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Mapping of the residues responsible for the negative cooperativity of the receptor-binding region of insulin

Data up to Jan 2025

Published1978
Citations223
References30

Total Citations Per Year

Abstract

References (30)

Insulin: The Structure in the Crystal and its Reflection in Chemistry and Biology by

1972 • 831 citations

Insulin interactions with its receptors: Experimental evidence for negative cooperativity

1973 • 717 citations

Site-site interactions among insulin receptors. Characterization of the negative cooperativity.

1976 • 601 citations

Insulin Receptors in the Liver: Specific Binding of [ 125 I]Insulin to the Plasma Membrane and Its Relation to Insulin Bioactivity

1971 • 494 citations

Receptor-binding region of insulin

1976 • 389 citations

Species variation in the amino acid sequence of insulin

1966 • 322 citations

Characteristics of the Human Lymphocyte Insulin Receptor

1973 • 320 citations

Porcine Proinsulin: Characterization and Amino Acid Sequence

1968 • 318 citations

Methods in receptor research

1976 • 317 citations

Binding of insuling and other hormones to non-receptor materials: Saturability, specificity and apparent “negative cooperativity”

1975 • 197 citations

Zinc binding, circular dichroism, and equilibrium sedimentation studies on insulin (bovine) and several of its derivatives

1974 • 197 citations

Cooperative properties of hormone receptors in cell membranes

1976 • 170 citations

Amino-terminal sequences of two polypeptides from human serum with nonsuppressible insulin-like and cell-growth-promoting activities: evidence for structural homology with insulin B chain.

1976 • 161 citations

Is the evolution of insulin Darwinian or due to selectively neutral mutation?

1975 • 151 citations

The biological activity and the binding affinity of modified insulins determined on isolated rat fat cells

1974 • 133 citations

The Relation of Conformation and Association of Insulin to Receptor Binding; X‐Ray and Circular‐Dichroism Studies on Bovine and Hystricomorph Insulins

1975 • 117 citations

The acetylation of insulin

1971 • 102 citations

Relationship of structure to biological activity of insulin as revealed by degradative studies

1966 • 97 citations

Molecular basis of negative co-operativity in rabbit muscle glyceraldehyde-3-phosphate dehydrogenase

1974 • 95 citations

Receptor-binding assay of chemically modified insulins

1974 • 81 citations

Guinea Pig Insulin

1974 • 47 citations

Structural and crystallographic observations on hagfish insulin

1974 • 42 citations

Des-PheB1-Insulin, ein kristallines Analogon des Rinderinsulins

1969 • 40 citations

Preparation and characterization of diphenylthiocarbamyl-insulin and des-GlyA1-des-PheB1-insulin (bovine)

1970 • 38 citations

Synthesis and properties of carbonylbis(methionyl)insulin, a proinsulin analog which is convertible to insulin by cyanogen bromide cleavage

1976 • 36 citations

Darstellung und Eigenschaften von Acetylderivaten des Rinderinsulins, I

1972 • 36 citations

Radioreceptor Assay of Insulin: Comparison of Plasma and Pancreatic Insulins and Proinsulins

1975 • 35 citations

Physical and biological properties of guinea pig insulin

1972 • 31 citations

Studies on Insulin

1962 • 30 citations

Low resolution crystal structure of hagfish insulin

1974 • 30 citations

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Mapping of the residues responsible for the negative cooperativity of the… (1978) – Nature | Metascience Observatory Explorer