Evidence for monomeric and dimeric forms of CD45 associated with a 30-kDa phosphorylated protein.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Quantitative Film Detection of 3H and 14C in Polyacrylamide Gels by Fluorography

1975 • 4,693 citations

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1984 • 2,762 citations

Diversity of G Proteins in Signal Transduction

1991 • 1,990 citations

GROWTH FACTOR RECEPTOR TYROSINE KINASES

1988 • 1,841 citations

A thousand and one protein kinases

1987 • 1,066 citations

Protein Tyrosine Phosphatases: A Diverse Family of Intracellular and Transmembrane Enzymes

1991 • 973 citations

The Cellular Functions of Small GTP-Binding Proteins

1990 • 881 citations

Roles of G protein subunits in transmembrane signalling

1988 • 794 citations

Signal Transduction by the Platelet-Derived Growth Factor Receptor

1989 • 653 citations

Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens

1978 • 589 citations

Evidence that the leukocyte-common antigen is required for antigen-induced T lymphocyte proliferation

1989 • 509 citations

Chemical probes of extended biological structures: Synthesis and properties of the cleavable protein cross-linking reagent [35S]dithiobis(succinimidyl propionate)

1976 • 493 citations

Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyl inositol pathway

1990 • 466 citations

Expression of CD45 alters phosphorylation of the lck-encoded tyrosine protein kinase in murine lymphoma T-cell lines.

1989 • 465 citations

T cell antigen receptor activation pathways: The tyrosine kinase connection

1991 • 442 citations

Demonstration that the leukocyte common antigen (CD45) is a protein tyrosine phosphatase

1988 • 425 citations

Rapid activation of the T-cell tyrosine protein kinase pp56lck by the CD45 phosphotyrosine phosphatase.

1989 • 425 citations

Allosteric regulation of the epidermal growth factor receptor kinase.

1986 • 381 citations

Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production.

1991 • 349 citations

The B lymphocyte adhesion molecule CD22 interacts with leukocyte common antigen CD45RO on T cells and α2–6 sialyltransferase, CD75, on B cells

1991 • 348 citations

A family of receptor-linked protein tyrosine phosphatases in humans and Drosophila.

1989 • 303 citations

Interspecies spleen-myeloma hybrid producing monoclonal antibodies against mouse lymphocyte surface glycoprotein, T200.

1978 • 282 citations

A new member of the immunoglobulin superfamily that has a cytoplasmic region homologous to the leukocyte common antigen.

1988 • 277 citations

Progressive Loss of H-2 Antigens With Concomitant Increase of Cell-Surface Antigen(s) Determined by Moloney Leukemia Virus in Cultured Murine Lymphomas23

1973 • 239 citations

CD45 regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T or B cells.

1988 • 223 citations

Cloned T Lymphocytes and Monoclonal Antibodies as Probes for Cell Surface Molecules Active in T Cell‐Mediated Cytolysis

1982 • 219 citations

Binding properties of a cell adhesion molecule from neural tissue.

1982 • 214 citations

Coassociation of CD26 (dipeptidyl peptidase IV) with CD45 on the surface of human T lymphocytes.

1991 • 208 citations

Receptor protein-tyrosine phosphatase gamma is a candidate tumor suppressor gene at human chromosome region 3p21.

1991 • 207 citations

CD45, an integral membrane protein tyrosine phosphatase. Characterization of enzyme activity.

1990 • 163 citations

Coclustering CD45 with CD4 or CD8 alters the phosphorylation and kinase activity of p56lck.

1990 • 142 citations

Association of CD2 and CD45 on human T lymphocytes

1990 • 139 citations

A T-lymphoma transmembrane glycoprotein (gp180) is linked to the cytoskeletal protein, fodrin.

1985 • 119 citations

Intimate association of Thy-1 and the T-cell antigen receptor with the CD45 tyrosine phosphatase.

1990 • 116 citations

Expression of transferrin receptor on murine hematopoietic progenitors

1984 • 112 citations

Negative Regulation of CD45 Protein Tyrosine Phosphatase Activity by Ionomycin in T Cells

1991 • 108 citations

B-cell variant of mouse T200 (Ly-5): evidence for alternative mRNA splicing.

1987 • 105 citations

A functional complex is formed in human T lymphocytes between the protein tyrosine phosphatase CD45, the protein tyrosine kinase p56^lck and pp³², a possible common substrate

1991 • 104 citations

Reaction of dimethyl-3,3'-dithiobispropionimidate with intact human erythrocytes. Cross-linking of membrane proteins and hemoglobin

1975 • 103 citations

Leukocyte cell surface enzymology: CD45 (LCA, T200) is a protein tyrosine phosphatase

1989 • 99 citations

Protein-tyrosine-phosphatase CD45 is phosphorylated transiently on tyrosine upon activation of Jurkat T cells.

1991 • 90 citations

Activation of tyrosine phosphorylation in human T cells via the CD2 pathway. Regulation by the CD45 tyrosine phosphatase.

1990 • 87 citations

CD45-protein tyrosine phosphatase cross-linking inhibits T cell receptor CD3-mediated activation in human T cells.

1989 • 85 citations

Disposition of T200 glycoprotein in the plasma membrane of a murine lymphoma cell line.

1980 • 79 citations

CD45 cross-linking regulates phospholipase C activation and tyrosine phosphorylation of specific substrates in CD3/Ti-stimulated T cells.

1991 • 74 citations

Sequences of Ly-5 cDNA: isoform-related diversity of Ly-5 mRNA.

1986 • 74 citations

Isolation of membrane associated immunoglobulins from T lymphocytes by non-ionic detergents

1976 • 69 citations

A 32-kD GTP-Binding Protein Associated with the CD4-p56^lckand CD8-p56^lckT Cell Receptor Complexes

1991 • 61 citations

Acquisition of the functional properties of the transferrin receptor during its biosynthesis

1991 • 16 citations