Dissecting the catalytic mechanism of protein-tyrosinephosphatases.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains

1988 • 5,115 citations

A pharmacokinetic analysis program (multi) for microcomputer.

1981 • 2,465 citations

Protein Tyrosine Phosphatases: A Diverse Family of Intracellular and Transmembrane Enzymes

1991 • 973 citations

Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides

1992 • 684 citations

Dissecting the catalytic triad of a serine protease

1988 • 621 citations

Protein Tyrosine Phosphatase Activity of an Essential Virulence Determinant in Yersinia

1990 • 566 citations

Characterization of the major protein-tyrosine-phosphatases of human placenta.

1988 • 554 citations

PROTEIN TYROSINE PHOSPHATASES

1993 • 532 citations

Evidence for protein-tyrosine-phosphatase catalysis proceeding via a cysteine-phosphate intermediate.

1991 • 468 citations

The leukocyte common antigen (CD45): a putative receptor-linked protein tyrosine phosphatase.

1988 • 435 citations

Structural diversity and evolution of human receptor-like protein tyrosine phosphatases.

1990 • 428 citations

A Tyr/Ser protein phosphatase encoded by vaccinia virus

1991 • 403 citations

A protein-tyrosine phosphatase with sequence similarity to the SH2 domain of the protein-tyrosine kinases

1991 • 401 citations

corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso

1992 • 400 citations

Tyrosine phosphate hydrolysis of host proteins by an essential Yersinia virulence determinant.

1991 • 393 citations

Characterization of hematopoietic intracellular protein tyrosine phosphatases: description of a phosphatase containing an SH2 domain and another enriched in proline-, glutamic acid-, serine-, and threonine-rich sequences.

1992 • 367 citations

Distinct functional roles of the two intracellular phosphatase like domains of the receptor-linked protein tyrosine phosphatases LCA and LAR.

1990 • 365 citations

5′–3′ Exonucleases in phosphorothioate-based oligonucleotide-directed mutagenesis

1988 • 336 citations

1002 Protein Phosphatases?

1992 • 330 citations

cDNA isolated from a human T-cell library encodes a member of the protein-tyrosine-phosphatase family.

1989 • 313 citations

A new member of the immunoglobulin superfamily that has a cytoplasmic region homologous to the leukocyte common antigen.

1988 • 277 citations

Human placenta protein-tyrosine-phosphatase: amino acid sequence and relationship to a family of receptor-like proteins.

1989 • 276 citations

Active site labeling of the Yersinia protein tyrosine phosphatase: The determination of the pKa of the active site cysteine and the function of the conserved histidine 402

1993 • 276 citations

Expression, purification, and physicochemical characterization of a recombinant Yersinia protein tyrosine phosphatase.

1992 • 228 citations

Cloning and expression of a protein-tyrosine-phosphatase.

1990 • 215 citations

Identification, cloning, and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to cytoskeletal protein 4.1.

1991 • 198 citations

Substrate specificity of the protein tyrosine phosphatases.

1993 • 189 citations

Antibody Catalysis of a Disfavored Chemical Transformation

1993 • 177 citations

The plasmid‐encoded Yop2b protein of Yersinia pseudotuberculosis is a virulence determinant regulated by calcium and temperature at the level of transcription

1988 • 172 citations

Cloning, bacterial expression, purification, and characterization of the cytoplasmic domain of rat LAR, a receptor-like protein tyrosine phosphatase.

1991 • 132 citations

A thousand and two protein tyrosine phosphatases

1992 • 119 citations

Characterization of Hematopoietic Intracellular Protein Tyrosine Phosphatases: Description of a Phosphatase Containing an SH2 Domain and Another Enriched in Proline-, Glutamic Acid-, Serine-, and Threonine-Rich Sequences

1992 • 91 citations

Analysis of a spatially regulated phosphotyrosine phosphatase identifies tyrosine phosphorylation as a key regulatory pathway in Dictyostelium

1992 • 81 citations

Nucleotide sequence and transcription analysis of yop51 from Yersinia enterocolitica W22703

1988 • 77 citations

Mutational analysis of CD45. A leukocyte-specific protein tyrosine phosphatase.

1992 • 74 citations

Cloning and expression of a yeast protein tyrosine phosphatase

1991 • 66 citations

Active site labeling of a receptor-like protein tyrosine phosphatase.

1992 • 63 citations

Catalytic domains of the LAR and CD45 protein tyrosine phosphatases from Escherichia coli expression systems: purification and characterization for specificity and mechanism

1992 • 61 citations

Isolation and characterization of temperature-sensitive and thermostable mutants of the human receptor-like protein tyrosine phosphatase LAR

1991 • 58 citations

Cleavage of phosphorothioate-substituted DNA by restriction endonucleases.

1984 • 52 citations

Isolation and characterization of a second protein tyrosine phosphatase gene, PTP2, from Saccharomyces cerevisiae.

1992 • 35 citations

Mechanistic studies of a tyrosine-dependent catalytic antibody

1991 • 35 citations

Antibody-Catalyzed Rearrangement of the Peptide Bond

1992 • 28 citations

ChemInform Abstract: Antibody‐Catalyzed Rearrangement of the Peptide Bond.

1993 • 1 citations