Identification of a developmentally regulated protein tyrosine phosphatase in embryonic stem cells that is a marker of pluripotential epiblast and early mesoderm

Basic local alignment search tool

1990 • 87,358 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A new method for predicting signal sequence cleavage sites

1986 • 4,629 citations

Manipulating the mouse embryo: A laboratory manual

1986 • 4,548 citations

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

1995 • 1,810 citations

In situ hybridization; a practical approach

1993 • 1,247 citations

Regulation of development and differentiation by the extracellular matrix

1993 • 1,216 citations

Choice of STATs and Other Substrates Specified by Modular Tyrosine-Based Motifs in Cytokine Receptors

1995 • 992 citations

Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene

1993 • 756 citations

[25] In vitro RNA synthesis with SP6 RNA polymerase

1987 • 732 citations

Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo

1993 • 680 citations

In situ hybridization; a practical approach

1993 • 599 citations

Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene

1993 • 578 citations

A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase

1994 • 477 citations

Evidence for protein-tyrosine-phosphatase catalysis proceeding via a cysteine-phosphate intermediate.

1991 • 468 citations

Cell transformation and activation of pp60c-src by overexpression of a protein tyrosine phosphatase

1992 • 455 citations

Octamania: The POU factors in murine development

1991 • 373 citations

The SH2-containing protein-tyrosine phosphatase SH-PTP2 is required upstream of MAP kinase for early xenopus development

1995 • 330 citations

Transcriptional enhancer factor 1 disruption by a retroviral gene trap leads to heart defects and embryonic lethality in mice.

1994 • 325 citations

Culture and differentiation of embryonic stem cells

1991 • 273 citations

Dissecting the catalytic mechanism of protein-tyrosinephosphatases.

1994 • 255 citations

Receptor protein tyrosine phosphatase alpha activates pp60c-src and is involved in neuronal differentiation.

1993 • 237 citations

Maintenance of the pluripotential phenotype of embryonic stem cells through direct activation of gp130 signalling pathways

1994 • 223 citations

The role of charged amino acids in the localization of secreted and membrane proteins

1990 • 219 citations

A human transmembrane protein-tyrosine-phosphatase, PTP zeta, is expressed in brain and has an N-terminal receptor domain homologous to carbonic anhydrases.

1992 • 216 citations

Cloning of three human tyrosine phosphatases reveals a multigene family of receptor-linked protein-tyrosine-phosphatases expressed in brain.

1990 • 191 citations

A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase.

1994 • 172 citations

Complementary tissue-specific expression of LIF and LIF-receptor mRNAs in early mouse embryogenesis

1996 • 143 citations

Developmentally programmed induction of differentiation inhibiting activity and the control of stem cell populations.

1990 • 126 citations

Structure and function of SH2-domain containing tyrosine phosphatases

1993 • 118 citations

Identification of a hormonally regulated protein tyrosine phosphatase associated with bone and testicular differentiation.

1994 • 85 citations

Mouse embryo stem cells: their identification, propagation and manipulation

1992 • 80 citations

Expression of alternative forms of differentiation inhibiting activity (DIA/LIF) during murine embryogenesis and in neonatal and adult tissues

1993 • 58 citations

Genetic analyses of cell-matrix interactions in development

1994 • 53 citations

Analysis of multigene families by DNA fingerprinting of conserved domains: directed cloning of tissue-specific protein tyrosine phosphatases.

1993 • 9 citations

Maintenance of the pluripotential phenotype of embryonic stem cells through direct activation of gp130 signaling pathways

1994 • 8 citations

A technique for the direct cloning of RT-PCR fingerprinting products

1996 • 2 citations