Linkage of M-CSF Signaling to Mitf, TFE3, and the Osteoclast Defect in Mitfmi/mi Mice

Bone Resorption by Osteoclasts

2000 • 3,797 citations

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

1991 • 2,028 citations

The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene

1990 • 1,763 citations

Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand

1999 • 1,621 citations

RANK is essential for osteoclast and lymph node development

1999 • 1,417 citations

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

1999 • 1,267 citations

c-Fos: a Key Regulator of Osteoclast-Macrophage Lineage Determination and Bone Remodeling

1994 • 1,253 citations

Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities.

1996 • 1,115 citations

Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein

1993 • 1,083 citations

Total absence of colony-stimulating factor 1 in the macrophage-deficient osteopetrotic (op/op) mouse.

1990 • 1,012 citations

Requirement for NF-κB in osteoclast and B-cell development

1997 • 994 citations

Mice lacking β3 integrins are osteosclerotic because of dysfunctional osteoclasts

2000 • 715 citations

Waardenburg syndrome type 2 caused by mutations in the human microphthalmia (MITF) gene

1994 • 661 citations

microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family.

1994 • 652 citations

Pleiotropic effects of a null mutation in the c-fos proto-oncogene

1992 • 643 citations

MAP kinase links the transcription factor Microphthalmia to c-Kit signalling in melanocytes

1998 • 617 citations

Macrophage colony-stimulating factor is indispensable for both proliferation and differentiation of osteoclast progenitors.

1993 • 565 citations

Osteopetrosis in mice lacking haematopoietic transcription factor PU.1

1997 • 531 citations

c-Kit triggers dual phosphorylations, which couple activation and degradation of the essential melanocyte factor Mi

2000 • 517 citations

Molecular basis of mouse microphthalmia (mi) mutations helps explain their developmental and phenotypic consequences

1994 • 503 citations

TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer muE3 motif.

1990 • 484 citations

MACROPHAGE COLONY STIMULATING FACTOR RESTORESIN VIVOBONE RESORPTION IN THEOP/OPOSTEOPETROTIC MOUSE

1990 • 441 citations

Vascular Endothelial Growth Factor Can Substitute for Macrophage Colony-Stimulating Factor in the Support of Osteoclastic Bone Resorption

1999 • 438 citations

A Combination of Osteoclast Differentiation Factor and Macrophage-Colony Stimulating Factor Is Sufficient for both Human and Mouse Osteoclast Formation in Vitro

1998 • 418 citations

Colony-stimulating factor-1 receptor

1990 • 362 citations

Bone Resorption Restored in Osteopetrotic Mice by Transplants of Normal Bone Marrow and Spleen Cells

1975 • 343 citations

Enforced Expression of Bcl-2 in Monocytes Rescues Macrophages and Partially Reverses Osteopetrosis in op/op Mice

1997 • 292 citations

Essential role of macrophage colony-stimulating factor in the osteoclast differentiation supported by stromal cells.

1991 • 284 citations

Rapid publication: Impairment of macrophage colony-stimulating factor production and lack of resident bone marrow macrophages in the osteopetrotic op/op Mouse

1990 • 272 citations

Regulation of Microphthalmia-Associated Transcription Factor MITF Protein Levels by Association with the Ubiquitin-Conjugating Enzyme hUBC9

2000 • 234 citations

Linking osteopetrosis and pycnodysostosis: Regulation of cathepsin K expression by the microphthalmia transcription factor family

2001 • 215 citations

Lineage-specific Signaling in Melanocytes

1998 • 191 citations

CBP/p300 as a co-factor for the Microphthalmia transcription factor

1997 • 177 citations

Differential Utilization of Trk Autophosphorylation Sites

1996 • 162 citations

Structural organization of the human microphthalmia-associated transcription factor gene containing four alternative promoters

2000 • 141 citations

The Microphthalmia Transcription Factor Regulates Expression of the Tartrate-Resistant Acid Phosphatase Gene During Terminal Differentiation of Osteoclasts

2000 • 131 citations

A Dominant Negative form of Transcription Activator mTFE3 Created by Differential Splicing

1991 • 129 citations

Early Events in M-CSF Receptor Signaling

2000 • 128 citations

Macrophage colony-stimulating factor induces substantial osteoclast generation and bone resorption in human bone marrow cultures

1996 • 112 citations

Genomic, Transcriptional and Mutational Analysis of the Mouse microphthalmia Locus

2000 • 105 citations

KIT ligand (mast cell growth factor) inhibits the growth of KIT-expressing melanoma cells.

1993 • 104 citations

Cloning and Characterization of the Murine Genes for bHLH-ZIP Transcription Factors TFEC and TFEB Reveal a Common Gene Organization for All MiT Subfamily Members

1999 • 95 citations

Fusion disability of embryonic osteoclast precursor cells and macrophages in the microphthalmic osteopetrotic mouse

1985 • 89 citations

Age-resolving Osteopetrosis: A Rat Model Implicating Microphthalmia and the Related Transcription Factor TFE3

1998 • 85 citations

Evidence for a Functional Association between Phosphatidylinositol 3-Kinase and c-src in the Spreading Response of Osteoclasts to Colony-Stimulating Factor-1*

2000 • 82 citations

The c-fms gene complements the mitogenic defect in mast cells derived from mutant W mice but not mi (microphthalmia) mice.

1991 • 69 citations

mTFE3, an X-Linked Transcriptional Activator Containing Basic Helix-Loop-Helix and Zipper Domains, Utilizes the Zipper To Stabilize Both DNA Binding and Multimerization

1992 • 65 citations

Granulocyte/Macrophage Colony-Stimulating Factor and Interleukin-3 Correct Osteopetrosis in Mice with Osteopetrosis Mutation

1999 • 65 citations

Roles of the Mitogen-activated Protein Kinase Family in Macrophage Responses to Colony Stimulating Factor-1 Addition and Withdrawal

1999 • 63 citations

mTFE3, an X-linked transcriptional activator containing basic helix-loop-helix and zipper domains, utilizes the zipper to stabilize both DNA binding and multimerization.

1992 • 26 citations

The osteopetrotic syndrome in the microphthalmic mutant mouse

1973 • 26 citations

Mild osteopetrosis in the microphthalmia-oak ridge mouse. A model for intermediate autosomal recessive osteopetrosis in humans.

1995 • 24 citations

Neonatal reductions in osteoclast number and function account for the transient nature of osteopetrosis in the rat mutation microphthalmia blanc (mib)

1994 • 21 citations

Bone metabolism in the osteopetrotic rat mutation microphthalmia blanc

1995 • 11 citations

Deleted Work

1955 • 0 citations