Calcium-Antagonist Drugs

Different modes of Ca channel gating behaviour favoured by dihydropyridine Ca agonists and antagonists

1984 • 1,292 citations

Cerebral Arterial Spasm – A Controlled Trial of Nimodipine in Patients with Subarachnoid Hemorrhage

1983 • 1,148 citations

Novel dihydropyridines with positive inotropic action through activation of Ca2+ channels

1983 • 1,010 citations

GABA‐Benzodiazepine‐Barbiturate Receptor Interactions

1981 • 910 citations

Comparative pharmacology of calcium antagonists: Nifedipine, verapamil and diltiazem

1980 • 865 citations

Calcium Channel Blocking Agents in the Treatment of Cardiovascular Disorders. Part II: Hemodynamic Effects and Clinical Applications

1980 • 551 citations

Mechanisms of Calcium Antagonist-Induced Vasodilation

1983 • 370 citations

Calcium Channel Blocking Agents in the Treatment of Cardiovascular Disorders. Part I: Basic and Clinical Electrophysiologic Effects

1980 • 332 citations

Dihydropyridine derivatives prolong the open state of Ca channels in cultured cardiac cells.

1984 • 323 citations

Characterization of binding of the Ca++ channel antagonist, [3H]nitrendipine, to guinea-pig ileal smooth muscle.

1983 • 292 citations

Drug and Neurotransmitter Receptors in the Brain

1984 • 274 citations

Dihydropyridine BAY-K-8644 activates chromaffin cell calcium channels

1984 • 270 citations

[3H]nitrendipine-labeled calcium channels discriminate inorganic calcium agonists and antagonists.

1982 • 265 citations

Phosphorylation of the calcium antagonist receptor of the voltage-sensitive calcium channel by cAMP-dependent protein kinase.

1985 • 253 citations

A functional correlate for the dihydropyridine binding site in rat brain

1985 • 253 citations

Are dihydropyridine binding sites voltage sensitive calcium channels?

1984 • 234 citations

The binding of [3H]nitrendipine to receptors for calcium channel antagonists in the heart, cerebral cortex, and ileum of rats

1982 • 227 citations

Antischizophrenic drugs of the diphenylbutylpiperidine type act as calcium channel antagonists.

1983 • 219 citations

Calcium channels in rat brain synaptosomes: identification and pharmacological characterization. High affinity blockade by organic Ca2+ channel blockers

1985 • 218 citations

A unitary mechanism of calcium antagonist drug action.

1983 • 214 citations

Pimozide

1976 • 191 citations

1,4‐Dihydropyridine Ca²⁺ channel antagonists and activators: A comparison of binding characteristics with pharmacology

1984 • 182 citations

Treatment of premature labor with the calcium antagonist nifedipine

1980 • 182 citations

Dopamine receptors, neuroleptics, and schizophrenia

1981 • 171 citations

Specific binding of [3H]nitrendipine to membranes from coronary arteries and heart in relation to pharmacological effects. Paradoxical stimulation by diltiazem

1982 • 158 citations

Calcium antagonist binding sites in the rat brain: Quantitative autoradiographic mapping using the 1,4-dihydropyridines [3H]PN 200-110 and [3H]PY 108-068

1984 • 148 citations

Slow inward calcium currents have no obvious role in muscle excitation–contraction coupling

1982 • 147 citations

⁴⁵Ca²⁺ Uptake into Rat Whole Brain Synaptosomes Unaltered by Dihydropyridine Calcium Antagonists

1983 • 137 citations

Loperamide: blockade of calcium channels as a mechanism for antidiarrheal effects.

1984 • 136 citations

The Glycine Synaptic Receptor: Evidence That Strychnine Binding Is Associated with the Ionic Conductance Mechanism

1974 • 136 citations

Evidence for multiple receptor sites within the putative calcium channel

1982 • 134 citations

Nimodipine, a New Calcium Antagonist, in the Prophylactic Treatment of Migraine

1983 • 127 citations

Calcium antagonists: A new class of drugs

1983 • 125 citations

Effects of Nifedipine on the Smooth Muscle of the Human Urinary Tract in Vitro and in Vivo

1978 • 112 citations

Antihypertensive and renal effects of orally administered verapamil

1980 • 111 citations

Flunarizine, a Calcium Channel Blocker: a New Prophylactic Drug in Migraine

1983 • 106 citations

Verapamil in prophylactic therapy of migraine

1984 • 98 citations

Autoradiographic visualization of [3H]nitrendipine binding sites in rat brain: Localization to synaptic zones

1982 • 98 citations

Diltiazem enhancement of [3H]nitrendipine binding to calcium channel associated drug receptor sites in rat brain synaptosomes

1982 • 97 citations

Temperature‐dependent regulation of d‐cis‐[³H]diltiazem binding to Ca²⁺ channels by 1,4‐dihydropyridine channel agonists and antagonists

1983 • 96 citations

Autoradiographic localization of calcium channel antagonist receptors in rat brain with [3H]nitrendipine

1985 • 90 citations

Role of nifedipine in treatment of hypertension.

1983 • 86 citations

(?)-3H-desmethoxyverapamil labelling of putative calcium channels in brain: autoradiographic distribution and allosteric coupling to 1,4-dihydropyridine and diltiazem binding sites

1984 • 84 citations

Psychotropic drug side effects : clinical and theoretical perspectives

1970 • 79 citations

[3H] verapamil binding sites in skeletal muscle tranverse tubule membranes

1984 • 64 citations

Target size analysis and molecular properties of Ca²⁺ channels labelled with [³H]verapamil

1984 • 62 citations

(—)‐[³H]Desmethoxyverapamil, a novel Ca²⁺ channel probe

1984 • 60 citations

Effects of verapamil, diltiazem and ryosidine on the release of dopamine and acetylcholine in rabbit caudate nucleus slices

1984 • 59 citations

Controlled double-blind trial of dazoxiben and nifedipine in the treatment of Raynaud's phenomenon

1984 • 57 citations

Calcium channel blockade: possible explanation for thioridazine's peripheral side effects

1984 • 51 citations

Aequorin measurements of free calcium in single mammalian cells

1983 • 48 citations

Diltiazem potentiates the negative inotropic action of nimodipine in heart

1983 • 48 citations

Diltiazem in the Treatment of Mild or Moderate Essential Hypertension. Comparison with Metoprolol in a Crossover Double‐Blind Trial

1984 • 45 citations

[3H]verapamil binding sites in brain and skeletal muscle: Regulation by calcium

1983 • 45 citations

A controlled study of penfluridol in the treatment of chronic schizophrenia

1978 • 36 citations

Qualitative measurements of cytosolic calcium ion concentration within isolated Guinea pig nerve endings using entrapped arsenazo III

1983 • 34 citations

Verapamil: Full spectrum calcium channel blocking agent: An overview

1984 • 31 citations

Use of Nifedipine as an Adjunct to Current Antihypertensive Therapy

1984 • 26 citations

Evaluation of calcium entry blockers in several models of immediate hypersensitivity.

1984 • 24 citations

Pharmacological Inhibition of Uterine Activity

1982 • 20 citations

Blockade of Ca²⁺ channels inhibits K⁺ contractures but not twitches in skeletal muscle

1984 • 20 citations

The influence of resting membrane potential on the effect of verapamil on atria

1980 • 15 citations

Calcium Antagonists in the Treatment of Individuals with Ischemic Heart Disease

1982 • 14 citations

Diltiazem-like effect of thioridazine on the dihydropyridine binding site of the calcium channel of rat myocardial membranes

1984 • 10 citations

Effects of loperamide on the guinea pig taenia coli

1979 • 10 citations

Mechanisms involved in the blocking effects of pimozide on smooth muscle contraction

1983 • 3 citations