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Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease.

2001 • 516 citations

β-Amyloid Activates the Mitogen-Activated Protein Kinase Cascade via Hippocampal α7 Nicotinic Acetylcholine Receptors:In VitroandIn VivoMechanisms Related to Alzheimer's Disease

2001 • 446 citations

Neurochemistry and pharmacology of the major hippocampal transmitter systems: Synaptic and nonsynaptic interactions

1998 • 362 citations

Assembly of Human Neuronal Nicotinic Receptor α5 Subunits with α3, β2, and β4 Subunits

1996 • 338 citations

Galantamine Is an Allosterically Potentiating Ligand of Neuronal Nicotinic but Not of Muscarinic Acetylcholine Receptors

2003 • 325 citations

Nicotinic Stimulation Produces Multiple Forms of Increased Glutamatergic Synaptic Transmission

1998 • 274 citations

Release of [³H]‐noradrenaline from rat hippocampal synaptosomes by nicotine: mediation by different nicotinic receptor subtypes from striatal [³H]‐dopamine release

1996 • 263 citations

Characterisation of the binding of [3H]methyllycaconitine: a new radioligand for labelling α7-type neuronal nicotinic acetylcholine receptors

1999 • 249 citations

Noradrenergic Regulation of Synaptic Plasticity in the Hippocampal CA1 Region

1997 • 235 citations

Agonist responses of neuronal nicotinic acetylcholine receptors are potentiated by a novel class of allosterically acting ligands.

1996 • 222 citations

Human alpha 7 acetylcholine receptor: cloning of the alpha 7 subunit from the SH-SY5Y cell line and determination of pharmacological properties of native receptors and functional alpha 7 homomers expressed in Xenopus oocytes.

1994 • 210 citations

Unconventional ligands and modulators of nicotinic receptors

2002 • 204 citations

Nicotine activates the extracellular signal‐regulated kinase 1/2 via the α7 nicotinic acetylcholine receptor and protein kinase A, in SH‐SY5Y cells and hippocampal neurones

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Characterization of Nicotinic Acetylcholine Receptors Expressed by Cells of the SH-SY5Y Human Neuroblastoma Clonal Line

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The Nicotinic Allosteric Potentiating Ligand Galantamine Facilitates Synaptic Transmission in the Mammalian Central Nervous System

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UB-165: A Novel Nicotinic Agonist with Subtype Selectivity Implicates the α4β2* Subtype in the Modulation of Dopamine Release from Rat Striatal Synaptosomes

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Host Cell‐Specific Folding and Assembly of the Neuronal Nicotinic Acetylcholine Receptor α7 Subunit

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The reversible cholinesterase inhibitor physostigmine has channel-blocking and agonist effects on the acetylcholine receptor-ion channel complex.

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Pharmacological characterization of neuronal acetylcholine gated ion channel receptor-mediated hippocampal norepinephrine and striatal dopamine release from rat brain slices.

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Synaptic-type acetylcholine receptors raise intracellular calcium levels in neurons by two mechanisms

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Identification and functional characterization of a new agonist site on nicotinic acetylcholine receptors of cultured hippocampal neurons.

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Allosterically potentiating ligands of nicotinic receptors as a treatment strategy for Alzheimer’s disease

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Physostigmine, galanthamine and codeine act as ‘noncompetitive nicotinic receptor agonists’ on clonal rat pheochromocytoma cells

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A double life: cytosolic aconitase as a regulatory RNA binding protein.

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Pharmacological characterization of a nicotinic autoreceptor in rat hippocampal synaptosomes

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Physostigmine and galanthamine: probes for a novel binding site on the alpha 4 beta 2 subtype of neuronal nicotinic acetylcholine receptors stably expressed in fibroblast cells.

1994 • 103 citations

Neurochemical Studies of Alzheimer's Disease

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Up-regulation of Cell-surface α4β2 Neuronal Nicotinic Receptors by Lower Temperature and Expression of Chimeric Subunits

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Interaction of 9-amino-1,2,3,4-tetrahydroaminoacridine (THA) with human cortical nicotinic and muscarinic receptor binding in vitro

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Nicotine‐evoked transmitter release from synaptosomes: functional association of specific presynaptic acetylcholine receptors and voltage‐gated calcium channels

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Nicotinic Cholinergic Modulation: Galantamine as a Prototype

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Competitive Potentiation of Acetylcholine Effects on Neuronal Nicotinic Receptors by Acetylcholinesterase‐Inhibiting Drugs

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Differential effects of chronic drug treatment on α3^* and α7 nicotinic receptor binding sites, in hippocampal neurones and SH‐SY5Y cells

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Synthesis and Pharmacological Characterization of Novel Analogues of the Nicotinic Acetylcholine Receptor Agonist (±)-UB-165

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Functional role of laminin carbohydrate.

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Assessment of nicotinic acetylcholine receptor-mediated release of [3H]-norepinephrine from rat brain slices using a new 96-well format assay

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Effects of chronic drug treatments on increases in intracellular calcium mediated by nicotinic acetylcholine receptors in SH‐SY5Y cells

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Pharmacology of the nicotinic acetylcholine receptor from fetal rat muscle expressed in Xenopus oocytes

1996 • 36 citations

Nicotinic acetylcholine receptor-mediated release of [3H]norepinephrine from developing and adult rat hippocampus: direct and indirect mechanisms

2002 • 33 citations

The Role of Nicotinic Acetylcholine Receptors in Cognitive Function

2000 • 12 citations

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