High selectivity with low specificity: how SecB has solved the paradox of chaperone binding

Facilitated Target Location in Biological Systems

1989 • 1,011 citations

Correlation of competence for export with lack of tertiary structure of the mature species: A study in vivo of maltose-binding protein in E. coli

1986 • 473 citations

The 2.3-A resolution structure of the maltose- or maltodextrin-binding protein, a primary receptor of bacterial active transport and chemotaxis.

1991 • 459 citations

THE ENZYMOLOGY OF PROTEIN TRANSLOCATION ACROSS THE Escherichia coli PLASMA MEMBRANE

1991 • 442 citations

Evidence for specificity at an early step in protein export in Escherichia coli

1985 • 272 citations

The Structural Basis of Sequence-Independent Peptide Binding by OppA Protein

1994 • 226 citations

A Kinetic Partitioning Model of Selective Binding of Nonnative Proteins by the Bacterial Chaperone SecB

1991 • 225 citations

Close encounters: why unstructured, polymeric domains can increase rates of specific macromolecular association

1993 • 177 citations

No Specific Recognition of Leader Peptide by SecB, a Chaperone Involved in Protein Export

1990 • 141 citations

Peptide Binding by Chaperone SecB: Implications for Recognition of Nonnative Structure

1992 • 120 citations

Effects of Escherichia coli secB mutations on pre-maltose binding protein conformation and export kinetics.

1988 • 117 citations

Highly selective binding of nascent polypeptides by an Escherichia coli chaperone protein in vivo

1993 • 107 citations

Role of the leader peptide of maltose-binding protein in two steps of the export process

1988 • 72 citations

Folding of maltose-binding protein. Evidence for the identity of the rate-determining step in vivo and in vitro.

1993 • 71 citations

SecB Protein Stabilizes a Translocation-Competent State of Purified prePhoE Protein

1989 • 67 citations

In‐vitro studies on the folding characteristics of the Escherichia coli precursor protein prePhoE

1992 • 38 citations

Ribose and glucose-galactose receptors

1992 • 30 citations

Involvement of SecB, a chaperone, in the export of ribose-binding protein

1992 • 28 citations

Requirement of the SecB chaperone for export of a non-secretory polypeptide in Escherichia coli

1991 • 27 citations

SecB: A Molecular Chaperone of Escherichia Coli Protein Secretion Pathway

1993 • 27 citations