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Protein kinase C isoenzymes: divergence in signal transduction?

Data up to Jan 2025

Published1993
Citations1,237
References218

Total Citations Per Year

Abstract

References (218)

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1988 • 4,243 citations

Inositol phosphates and cell signalling

1989 • 4,058 citations

INOSITOL TRISPHOSPHATE AND DIACYLGLYCEROL: TWO INTERACTING SECOND MESSENGERS

1987 • 3,302 citations

A novel arachidonic acid-selective cytosolic PLA2 contains a Ca2+-dependent translocation domain with homology to PKC and GAP

1991 • 1,709 citations

Activation in vitro of NF-κB" by phosphorylation of its inhibitor IκB"

1990 • 1,202 citations

Calcium-dependent activation of a multifunctional protein kinase by membrane phospholipids.

1979 • 1,139 citations

cAMP-DEPENDENT PROTEIN KINASE: FRAMEWORK FOR A DIVERSE FAMILY OF REGULATORY ENZYMES

1990 • 1,121 citations

Multiple, Distinct Forms of Bovine and Human Protein Kinase C Suggest Diversity in Cellular Signaling Pathways

1986 • 1,044 citations

TRANSLATIONAL CONTROL IN MAMMALIAN CELLS

1991 • 1,041 citations

Protein Kinase C Contains a Pseudosubstrate Prototope in Its Regulatory Domain

1987 • 1,020 citations

Protein kinase recognition sequence motifs

1990 • 1,014 citations

Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

1990 • 949 citations

Protein kinase C

1991 • 914 citations

A Retroviral Oncogene, akt , Encoding a Serine-Threonine Kinase Containing an SH2-Like Region

1991 • 900 citations

Stimulation of p21ras upon T-cell activation

1990 • 882 citations

The Complete Primary Structure of Protein Kinase C—the Major Phorbol Ester Receptor

1986 • 878 citations

Regulation of brain Type II Ca2+/calmodulin-dependent protein kinase by autophosphorylation: A Ca2+-triggered molecular switch

1986 • 856 citations

Sgk1-Dependent Stimulation of Cardiac Na+/H+Exchanger Nhe1 by Dexamethasone

2013 • 842 citations

Phospholipid binding by a synaptic vesicle protein homologous to the regulatory region of protein kinase C

1990 • 829 citations

Cooperation between oncogenes

1991 • 792 citations

THE PROTEIN KINASE C FAMILY: HETEROGENEITY AND ITS IMPLICATIONS

1989 • 739 citations

MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium–calmodulin

1992 • 728 citations

The structure, expression, and properties of additional members of the protein kinase C family.

1988 • 706 citations

Cloning and expression of multiple protein kinase C cDNAs

1986 • 683 citations

Proteolytic activation of calcium-activated, phospholipid-dependent protein kinase by calcium-dependent neutral protease.

1983 • 601 citations

Lipid activation of protein kinase C.

1991 • 566 citations

The Role of Protein Kinase C in Transmembrane Signalling

1986 • 557 citations

Sequence similarity of phospholipase C with the non-catalytic region of src

1988 • 541 citations

Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily.

1991 • 537 citations

K562 human leukaemic cells synthesise embryonic haemoglobin in response to haemin

1979 • 532 citations

Direct activation of the serine/threonine kinase activity of raf-1 through tyrosine phosphorylation by the PDGF β-receptor

1989 • 513 citations

Protein kinase C zeta subspecies from rat brain: its structure, expression, and properties.

1989 • 508 citations

Identification of intracellular receptor proteins for activated protein kinase C.

1991 • 505 citations

Overproduction of protein kinase C causesdisordered growth control in rat fibroblasts

1988 • 492 citations

Raf-1 protein kinase is required for growth of induced NIH/3T3 cells

1991 • 489 citations

Activation of protein kinase C by Triton X-100 mixed micelles containing diacylglycerol and phosphatidylserine.

1985 • 471 citations

Limited Proteolysis of Protein Kinase C Subspecies by Calcium-dependent Neutral Protease (Calpain)

1989 • 470 citations

Tissue-specific expression of three distinct types of rabbit protein kinase C

1987 • 469 citations

The polyphosphoinositide cycle exists in the nuclei of Swiss 3T3 cells under the control of a receptor (for IGF-I) in the plasma membrane, and stimulation of the cycle increases nuclear diacylglycerol and apparently induces translocation of protein kinase

1991 • 454 citations

Serum-, TPA-, and Ras-induced expression from Ap-1/Ets-driven promoters requires Raf-1 kinase.

1992 • 453 citations

Tissue and cellular distribution of the extended family of protein kinase C isoenzymes

1992 • 441 citations

Phorbol ester binding to protein kinase C requires a cysteine-rich zinc-finger-like sequence.

1989 • 439 citations

A phorbol ester receptor/protein kinase, nPKC eta, a new member of the protein kinase C family predominantly expressed in lung and skin.

1990 • 434 citations

A novel phorbol ester receptor/protein kinase, nPKC, distantly related to the protein kinase C family

1988 • 414 citations

The protein kinase C family

1992 • 399 citations

Isozymic forms of rat brain Ca2+-activated and phospholipid-dependent protein kinase.

1986 • 389 citations

In Vitro Activation and Nuclear Translocation of NF-κB Catalyzed by Cyclic AMP-Dependent Protein Kinase and Protein Kinase C

1989 • 389 citations

A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

1991 • 344 citations

A new member of the protein kinase C family, nPKC theta, predominantly expressed in skeletal muscle.

1992 • 340 citations

Protein kinases. Regulation by autoinhibitory domains.

1990 • 322 citations

Expression and Properties of Two Types of Protein Kinase C: Alternative Splicing from a Single Gene

1987 • 317 citations

Autophosphorylation of the protein kinase dependent on double-stranded RNA.

1987 • 301 citations

A synthetic peptide substrate for selective assay of protein kinase C

1990 • 292 citations

Activation of the c-Raf protein kinase by protein kinase C phosphorylation.

1992 • 288 citations

The influence of basic residues on the substrate specificity of protein kinase C.

1987 • 287 citations

Altered growth regulation and enhanced tumorigenicity of NIH 3T3 fibroblasts transfected with protein kinase C-I cDNA

1988 • 285 citations

Purification and characterization of the zeta isoform of protein kinase C from bovine kidney.

1992 • 283 citations

The role of protein kinase C isoenzymes in the regulation of cell proliferation and differentiation

1992 • 265 citations

Potent and Specific Inhibitors of Protein Kinase C of Microbial Origin

1990 • 262 citations

Selective translocation of beta II-protein kinase C to the nucleus of human promyelocytic (HL60) leukemia cells.

1991 • 251 citations

Signal transduction from cell surface to nucleus in development and disease

1992 • 246 citations

Immunochemical evidence that three protein kinase C isozymes increase in abundance during HL-60 differentiation induced by dimethyl sulfoxide and retinoic acid.

1988 • 239 citations

Protein kinase C contains two phorbol ester binding domains.

1991 • 234 citations

Expression, purification, and characterization of protein kinase C-epsilon.

1990 • 231 citations

Synaptotagmin II. A novel differentially distributed form of synaptotagmin

1991 • 231 citations

Unique substrate specificity and regulatory properties of PKC‐ε: a rationale for diversity

1989 • 226 citations

Mode of Activation and Kinetic Properties of Three Distinct Forms of Protein Kinase C from Rat Brain1

1988 • 225 citations

Type 3 protein kinase C localization to the nuclear envelope of phorbol ester-treated NIH 3T3 cells.

1989 • 221 citations

Differential Down-regulation of Protein Kinase C Isozymes

1989 • 219 citations

Isolation and characterization of delta-subspecies of protein kinase C from rat brain.

1992 • 218 citations

Porcine diacylglycerol kinase sequence has zinc finger and E–F hand motifs

1990 • 218 citations

Tissue distribution and developmental expression of protein kinase C isozymes.

1988 • 215 citations

Two types of complementary DNAs of rat brain protein kinase C

1986 • 212 citations

Isolation and characterization of PKC-L, a new member of the protein kinase C-related gene family specifically expressed in lung, skin, and heart.

1991 • 212 citations

GAL4 transcription factor is not a "zinc finger" but forms a Zn(II)2Cys6 binuclear cluster.

1990 • 211 citations

Differential stimulation of phosphorylation of initiation factors eIF-4F, eIF-4B, eIF-3, and ribosomal protein S6 by insulin and phorbol esters.

1990 • 197 citations

The PtdIns-PLC superfamily and signal transduction

1991 • 190 citations

Selective activation of the γ‐subspecies of protein kinase C from bovine cerebellum by arachidonic acid and its lipoxygenase metabolites

1989 • 188 citations

Protein kinase C and T cell activation

1990 • 183 citations

Autophosphorylation of rat brain Ca2+-activated and phospholipid-dependent protein kinase.

1986 • 183 citations

Overexpression of Protein Kinase C in HT29 Colon Cancer Cells Causes Growth Inhibition and Tumor Suppression

1990 • 179 citations

Activation of the PKC‐isotypes α, β1, γ, δ, and ε by phorbol esters of different biological activities

1991 • 178 citations

Purification and characterisation of bovine brain protein kinase C isotypes α, β and γ

1989 • 169 citations

Purification and characterization of three types of protein kinase C from rabbit brain cytosol.

1987 • 168 citations

Domain structure and phosphorylation of protein kinase C.

1987 • 168 citations

Role of substrate in imparting calcium and phospholipid requirements to protein kinase C activation

1987 • 168 citations

Phosphorylation of lamin B at the nuclear membrane by activated protein kinase C.

1988 • 166 citations

Biosynthesis and Posttranslational Modifications of Protein Kinase C in Human Breast Cancer Cells

1989 • 160 citations

Expression of four protein kinase C isoforms in rat fibroblasts. Distinct subcellular distribution and regulation by calcium and phorbol esters.

1992 • 160 citations

Isolation of cDNA clones encoding protein kinase C: evidence for a protein kinase C-related gene family.

1987 • 156 citations

Raf-1: A kinase currently without a cause but not lacking in effects

1991 • 155 citations

Expression of Antisense RNA against Initiation Factor eIF-4E mRNA in HeLa Cells Results in Lengthened Cell Division Times, Diminished Translation Rates, and Reduced Levels of Both eIF-4E and the p220 Component of eIF-4F

1991 • 151 citations

Autophosphorylation of Protein Kinase C at Three Separated Regions of Its Primary Sequence

1990 • 151 citations

T cell antigen receptor engagement stimulates c-raf phosphorylation and induces c-raf-associated kinase activity via a protein kinase C-dependent pathway.

1990 • 147 citations

A point mutation at the putative ATP-binding site of protein kinase C alpha abolishes the kinase activity and renders it down-regulation-insensitive. A molecular link between autophosphorylation and down-regulation.

1990 • 145 citations

Mutagenesis of the pseudosubstrate site of protein kinase C leads to activation

1990 • 144 citations

Expression of protein kinase C genes in hemopoietic cells is cell-type- and B cell-differentiation stage specific.

1991 • 142 citations

Characterization of the phosphorylation sites in the chicken and bovine myristoylated alanine-rich C kinase substrate protein, a prominent cellular substrate for protein kinase C

1989 • 136 citations

Human brain n-chimaerin cDNA encodes a novel phorbol ester receptor

1990 • 136 citations

Nuclear protein phosphorylation and growth control

1992 • 135 citations

Structural and functional diversities of a family of signal transducing protein kinases, protein kinase C family; two distinct classes of PKC, conventional cPKC and novel nPKC

1991 • 134 citations

The regulatory domain of protein kinase C coordinates four atoms of zinc.

1992 • 129 citations

Sustained activation of protein kinase C is essential to HL-60 cell differentiation to macrophage.

1991 • 129 citations

Chemically induced murine erythroleukemic differentiation

1980 • 128 citations

Protein kinase C heterogeneity in GH4C1 rat pituitary cells. Characterization of a Ca2(+)-independent phorbol ester receptor.

1990 • 126 citations

A dictionary of transcription control sequences

1990 • 124 citations

Protein kinase C activation by phorbol esters: do cysteine-rich regions and pseudosubstrate motifs play a role?

1991 • 124 citations

Molecular cloning of mouse protein kinase C (PKC) cDNA from Swiss 3T3 fibroblasts

1988 • 122 citations

EGF induces biphasic S6 kinase activation: Late phase is protein kinase C-dependent and contributes to mitogenicity

1989 • 122 citations

Protein kinase C group B members PKC-δ, -ɛ, -ζ and PKC-L(η). Comparison of properties of recombinant proteins in vitro and in vivo

1992 • 121 citations

Expression of the alpha, beta II, and gamma protein kinase C isozymes in the baculovirus-insect cell expression system. Purification and characterization of the individual isoforms.

1990 • 120 citations

A mutant protein kinase C that can transform fibroblasts

1989 • 119 citations

Possible involvement of RAS-encoded proteins in glucose-induced inositolphospholipid turnover in Saccharomyces cerevisiae.

1986 • 118 citations

Interferon-alpha selectively activates the beta isoform of protein kinase C through phosphatidylcholine hydrolysis.

1990 • 117 citations

High Cooperativity, Specificity, and Multiplicity in the Protein Kinase C-Lipid Interaction

1989 • 116 citations

Phorbol diesters stimulate the accumulation of phosphatidate, phosphatidylethanol, and diacylglycerol in three cell types. Evidence for the indirect formation of phosphatidylcholine-derived diacylglycerol by a phospholipase D pathway and direct formation of diacylglycerol by a phospholipase C pathway.

1990 • 113 citations

Rat liver nuclei protein kinase C is the isozyme type II.

1990 • 112 citations

Protein kinase C isozymes have distinct roles in neural induction and competence in Xenopus

1992 • 110 citations

Distinct mechanisms of regulation of protein kinase C epsilon by hormones and phorbol diesters.

1991 • 107 citations

Structure and properties of a ubiquitously expressed protein kinase C, nPKCδ

1991 • 105 citations

Deletion of the regulatory domain of protein kinase C alpha exposes regions in the hinge and catalytic domains that mediate nuclear targeting.

1992 • 104 citations

Studies on the phosphorylation of protein kinase C-α

1992 • 103 citations

Interaction of protein kinase C with phosphatidylserine. 2. Specificity and regulation

1992 • 102 citations

A protein kinase C cDNA without the regulatory domain is active after transfection in vivo in the absence of phorbol ester.

1989 • 102 citations

Protein kinase C activity and hexamethylenebisacetamide-induced erythroleukemia cell differentiation.

1987 • 101 citations

Lamin B is rapidly phosphorylated in lymphocytes after activation of protein kinase C.

1988 • 101 citations

Activation of resting human T cells requires prolonged stimulation of protein kinase C.

1990 • 99 citations

Primary structures of human protein kinase C βI and βII differ only in their C‐terminal sequences

1987 • 97 citations

Purified I kappa B-beta is inactivated upon dephosphorylation.

1992 • 97 citations

The mechanism of activation of protein kinase C: a biophysical perspective

1992 • 94 citations

Complete Activation of Protein Kinase C by an Antipeptide Antibody Directed against the Pseudosubstrate Prototope

1989 • 94 citations

Expression and characterization of protein kinase C‐δ

1991 • 94 citations

Transmembrane signaling by interferon alpha involves diacylglycerol production and activation of the epsilon isoform of protein kinase C in Daudi cells.

1991 • 89 citations

Overexpression of protein kinase C beta 1 enhances phospholipase D activity and diacylglycerol formation in phorbol ester-stimulated rat fibroblasts.

1991 • 87 citations

Purification and characterization of a calcium-unresponsive, phorbol ester/phospholipid-activated protein kinase from porcine spleen.

1990 • 85 citations

Nucleotide sequences of cDNAs for α and γ subspecies of rat brain protein kinase C

1988 • 85 citations

Mouse protein kinase C-.delta., the major isoform expressed in mouse hemopoietic cells: sequence of the cDNA, expression patterns, and characterization of the protein

1991 • 85 citations

Mechanism of protein kinase C activation by phosphatidylinositol 4,5-bisphosphate

1991 • 84 citations

Protein kinase C autophosphorylates by an intrapeptide reaction.

1987 • 83 citations

Alternative Splicing Increases the Diversity of the Human Protein Kinase C Family

1987 • 83 citations

Phosphorylation of eIF-4F by protein kinase C or multipotential S6 kinase stimulates protein synthesis at initiation.

1991 • 83 citations

Constitutive activity of membrane-inserted protein kinase C

1988 • 83 citations

A fourth type of rabbit protein kinase C

1988 • 80 citations

Purification and characterization of protein kinase C .epsilon. from rabbit brain

1992 • 77 citations

Differential expression of protein kinase C isozymes and erythroleukemia cell differentiation

1989 • 77 citations

Identification and functional characterization of protein kinase C isozymes in platelets and HEL cells.

1992 • 76 citations

Different translocation of three distinct PKC isoforms with tumor-promoting phorbol ester in human platelets

1991 • 76 citations

Overexpression of protein kinase C alpha-subtype in Swiss/3T3 fibroblasts causes loss of both high and low affinity receptor numbers for epidermal growth factor.

1990 • 76 citations

Conversion of protein kinase C from a Ca2+-dependent to an independent form of phorbol ester-binding protein by digestion with trypsim

1986 • 74 citations

The protein kinase C-related PKC-L(eta) gene product is localized in the cell nucleus.

1992 • 74 citations

Expression and partial characterization of rat protein kinase C‐δ and protein kinase C‐ξ in insect cells using recombinant baculovirus

1992 • 73 citations

Temporal changes in intracellular distribution of protein kinase C during differentiation of human leukemia HL60 cells induced by phorbol ester

1988 • 69 citations

Failure of wild-type or a mutant form of protein kinase C-α to transform fibroblasts

1991 • 68 citations

The phosphorylation of protein kinase C as a potential measure of activation

1989 • 68 citations

Immunocharacterization of δ‐ and ζ‐isoenzymes of protein kinase C in rat renal mesangial cells

1992 • 67 citations

Protein kinase C during differentiation of human promyelocytic leukemia cell line, HL‐60

1990 • 67 citations

Protein kinase C pseudosubstrate prototope: Structure-function relationships

1990 • 66 citations

Proteolytic activation of protein kinase C‐ɛ

1990 • 65 citations

Disturbances in growth control and gene expression in a C3H/10T1/2 cell line that stably overproduces protein kinase C.

1989 • 64 citations

Sequence of human protein kinase C α

1990 • 64 citations

Possible role of Ca2+-independent protein kinase C isozyme, nPKCɛ, in thyrotropin- releasing hormone-stimulated signal transduction: Differential down-regulation of nPKCɛ in GH4C1 cells

1990 • 63 citations

Cell type-specific expression of the genes for the protein kinase C family: Down regulation of mRNAs for PKCα and nPKCε upon in vitro differentiation of a mouse neuroblastoma cell line Neuro 2a

1989 • 62 citations

The leucine zipper of c-Myc is required for full inhibition of erythroleukemia differentiation.

1990 • 61 citations

Characterization and differential expression of protein kinase C isoforms in PC12 cells Differentiation parallels an increase in PKC beta11

1992 • 60 citations

Cloning and characterization of the major promoter of the human protein kinase C beta gene. Regulation by phorbol esters.

1992 • 58 citations

A New Member of the Protein Kinase C Family, nPKCθ, Predominantly Expressed in Skeletal Muscle

1992 • 57 citations

A synthetic peptide of the pseudosubstrate domain of protein kinase C blocks cytoplasmic alkalinization during activation of the sea urchin egg

1990 • 56 citations

N-myc disrupts protein kinase C-mediated signal transduction in neuroblastoma.

1991 • 56 citations

The regulatory domain of protein kinase C-ε restricts the catalytic-domain-specificity

1991 • 53 citations

Protein kinase C

1992 • 53 citations

Identification of the proteolytically activated form of protein kinase C in stimulated human neutrophils.

1990 • 53 citations

Intracellular delivery of protein kinase C‐α or ε isoform‐specific antibodies promotes acquisition of a morphologically differentiated phenotype in neuroblastoma cells

1992 • 50 citations

Expression of a functional protein kinase C-γ using a baculovirus vector: Purification and characterisation of a single protein kinase C iso-enzyme

1989 • 47 citations

Heterogeneity of protein kinase C expression and regulation in T lymphocytes

1990 • 46 citations

Isolation and Characterization of PKC-L, A New Member of the Protein Kinase C-Related Gene Family Specifically Expressed in Lung, Skin, and Heart

1991 • 44 citations

Transient shift of diacylglycerol and inositol lipids induced by interferon in Daudi cells

1990 • 43 citations

[55] Expression of protein kinase c isotypes using baculovirus vectors

1991 • 43 citations

Protein kinase C activation and protooncogene expression in differentiation/retrodifferentiation of human U-937 leukemia cells.

1991 • 42 citations

Biochemical properties of rat protein kinase C‐η expressed in COS cells

1992 • 41 citations

Interleukin 3 stimulates phosphatidylcholine turnover in a mast/megakaryocyte cell line

1989 • 40 citations

Activation of purified human protein kinase C α and β I isoenzymes in vitro by Ca2+, phosphatidylinositol and phosphatidylinositol 4,5-bisphosphate

1993 • 39 citations

Downregulation of protein kinase C‐γ is independent of a functional kinase domain

1991 • 37 citations

Down‐regulation of a kinase defective PKC‐α

1991 • 33 citations

Dual role for protein kinase C α as a regulator of ion secretion in the HT29cl.19A human colonic cell line

1992 • 33 citations

Inducible overexpression of human protein kinase C α in NIH 3T3 fibroblasts results in growth abnormalities

1992 • 31 citations

A pseudosubstrate peptide inhibits protein kinase C‐mediated phosphorylation in permeabilized Rat‐1 cells

1990 • 27 citations

Characterization of the 5'-flanking region of the rat protein kinase C gamma gene.

1990 • 26 citations

Down-regulation of protein kinase C in Swiss 3T3 fibroblasts is independent of its phosphorylating activity

1991 • 25 citations

Differential recovery of protein kinase C-α and -ɛ isozymes after long-term phorbol ester treatment in rat renal mesangial cells

1991 • 25 citations

The Leucine Zipper of c-Myc Is Required for Full Inhibition of Erythroleukemia Differentiation

1990 • 23 citations

Positive and negative regulation of the transcription of the human protein kinase C beta gene.

1992 • 23 citations

NPC 15437 interacts with the C1 domain of protein kinase C An analysis using mutant PKC constructs

1991 • 23 citations

Proteinkinase C β-isoform triggers the formation of prostanoids and superoxide in liver macrophages

1992 • 23 citations

c-myb effects on kinetic events during MEL cell differentiation.

1992 • 23 citations

Nucleotide sequence of the 3' portion of a human gene for protein kinase CβI/βII

1987 • 22 citations

A rise and fall in 1,2-diacylglycerol content signal hexamethylene bisacetamide-induced erythropoiesis.

1992 • 22 citations

Isolation of cloned mouse protein kinase C beta-II cDNA and its sequence

1990 • 22 citations

The hormonal control of gene transcription

1992 • 21 citations

Phenotypic effects of overexpression of PKCβ1 in rat liver epithelial cells

1989 • 21 citations

Retinoic Acid-Specific Induction of a Protein Kinase C Isoform during Differentiation of HL-60 Cells1

1992 • 20 citations

Activation of two discrete signaling pathways by erythropoietin.

1992 • 19 citations

Protein kinase C isozymes epsilon and alpha in murine erythroleukemia cells.

1992 • 19 citations

Identification of the phosphoserine residue in histone H1 phosphorylated by protein kinase C

1988 • 19 citations

Tumor promoter 12-O-tetradecanoylphorbol-13-acetate and sn-1,2-dioctanoylglycerol increase the phosphorylation of protein kinase C in cells.

1991 • 19 citations

Specificity of protein phosphatases in the dephosphorylation of protein kinase C

1986 • 17 citations

Expression of protein kinase C I in NIH 3T3 cells increases its growth response to specific activators

1990 • 16 citations

Modulation of the mitogenic activity of eukaryotic translation initiation factor-4E by protein kinase C.

1991 • 15 citations

Effects of protein kinase A and calcium/phospholipid-dependent kinase modulators in the process of HL-60 cell differentiation: their opposite effects between HL-60 cell and K-562 cell differentiation.

1991 • 12 citations

High‐efficiency expression of rat protein kinase C‐γ in baculovirus‐infected insect cells

1990 • 12 citations

Activation of protein kinase C by phosphatidylinositol 4,5-bisphosphate: Possible involvement in Na+H+ antiport down-regulation and cell proliferation

1991 • 11 citations

Identification of phosphatidylserine-binding proteins in human white blood cells

1990 • 10 citations

Protein kinase C gamma expression mimics phorbol ester-induced transcriptional activation of a murine VL30 enhancer element.

1991 • 9 citations

A (re)initiation‐dependent cell‐free protein‐synthesis system from mouse erythroleukemia cells

1986 • 9 citations

The Protein Kinase C-Related PKC-L(η) Gene Product Is Localized in the Cell Nucleus

1992 • 8 citations

Interleukin-3 induces translocation and down-regulation of protein kinase C in human platelets

1992 • 8 citations

Stimulation of proliferation of HL60 cells by low concentrations of 12-O-tetradecanoylphorbol-13-acetate and its relationship to the mitogenic effects of insulin

1992 • 5 citations

Expression of the kinase domain of mouse protein kinase C in E. coli.

1989 • 4 citations

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