Dimerization inhibits the activity of receptor-like protein-tyrosine phosphatase-α

Protein kinases and phosphatases: The Yin and Yang of protein phosphorylation and signaling

1995 • 2,907 citations

The pCL vector system: rapid production of helper-free, high-titer, recombinant retroviruses

1996 • 728 citations

From Form to Function: Signaling by Protein Tyrosine Phosphatases

1996 • 526 citations

Isolation of monoclonal antibodies that recognize the transforming proteins of avian sarcoma viruses

1983 • 518 citations

Cell transformation and activation of pp60c-src by overexpression of a protein tyrosine phosphatase

1992 • 455 citations

Switching Signals On or Off by Receptor Dimerization

1998 • 428 citations

Structural basis for inhibition of receptor protein-tyrosine phosphatase-α by dimerization

1996 • 324 citations

Ligand-mediated negative regulation of a chimeric transmembrane receptor tyrosine phosphatase

1993 • 288 citations

Receptor protein tyrosine phosphatase α activates Src-family kinases and controls integrin-mediated responses in fibroblasts

1999 • 273 citations

Dimerization-Induced Inhibition of Receptor Protein Tyrosine Phosphatase Function Through an Inhibitory Wedge

1998 • 268 citations

Receptor protein tyrosine phosphatase alpha activates pp60c-src and is involved in neuronal differentiation.

1993 • 237 citations

Targeted disruption of the tyrosine phosphatase PTPα leads to constitutive downregulation of the kinases Src and Fyn

1999 • 207 citations

Cloning and expression of a widely expressed receptor tyrosine phosphatase.

1990 • 180 citations

Crystal Structure of the Tandem Phosphatase Domains of RPTP LAR

1999 • 174 citations

Protein-tyrosine Phosphatase α Regulates Src Family Kinases and Alters Cell-Substratum Adhesion

1998 • 137 citations

The Crystal Structure of Domain 1 of Receptor Protein-tyrosine Phosphatase μ

1997 • 115 citations

Activation of Neu (ErbB-2) Mediated by Disulfide Bond-Induced Dimerization Reveals a Receptor Tyrosine Kinase Dimer Interface

1998 • 105 citations

Stabilization of an active dimeric form of the epidermal growth factor receptor by introduction of an inter-receptor disulfide bond

1994 • 102 citations

The Second Catalytic Domain of Protein Tyrosine Phosphatase δ (PTPδ) Binds to and Inhibits the First Catalytic Domain of PTPς

1998 • 102 citations

Tight association of GRB2 with receptor protein-tyrosine phosphatase alpha is mediated by the SH2 and C-terminal SH3 domains.

1996 • 87 citations

A New Monoclonal Antibody Which Selectively Recognizes the Active Form of Src Tyrosine Kinase

1996 • 87 citations

Characterization of Recombinant CD45 Cytoplasmic Domain Proteins

1998 • 86 citations

Evidence for monomeric and dimeric forms of CD45 associated with a 30-kDa phosphorylated protein.

1992 • 85 citations

The Receptor-like Protein-tyrosine Phosphatase, RPTPα, Is Phosphorylated by Protein Kinase C on Two Serines Close to the Inner Face of the Plasma Membrane

1995 • 78 citations

Stimulation of receptor protein-tyrosine phosphatase alpha activity and phosphorylation by phorbol ester.

1995 • 65 citations

Comparative Kinetic Analysis and Substrate Specificity of the Tandem Catalytic Domains of the Receptor-like Protein-tyrosine Phosphatase α

1997 • 61 citations

Streptavidin blotting: a sensitive technique to study cell surface proteins; application to investigate autophosphorylation and endocytosis of biotin-labeled insulin receptors.

1993 • 54 citations

An extra cysteine proximal to the transmembrane domain induces differential cross-linking of p185neu and p185neu.

1992 • 29 citations