

1996 • 202 citations

Downregulation of cyclin-dependent kinase 2 activity and cyclin A promoter activity in vascular smooth muscle cells by p27(KIP1), an inhibitor of neointima formation in the rat carotid artery.

1997 • 192 citations

p21CIP1-mediated inhibition of cell proliferation by overexpression of the gax homeodomain gene.

1997 • 183 citations

The HumanGATA-6Gene: Structure, Chromosomal Location, and Regulation of Expression by Tissue-Specific and Mitogen-Responsive Signals

1996 • 144 citations

Molecular cloning of a diverged homeobox gene that is rapidly down-regulated during the G0/G1 transition in vascular smooth muscle cells.

1993 • 138 citations

Temporally and Spatially Coordinated Expression of Cell Cycle Regulatory Factors After Angioplasty

1997 • 131 citations

Vascular smooth muscle in culture

1987 • 129 citations

Regulated Expression of the Ets-1 Transcription Factor in Vascular Smooth Muscle Cells In Vivo and In Vitro

1996 • 93 citations

Expression of gax, a Growth Arrest Homeobox Gene, Is Rapidly Down-regulated in the Rat Carotid Artery during the Proliferative Response to Balloon Injury

1995 • 92 citations

Multiple growth factors are associated with lesions of atherosclerosis: Specificity or redundancy?

1996 • 62 citations

Gene Therapy for Head and Neck Cancer: Comparing the Tumor Suppressor Gene p53 and a Cell Cycle Regulator WAF1/CIP1 (p21)

1996 • 58 citations

Serum Induction of MEF2/RSRF Expression in Vascular Myocytes Is Mediated at the Level of Translation

1995 • 55 citations

The Gene for Transcription Factor GATA-6 Resides on Mouse Chromosome 18 and Is Expressed in Myocardium and Vascular Smooth Muscle

1996 • 53 citations

Opposite Regulation of Gax Homeobox Expression by Angiotensin II and C-Type Natriuretic Peptide

1997 • 36 citations

Influence of Animal Age on the Beta-Adrenergic System in Cultured Rat Aortic and Mesenteric Artery Smooth Muscle Cells

1992 • 31 citations

Mitogen-responsive nuclear factors that mediate growth control signals in vascular myocytes

1995 • 27 citations

Structures and chromosome locations of the human MEF2A gene and a pseudogene MEF2AP

1996 • 16 citations

Rapid characterization of growth-arrest genes in transient transfection assays.

1995 • 15 citations