Interindividual Differences in Hepatic Expression of CYP3A4: Relationship to Genetic Polymorphism in the 5′-Upstream Regulatory Region

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

1994 • 2,716 citations

Cytochrome P-450: Structure, Mechanism, and Biochemistry

1986 • 2,703 citations

Cytochrome P450: Structure, mechanism, and biochemistry

1996 • 1,502 citations

SXR, a novel steroid and xenobioticsensing nuclear receptor

1998 • 903 citations

Identification of a human nuclear receptor defines a new signaling pathway for CYP 3 A induction

1998 • 852 citations

Use of In Vitro and In Vivo Data to Estimate the Likelihood of Metabolic Pharmacokinetic Interactions

1997 • 755 citations

ENZYME-STRUCTURE RELATIONSHIPS IN THE ENDOPLASMIC RETICULUM OF RAT LIVER

1962 • 718 citations

RESPONSE: Re: Modification of Clinical Presentation of Prostate Tumors by a Novel Genetic Variant in CYP3A4

1999 • 478 citations

Human liver microsomal steroid metabolism: Identification of the major microsomal steroid hormone 6β-hydroxylase cytochrome P-450 enzyme

1988 • 413 citations

Modification of Clinical Presentation of Prostate Tumors by a Novel Genetic Variant in CYP3A4

1998 • 348 citations

Steroid hormone hydroxylase specificities of eleven cDNA-expressed human cytochrome P450s

1991 • 326 citations

Association of CYP 3 A 4 genotype with treatment-related leukemia

1998 • 315 citations

Gene structure of CYP3A4, an adult‐specific form of cytochrome P450 in human livers, and its transcriptional control

1993 • 208 citations

Major pathway of imipramine metabolism is catalyzed by cytochromes P-450 1A2 and P-450 3A4 in human liver.

1993 • 168 citations

Identification of the rabbit and human cytochromes P-450IIIA as the major enzymes involved in the N-demethylation of diltiazem.

1990 • 158 citations

A position-dependent silencer plays a major role in repressing alpha-fetoprotein expression in human hepatoma.

1991 • 125 citations

Interindividual variability in catalytic activity and immunoreactivity of three major human liver cytochrome P450 isozymes

1996 • 81 citations

A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 genein vitro

1999 • 74 citations

Human liver microsomal cytochrome P-450IIE1. Imnunological evaluation of its contribution to microsomal ethanol oxidation, carboti tetrachloride reduction and NADPH oxidase activity

1989 • 71 citations

Case report of a Thai male cystic fibrosis patinet with the 1898+ 1G-->T splicing mutation in the CFTR gene: a review of East Asian cases. Mutations in brief no. 196. Online.

1998 • 30 citations

Induction of CYP1A1 by GABA Receptor Ligands

1996 • 14 citations