Genetic Dissection of the Drosophila Cubitus interruptus Signaling Complex

Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

1998 • 1,740 citations

Compartment boundaries and the control of Drosopfiffa limb pattern by hedgehog protein

1994 • 842 citations

Leptomycin B Inhibition of Signal-Mediated Nuclear Export by Direct Binding to CRM1

1998 • 801 citations

Developmental Compartmentalisation of the Wing Disk of Drosophila

1973 • 770 citations

Proteolysis That Is Inhibited by Hedgehog Targets Cubitus interruptus Protein to the Nucleus and Converts It to a Repressor

1997 • 658 citations

Mammalian Suppressor-of-Fused modulates nuclear–cytoplasmic shuttling of GLI-1

1999 • 454 citations

Role of the Drosophila patched gene in positional signalling

1991 • 414 citations

Compartments and Polyclones in Insect Development

1975 • 380 citations

Hedgehog Controls Limb Development by Regulating the Activities of Distinct Transcriptional Activator and Repressor Forms of Cubitus interruptus

1999 • 374 citations

Hedgehog Elicits Signal Transduction by Means of a Large Complex Containing the Kinesin-Related Protein Costal2

1997 • 371 citations

Costal2, a Novel Kinesin-Related Protein in the Hedgehog Signaling Pathway

1997 • 329 citations

Sending and Receiving the Hedgehog Signal: Control by the Drosophila Gli Protein Cubitus interruptus

1996 • 320 citations

Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator

1998 • 303 citations

The Drosophila cubitus interruptus protein and its role in the wingless and hedgehog signal transduction pathways

1995 • 275 citations

Nuclear Trafficking of Cubitus interruptus in the Transcriptional Regulation of Hedgehog Target Gene Expression

1999 • 262 citations

Gli proteins and Hedgehog signaling: development and cancer

1999 • 249 citations

Mouse Suppressor of fused is a negative regulator of Sonic hedgehog signaling and alters the subcellular distribution of Gli1

1999 • 203 citations

Suppressor of Fused opposes Hedgehog signal transduction by impeding nuclear accumulation of the activator form of Cubitus interruptus

2000 • 197 citations

Characterization of the human Suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli

1999 • 184 citations

Interactions with Costal2 and Suppressor of fused regulate nuclear translocation and activity of Cubitus interruptus

2000 • 180 citations

In vivo evidence that Patched and Smoothened constitute distinct binding and transducing components of a Hedgehog receptor complex

1998 • 173 citations

Protein kinase A directly regulates the activity and proteolysis of cubitus interruptus

1998 • 169 citations

The COE transcription factor Collier is a mediator of short-range Hedgehog-induced patterning of the Drosophila wing

1999 • 164 citations

Proteolysis of Cubitus interruptus in Drosophila requires phosphorylation by Protein Kinase A

1999 • 159 citations

Suppressor of fused links Fused and Cubitus interruptus on the Hedgehog signalling pathway

1998 • 155 citations

Drosophila cubitus interruptus forms a negative feedback loop with patched and regulates expression of Hedgehog target genes

1997 • 140 citations

Gli regulation by the opposing activities of Fused and Suppressor of Fused

2000 • 137 citations

The subcellular localization and activity of Drosophila Cubitus interruptus are regulated at multiple levels

1999 • 135 citations

engrailedexpression in the anterior lineage compartment of the developing wing blade ofDrosophila

1992 • 134 citations

Characterization of Suppressor of fused, a complete suppressor of the fused segment polarity gene of Drosophila melanogaster.

1992 • 130 citations

Nuclear import of Cubitus interruptus is regulated by Hedgehog via a mechanism distinct from Ci stabilization and Ci activation

2000 • 118 citations

Identification of a Tetrameric Hedgehog Signaling Complex

2000 • 111 citations

Modulation of Hedgehog target gene expression by the Fused serine–threonine kinase in wing imaginal discs

1998 • 102 citations

Segmental polarity in Drosophila melanogaster: genetic dissection of fused in a Suppressor of fused background reveals interaction with costal-2.

1993 • 85 citations

Functional Domains of Fused, a Serine-Threonine Kinase Required for Signaling in Drosophila

1996 • 52 citations

Expression of the Drosophila gooseberry Locus Defines a Subset of Neuroblast Lineages in the Central Nervous System

1995 • 50 citations

Cubitus interruptus is necessary but not sufficient for direct activation of a wing-specific decapentaplegic enhancer

1999 • 48 citations