Oxidative Stress Induces ADAM9 Protein Expression in Human Prostate Cancer Cells

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

2001 • 156,143 citations

Oxidative Stress, Caloric Restriction, and Aging

1996 • 3,136 citations

Prooxidant States and Tumor Promotion

1985 • 2,541 citations

Production of large amounts of hydrogen peroxide by human tumor cells.

1991 • 2,465 citations

The microenvironment of the tumour–host interface

2001 • 2,307 citations

Molecular mechanisms of N -acetylcysteine actions

2003 • 1,281 citations

Androgen-independent cancer progression and bone metastasis in the LNCaP model of human prostate cancer.

1994 • 731 citations

Modulation of transcription factor NF-kappa B binding activity by oxidation-reduction in vitro.

1991 • 649 citations

Free radicals and antioxidants in food andin vivo:What they do and how they work

1995 • 643 citations

Intracellular hydrogen peroxide and superoxide anion detection in endothelial cells

1994 • 637 citations

A metalloprotease-disintegrin, MDC9/meltrin-gamma /ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor

1998 • 523 citations

Hydrogen peroxide mediates the cell growth and transformation caused by the mitogenic oxidase Nox1

2001 • 478 citations

Acceleration of human prostate cancer growth in vivo by factors produced by prostate and bone fibroblasts.

1991 • 449 citations

THE ROLE OF INFLAMMATION IN THE PATHOGENESIS OF PROSTATE CANCER

2004 • 392 citations

LNCaP progression model of human prostate cancer: Androgen-independence and osseous metastasis

2000 • 356 citations

Mitochondrial DNA repair and aging

2002 • 340 citations

Increased Nox1 and hydrogen peroxide in prostate cancer

2004 • 317 citations

Free radicals in aging

1988 • 314 citations

Metalloprotease-Disintegrin MDC9: Intracellular Maturation and Catalytic Activity

1999 • 312 citations

Diverse and Specific Gene Expression Responses to Stresses in Cultured Human Cells

2004 • 295 citations

C-met Proto-Oncogene Expression in Benign and Malignant Human Prostate Tissues

1995 • 267 citations

Activator protein 1 (AP-1)– and nuclear factor κB (NF-κB)–dependent transcriptional events in carcinogenesis

2000 • 265 citations

NOX5 NAD(P)H oxidase regulates growth and apoptosis in DU 145 prostate cancer cells

2003 • 254 citations

Androgen-repressed phenotype in human prostate cancer

1996 • 229 citations

Mitochondrial genome instability in human cancers

2001 • 194 citations

Meltrin γ (ADAM-9) mediates cellular adhesion through α6β1 integrin, leading to a marked induction of fibroblast cell motility

2000 • 190 citations

A Secreted Form of ADAM9 Promotes Carcinoma Invasion through Tumor-Stromal Interactions

2005 • 184 citations

Interaction of the Metalloprotease Disintegrins MDC9 and MDC15 with Two SH3 Domain-containing Proteins, Endophilin I and SH3PX1

1999 • 182 citations

Prediction of sensitivity of advanced non-small cell lung cancers to gefitinib (Iressa, ZD1839)

2004 • 174 citations

Alterations in gene expression profiles during prostate cancer progression: functional correlations to tumorigenicity and down-regulation of selenoprotein-P in mouse and human tumors.

2002 • 174 citations

The disintegrin-metalloproteinases ADAM9, ADAM12, and ADAM15 are upregulated in gastric cancer

2005 • 155 citations

Flow cytometric detection of hydrogen peroxide production induced by doxorubicin in cancer cells

1994 • 151 citations

Oxidative and Osmotic Stress Signaling in Tumor Cells Is Mediated by ADAM Proteases and Heparin-Binding Epidermal Growth Factor

2004 • 149 citations

Expression of ADAM‐9 mRNA and protein in human breast cancer

2003 • 138 citations

Overexpression of ADAM9 in Non-Small Cell Lung Cancer Correlates with Brain Metastasis

2004 • 135 citations

ADAM9 expression in pancreatic cancer is associated with tumour type and is a prognostic factor in ductal adenocarcinoma

2004 • 133 citations

Oxidative stress and cyclooxygenase activity in prostate carcinogenesis: targets for chemopreventive strategies

2004 • 131 citations

Critical Function for ADAM9 in Mouse Prostate Cancer

2005 • 113 citations

Expression of ADAMs (a disintegrin and metalloproteases) and TIMP-3 (tissue inhibitor of metalloproteinase-3) in human prostatic adenocarcinomas

2003 • 95 citations

Evidence for an interaction of the metalloprotease-disintegrin tumour necrosis factor alpha convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease-disintegrin MDC9 with a novel MAD2-related protein, MAD2beta.

1999 • 84 citations

MDC-9 (ADAM-9/Meltrin γ) Functions as an Adhesion Molecule by Binding the αvβ5 Integrin

2001 • 84 citations

The expression of the ADAMs proteases in prostate cancer cell lines and their regulation by dihydrotestosterone

2000 • 82 citations

Lysyl oxidase oxidizes basic fibroblast growth factor and inactivates its mitogenic potential

2002 • 67 citations

Oncogenic conversion of Ets affects redox regulationin-vivoandin-vitro

1993 • 54 citations

Cloning and Expression in Pichia pastoris of Metalloprotease Domain of ADAM 9 Catalytically Active against Fibronectin

2001 • 54 citations

Evidence for an interaction of the metalloprotease–disintegrin tumour necrosis factor α convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease–disintegrin MDC9 with a novel MAD2-related protein, MAD2β

1999 • 53 citations

Reactive Nitrogen Species in Colon Carcinogenesis

1999 • 52 citations

Activation of oncogenes and/or inactivation of anti-oncogenes by reactive oxygen species

1992 • 52 citations

H2O2 oxidative damage in cultured oral epithelial cells: the effect of short-term vitamin C exposure.

2001 • 19 citations

Developmental expression of metalloproteases ADAM 9, 10, and 17 becomes restricted to divergent pancreatic compartments

2005 • 13 citations

Cancer prevention: optimizing life-styles with special reference to nutritional carcinogenesis.

1992 • 7 citations

396: Radiation Induction of Adam9 Expression Promoted Prostate Cancer Cell Survival: Possible Mechanism and Potential Therapeutic Application

2005 • 1 citations

Deleted Work

1955 • 0 citations