How flies make one equal two: dosage compensation in Drosophila

Gene Action in the X-chromosome of the Mouse (Mus musculus L.)

1961 • 3,881 citations

The Genome of Drosophila Melanogaster

1992 • 3,126 citations

Histone H4 isoforms acetylated at specific lysine residues define individual chromosomes and chromatin domains in Drosophila polytene nuclei

1992 • 552 citations

Sex-lethal, a Drosophila sex determination switch gene, exhibits sex-specific RNA splicing and sequence similarity to RNA binding proteins

1988 • 461 citations

Regulation of sexual differentiation in D. melanogaster via alternative splicing of RNA from the transformer gene

1987 • 406 citations

Transformation of white locus DNA in Drosophila: Dosage compensation, zeste interaction, and position effects

1984 • 388 citations

The effect of chromosomal position on the expression of the drosophila xanthine dehydrogenase gene

1983 • 368 citations

Histone Function in Transcription

1990 • 354 citations

Decoding the nucleosome

1993 • 342 citations

Positive autoregulation of Sex-lethal by alternative splicing maintains the female determined state in Drosophila

1991 • 336 citations

Acetylated histone H4 on the male X chromosome is associated with dosage compensation in Drosophila.

1994 • 308 citations

The maleless protein associates with the X chromosome to regulate dosage compensation in drosophila

1991 • 293 citations

The Drosophila sex determination signal: how do flies count to two?

1993 • 256 citations

TWO CLOSELY LINKED MUTATIONS IN DROSOPHILA MELANOGASTER THAT ARE LETHAL TO OPPOSITE SEXES AND INTERACT WITH DAUGHTERLESS

1978 • 248 citations

Control of X chromosome transcription by the maleless gene in Drosophila

1980 • 187 citations

Multiple upstream regulatory elements control the expression of the Drosophila white gene.

1985 • 187 citations

MALE-SPECIFIC LETHAL MUTATIONS OF DROSOPHILA MELANOGASTER

1980 • 175 citations

The link between dosage compensation and sex differentiation in Drosophila melanogaster

1981 • 145 citations

Gene Dosage Compensation in Drosophila Melanogaster

1987 • 134 citations

Separable cis-acting control elements for expression of the white gene of Drosophila.

1985 • 123 citations

Dosage Compensation in Drosophila: Evidence That daughterless and Sex-lethal Control X Chromosome Activity at the Blastoderm Stage of Embryogenesis

1987 • 122 citations

The male-specific lethal-one (msl-1) gene of Drosophila melanogaster encodes a novel protein that associates with the X chromosome in males.

1993 • 105 citations

Regulation of the sex-specific binding of the maleless dosage compensation protein to the male X chromosome in Drosophila

1993 • 100 citations

Sex-specific regulation of the male-specific lethal-1 dosage compensation gene in Drosophila.

1994 • 100 citations

Decoding the nucleosome

1993 • 83 citations

The X-chromosome in the larval salivary glands of hybrids Drosophila insularis � Drosophila tropicalis

1956 • 74 citations

MALELESS, A RECESSIVE AUTOSOMAL MUTANT OF DROSOPHILA MELANOGASTER THAT SPECIFICALLY KILLS MALE ZYGOTES

1975 • 69 citations

Unwinding dosage compensation

1993 • 60 citations

Cis-acting sequences which regulate expression of the Sgs-4 glue protein gene of Drosophila.

1986 • 51 citations

Studies on the sex-specific lethals of Drosophila melanogaster. III. A third chromosome male-specific lethal mutant.

1981 • 48 citations

Effects of the maleless mutation on X and autosomal gene expression in Drosophila melanogaster.

1994 • 43 citations

Differential effects of Sex-lethal mutations on dosage compensation early in Drosophila development.

1994 • 39 citations

Upstream sequences of dosage-compensated and non-compensated alleles of the larval secretion protein gene Sgs-4 in Drosophila

1987 • 34 citations

ANALYSIS OF THE DOSAGE COMPENSATION OF A SPECIFIC TRANSCRIPT IN DROSOPHILA MELANOGASTER

1986 • 34 citations

Studies on the sex-specific lethals of Drosophila melanogaster. VII. Sex-specific lethals that do not affect dosage compensation.

1984 • 31 citations

Regulatory sequences of the Sgs-4 gene of Drosophila melanogaster analysed by P element-mediated transformation

1987 • 29 citations

X chromosome dosage compensation and its relationship to sex determination in C. elegans

1993 • 29 citations

Cloning and dosage compensation of the 6‐phosphogluconate dehydrogenase gene (Pgd⁺) of Drosophila melanogaster

1989 • 23 citations

X chromosome dosage compensation in Drosophila

1993 • 22 citations

Dosage compensation at the sgs4 locus of Drosophila melanogaster

1986 • 17 citations