Site-specific alterations in the B oligomer that affect receptor-binding activities and mitogenicity of pertussis toxin.

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

A Broad Host Range Mobilization System for In Vivo Genetic Engineering: Transposon Mutagenesis in Gram Negative Bacteria

1983 • 7,336 citations

Construction of a broad host range cosmid cloning vector and its use in the genetic analysis of Rhizobium mutants

1982 • 857 citations

A Simple Chemically Defined Medium for the Production of Phase I Bordetella pertussis

1970 • 637 citations

Subunit structure of islet-activating protein, pertussis toxin, in conformity with the A-B model

1982 • 497 citations

Virulence Factors of Bordetella Pertussis

1986 • 436 citations

DEVELOPMENT OF A PERTUSSIS COMPONENT VACCINE IN JAPAN

1984 • 417 citations

Pertussis Toxin Gene: Nucleotide Sequence and Genetic Organization

1986 • 364 citations

Cloning and sequencing of the pertussis toxin genes: operon structure and gene duplication.

1986 • 343 citations

Mutants of Pertussis Toxin Suitable for Vaccine Development

1989 • 318 citations

Induction of a novel morphological response in Chinese hamster ovary cells by pertussis toxin

1983 • 251 citations

A role of the B-oligomer moiety of islet-activating protein, pertussis toxin, in development of the biological effects on intact cells.

1983 • 227 citations

Biological activities of crystalline pertussigen from Bordetella pertussis

1981 • 226 citations

Pertussis toxin has eukaryotic-like carbohydrate recognition domains.

1992 • 143 citations

Mouse-protecting and histamine-sensitizing activities of pertussigen and fimbrial hemagglutinin from Bordetella pertussis

1981 • 131 citations

Binding of pertussis toxin to eucaryotic cells and glycoproteins

1989 • 119 citations

Recombinant interleukin 2 as an adjuvant for vaccine-induced protection. Immunization of guinea pigs with herpes simplex virus subunit vaccines.

1988 • 114 citations

Lectin-like binding of pertussis toxin to a 165-kilodalton Chinese hamster ovary cell glycoprotein.

1988 • 113 citations

Pertussis Toxin S1 Mutant with Reduced Enzyme Activity and a Conserved Protective Epitope

1988 • 113 citations

The recognition event between virus and host cell receptor: a target for antiviral agents

1990 • 109 citations

Subunit S1 of pertussis toxin: mapping of the regions essential for ADP-ribosyltransferase activity.

1988 • 105 citations

Roles of the disulfide bond and the carboxy-terminal region of the S1 subunit in the assembly and biosynthesis of pertussis toxin

1990 • 99 citations

Protective activities in mice of monoclonal antibodies against pertussis toxin

1990 • 73 citations

Molecular cloning of pertussis toxin genes

1986 • 66 citations

ADP-ribosyltransferase mutations in the catalytic S-1 subunit of pertussis toxin

1988 • 61 citations

Activities of complete and truncated forms of pertussis toxin subunits S1 and S2 synthesized by Escherichia coli

1987 • 57 citations

Use of glycosyltransferases to restore pertussis toxin receptor activity to asialoagalactofetuin.

1988 • 55 citations

Pertussis toxin is required for pertussis vaccine encephalopathy.

1985 • 51 citations

Development of an acellular pertussis vaccine and its administration as a booster in healthy adults

1991 • 48 citations

Engineering of genetically detoxified pertussis toxin analogs for development of a recombinant whooping cough vaccine

1990 • 48 citations

Identification of amino acid residues essential for the enzymatic activities of pertussis toxin.

1989 • 43 citations

Pertussis toxin analog with reduced enzymatic and biological activities is a protective immunogen

1990 • 34 citations

Structure-function relationship of islet-activating protein pertussis toxin: biological activities of hybrid toxins reconstituted from native and methylated subunits

1986 • 30 citations

Lymphocyte receptors for pertussis toxin

1990 • 29 citations

The role of cysteine 41 in the enzymatic activities of the pertussis toxin S1 subunit as investigated by site-directed mutagenesis.

1990 • 29 citations

Maintenance of biological activity of pertussis toxin radioiodinated while bound to fetuin-agarose

1987 • 24 citations

Monoclonal antibodies that define neutralizing epitopes of pertussis toxin: conformational dependence and epitope mapping

1989 • 24 citations

Studies on the optimal conditions for inactivation of Bordetella pertussis organisms with glutaraldehyde for preparation of a safe and potent pertussis vaccine

1988 • 15 citations

Characterization of murine monoclonal antibodies that recognize defined epitopes of pertussis toxin and neutralize its toxic effect on Chinese hamster ovary cells

1991 • 14 citations

Monoclonal antibodies specific for pertussis toxin subunits and identification of the haptoglobin-binding site.

1989 • 12 citations

An Escherichia coli insertion element (IS2) provides a functional promoter in Bordetella pertussis

1991 • 6 citations

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