Nucleotide Sequence of Human Preproinsulin Complementary DNA

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A new method for sequencing DNA.

1977 • 7,941 citations

Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene.

1975 • 3,483 citations

Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma.

1975 • 3,026 citations

Rat Insulin Genes: Construction of Plasmids Containing the Coding Sequences

1977 • 1,252 citations

A Possible Precursor of Immunoglobulin Light Chains

1972 • 609 citations

THE BIOSYNTHESIS OF INSULIN AND A PROBABLE PRECURSOR OF INSULIN BY A HUMAN ISLET CELL ADENOMA

1967 • 608 citations

Direct expression in Escherichia coli of a DNA sequence coding for human growth hormone

1979 • 517 citations

A bacterial clone synthesizing proinsulin.

1978 • 515 citations

The structure and evolution of the two nonallelic rat preproinsulin genes

1979 • 500 citations

Conservation of the primary structure at the 3′ end of 18S rRNA from eucaryotic cells

1978 • 427 citations

Synthesis of double-stranded DNA complementary to lysozyme, ovomucoid, and ovalbumin mRNAs. Optimization for full length second strand synthesis by Escherichia coli DNA polymerase I.

1978 • 395 citations

Porcine Proinsulin: Characterization and Amino Acid Sequence

1968 • 318 citations

Cell-free synthesis of rat preproinsulins: characterization and partial amino acid sequence determination.

1976 • 279 citations

Mapping of the residues responsible for the negative cooperativity of the receptor-binding region of insulin

1978 • 223 citations

Cell-free synthesis of fish preproinsulin, and processing by heterologous mammalian microsomal membranes.

1977 • 182 citations

Nucleotide sequence of a cDNA clone encoding human preproinsulin

1979 • 141 citations

Studies on Human Proinsulin

1971 • 129 citations

Preparation of pancreatic mRNA: cell-free translation of an insulin-immunoreactive polypeptide.

1976 • 101 citations

Immunological and chemical characterization of bovine preproinsulin.

1977 • 60 citations

The Amino Acid Sequence of the C‐Peptide of Human Proinsulin

1971 • 43 citations

Sequence of the 5′-end of Strongylocentrotus purpuratus H2b histone mRNA and its location within histone DNA

1979 • 34 citations

Translation of messenger ribonucleic acid from isolated pancreatic islets and human insulinomas.

1975 • 28 citations

Proinsulin precursors in isolated rat pancreatic islets

1977 • 13 citations