Bacterial fitness and plasmid loss: the importance of culture conditions and plasmid size

REPLICA PLATING AND INDIRECT SELECTION OF BACTERIAL MUTANTS

1952 • 1,360 citations

The biological cost of antibiotic resistance

1999 • 868 citations

THE STATIONARY PHASE OF THE BACTERIAL LIFE CYCLE

1993 • 786 citations

Unique type of plasmid maintenance function: postsegregational killing of plasmid-free cells.

1986 • 650 citations

Multimerization of high copy number plasmids causes instability: Cole 1 encodes a determinant essential for plasmid monomerization and stability

1984 • 443 citations

Effects of recombinant plasmid content on growth properties and cloned gene product formation in Escherichia coli

1985 • 242 citations

Replication of plasmids in gram-negative bacteria

1989 • 202 citations

The Influence of the Growth Environment on the Stability of a Drug Resistance Plasmid in Escherichia coli K12

1979 • 189 citations

Segregational instability of pUB110-derived recombinant plasmids in Bacillus subtilis

1985 • 127 citations

COEVOLUTION IN BACTERIAL-PLASMID POPULATIONS

1991 • 105 citations

Effects of segregation and selection on instability of plasmid pACYC184 in Escherichia coli B

1987 • 92 citations

Replication of plasmids in gram-negative bacteria.

1989 • 87 citations

Instability of recombinant pUB110 plasmids in Bacillus subtilis: Plasmid-encoded stability function and effects of DNA inserts

1988 • 87 citations

Effects of genes exerting growth inhibition and plasmid stability on plasmid maintenance

1987 • 80 citations

Plasmid stability in immobilized and free recombinant Escherichia coli JM105(pKK223-200): importance of oxygen diffusion, growth rate, and plasmid copy number

1987 • 74 citations

Phenotypic conversion of drug-resistant bacteria to drug sensitivity

1997 • 72 citations

Plasmid expression and maintenance during long-term starvation-survival of bacteria in well water

1989 • 61 citations

"Easypreps": fast and easy plasmid minipreparation for analysis of recombinant clones in E. coli.

1993 • 48 citations

The insertion of large pieces of foreign genetic material reduces the stability of bacterial plasmids

1986 • 42 citations

Long-term starvation-induced loss of antibiotic resistance in bacteria

1990 • 42 citations

Characterization and complementation of pMB1 copy number mutant: effect of RNA I gene dosage on plasmid copy number and incompatibility

1983 • 38 citations

Parameters affecting plasmid stability in Bacillus subtilis

1991 • 30 citations

E. coliGrowth Inhibition by a High Copy Number Derivative of Plasmid pBR322

1996 • 24 citations

Metabolic enhancement due to plasmid maintenance

1994 • 23 citations

Maintenance of multicopy plasmid Clo DF13

1985 • 7 citations

Technical information sheet no. 12: Plasmid isolation from bacteria: some fast procedures

1995 • 5 citations