Requirement of the SecB chaperone for export of a non-secretory polypeptide in Escherichia coli

Experiments in molecular genetics

1972 • 28,260 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

1978 • 4,566 citations

Empirical Predictions of Protein Conformation

1978 • 3,167 citations

Culture Medium for Enterobacteria

1974 • 3,002 citations

Transposition and fusion of the lac genes to selected promoters in Escherichia coli using bacteriophage lambda and Mu

1976 • 1,895 citations

Correlation of competence for export with lack of tertiary structure of the mature species: A study in vivo of maltose-binding protein in E. coli

1986 • 473 citations

Models for the structure of outer-membrane proteins of Escherichia coli derived from raman spectroscopy and prediction methods

1986 • 365 citations

Protein localization in E. coli: Is there a common step in the secretion of periplasmic and outer-membrane proteins?

1981 • 359 citations

The antifolding activity of SecB promotes the export of the E. coli maltose-binding protein

1988 • 326 citations

Rapid Mapping of Conditional and Auxotrophic Mutations in Escherichia coli K-12

1973 • 318 citations

pACYC184-derived cloning vectors containing the multiple cloning site and lacZα reporter gene of pUC8/9 and pUC18/19 plasmids

1988 • 299 citations

pUR 250 allows rapid chemical sequencing of both DNA strands of its inserts

1982 • 273 citations

Evidence for specificity at an early step in protein export in Escherichia coli

1985 • 272 citations

Mutations in a new gene, secB, cause defective protein localization in Escherichia coli

1983 • 270 citations

Effects of mutations in heat-shock genes groES and groEL on protein export in Escherichia coli.

1989 • 250 citations

Modulation of Folding Pathways of Exported Proteins by the Leader Sequence

1988 • 243 citations

High-frequency generalised transduction by bacteriophage T4

1979 • 204 citations

Escherichia coli K-12 outer membrane protein (OmpA) as a bacteriophage receptor: analysis of mutant genes expressing altered proteins

1984 • 192 citations

Construction of an Hfr strain useful for transferring recA mutations between Escherichia coli strains

1980 • 188 citations

Physiological role during export for the retardation of folding by the leader peptide of maltose-binding protein.

1989 • 158 citations

No Specific Recognition of Leader Peptide by SecB, a Chaperone Involved in Protein Export

1990 • 141 citations

Toward a better understanding of protein folding pathways.

1988 • 127 citations

The nature of information, required for export and sorting, present within the outer membrane protein OmpA of Escherichia coli K-12.

1985 • 114 citations

The precursor of beta-lactamase: purification, properties and folding kinetics.

1989 • 110 citations

SecB functions as a cytosolic signal recognition factor for protein export in E. coli

1989 • 107 citations

The mature portion of Escherichia coli maltose-binding protein (MBP) determines the dependence of MBP on SecB for export

1989 • 97 citations

Retardation of folding as a possible means of suppression of a mutation in the leader sequence of an exported protein.

1988 • 95 citations

Cytosolic factor purified from Escherichia coli is necessary and sufficient for the export of a preprotein and is a homotetramer of SecB.

1989 • 83 citations

Cloned structural gene (ompA) for an integral outer membrane protein of Escherichia coli K-12

1980 • 69 citations

Radioimmunological screening method for specific membrane proteins

1979 • 69 citations

Characterization of the Escherichia coli protein-export gene secB

1989 • 69 citations

Suppression of a signal sequence mutation by an amino acid substitution in the mature portion of the maltose-binding protein

1987 • 54 citations

Two structural genes on different chromosomes are required for encoding the major subunit of human red cell glucose-6-phosphate dehydrogenase

1989 • 50 citations

The distal half of the tail fibre of bacteriophage T4

1979 • 43 citations

The signal sequence suffices to direct export of outer membrane protein OmpA of Escherichia coli K-12

1987 • 42 citations

The signal sequence of an Escherichia coli outer membrane protein can mediate translocation of a not normally secreted protein across the plasma membrane.

1987 • 36 citations

The role of the mature part of secretory proteins in translocation across the plasma membrane and in regulation of their synthesis in Escherichia coli

1990 • 35 citations

Morphogenesis of the long tail fibers of bacteriophage T2 involves proteolytic processing of the polypeptide (gene product 37) constituting the distal part of the fiber

1986 • 20 citations