Methylation of SPT5 Regulates Its Interaction with RNA Polymerase II and Transcriptional Elongation Properties

The language of covalent histone modifications

2000 • 8,260 citations

Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails

2001 • 1,480 citations

Regulation of Transcription by a Protein Methyltransferase

1999 • 1,169 citations

A Unified Theory of Gene Expression

2002 • 896 citations

NELF, a Multisubunit Complex Containing RD, Cooperates with DSIF to Repress RNA Polymerase II Elongation

1999 • 797 citations

Methylation of Histone H4 at Arginine 3 Facilitating Transcriptional Activation by Nuclear Hormone Receptor

2001 • 758 citations

DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs

1998 • 718 citations

Histone Methylation

2002 • 525 citations

RNA and Protein Interactions Modulated by Protein Arginine Methylation

1998 • 499 citations

Arginine Methylation of STAT1 Modulates IFNα/β-Induced Transcription

2001 • 475 citations

Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae

1998 • 460 citations

PRMT1 Is the Predominant Type I Protein Arginine Methyltransferase in Mammalian Cells

2000 • 450 citations

Methylation of histone H4 at arginine 3 occurs in vivo and is mediated by the nuclear receptor coactivator PRMT1

2001 • 441 citations

The Mammalian Immediate-early TIS21 Protein and the Leukemia-associated BTG1 Protein Interact with a Protein-arginine -Methyltransferase

1996 • 435 citations

NF-κB Binds P-TEFb to Stimulate Transcriptional Elongation by RNA Polymerase II

2001 • 431 citations

State of the Arg

2001 • 425 citations

A Transcriptional Switch Mediated by Cofactor Methylation

2001 • 407 citations

The Methylosome, a 20S Complex Containing JBP1 and pICln, Produces Dimethylarginine-Modified Sm Proteins

2001 • 392 citations

Protein Identification at the Low Femtomole Level from Silver-Stained Gels Using a New Fritless Electrospray Interface for Liquid Chromatography–Microspray and Nanospray Mass Spectrometry

1998 • 386 citations

Tackling tat

1999 • 375 citations

Symmetrical dimethylation of arginine residues in spliceosomal Sm protein B/B′ and the Sm-like protein LSm4, and their interaction with the SMN protein

2001 • 361 citations

PRMT5 (Janus Kinase-binding Protein 1) Catalyzes the Formation of Symmetric Dimethylarginine Residues in Proteins

2001 • 352 citations

Evidence that P-TEFb alleviates the negative effect of DSIF on RNA polymerase II-dependent transcription invitro

1998 • 343 citations

The Paf1 complex physically and functionally associates with transcription elongation factors in vivo

2002 • 323 citations

The Novel Human Protein Arginine N-Methyltransferase PRMT6 Is a Nuclear Enzyme Displaying Unique Substrate Specificity

2002 • 322 citations

Exchange of RNA Polymerase II Initiation and Elongation Factors during Gene Expression In Vivo

2002 • 311 citations

PRMT 3, a Type I Protein Arginine N-Methyltransferase That Differs from PRMT1 in Its Oligomerization, Subcellular Localization, Substrate Specificity, and Regulation

1998 • 302 citations

The Human Homologue of the Yeast Proteins Skb1 and Hsl7p Interacts with Jak Kinases and Contains Protein Methyltransferase Activity

1999 • 276 citations

High-resolution localization of Drosophila Spt5 and Spt6 at heat shock genes in vivo: roles in promoter proximal pausing and transcription elongation

2000 • 273 citations

Tat Modifies the Activity of CDK9 To Phosphorylate Serine 5 of the RNA Polymerase II Carboxyl-Terminal Domain during Human Immunodeficiency Virus Type 1 Transcription

2000 • 260 citations

Domains in the SPT5 Protein That Modulate Its Transcriptional Regulatory Properties

2000 • 223 citations

Negative regulation of transcription by the type II arginine methyltransferase PRMT5

2002 • 222 citations

Spt5 and Spt6 are associated with active transcription and have characteristics of general elongation factors in D. melanogaster

2000 • 221 citations

Evidence that Negative Elongation Factor Represses Transcription Elongation through Binding to a DRB Sensitivity-Inducing Factor/RNA Polymerase II Complex and RNA

2002 • 217 citations

Transcription elongation factor hSPT5 stimulates mRNA capping

1999 • 210 citations

CDK-9/cyclin T (P-TEFb) is required in two postinitiation pathways for transcription in the C. elegans embryo

2002 • 200 citations

Positive Transcription Elongation Factor b Phosphorylates hSPT5 and RNA Polymerase II Carboxyl-terminal Domain Independently of Cyclin-dependent Kinase-activating Kinase

2001 • 193 citations

A regulator of transcriptional elongation controls vertebrate neuronal development

2000 • 167 citations

Identification of Protein Arginine Methyltransferase 2 as a Coactivator for Estrogen Receptor α

2002 • 159 citations

Structure and Function of the Human Transcription Elongation Factor DSIF

1999 • 140 citations

PRMT5, Which Forms Distinct Homo-oligomers, Is a Member of the Protein-arginine Methyltransferase Family

2001 • 134 citations

Novel domains and orthologues of eukaryotic transcription elongation factors

2002 • 126 citations

Spt5 Cooperates with Human Immunodeficiency Virus Type 1 Tat by Preventing Premature RNA Release at Terminator Sequences

2002 • 112 citations

FACT Relieves DSIF/NELF-Mediated Inhibition of Transcriptional Elongation and Reveals Functional Differences between P-TEFb and TFIIH

2000 • 110 citations

The elongation factors Pandora/Spt6 and Foggy/Spt5 promote transcription in the zebrafish embryo

2002 • 106 citations

Analysis of the Yeast Arginine Methyltransferase Hmt1p/Rmt1p and Its in Vivo Function

2000 • 96 citations

Exposure on Cell Surface and Extensive Arginine Methylation of Ewing Sarcoma (EWS) Protein

2001 • 87 citations

A novel RNA polymerase II-containing complex potentiates Tat-enhanced HIV-1 transcription

1999 • 80 citations

Role of the human homolog of the yeast transcription factor SPT5 in HIV-1 tat-activation

1998 • 67 citations

Tat-SF1 Protein Associates with RAP30 and Human SPT5 Proteins

1999 • 51 citations

Cloning and Mapping of a Novel Human cDNA Homologous to DROER, the Enhancer of theDrosophila melanogasterRudimentary Gene

1996 • 20 citations