Expression of alternative forms of differentiation inhibiting activity (DIA/LIF) during murine embryogenesis and in neonatal and adult tissues

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Establishment in culture of pluripotential cells from mouse embryos

1981 • 8,424 citations

Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells.

1981 • 5,629 citations

Purification of Mouse Immunoglobulin Heavy‐Chain Messenger RNAs from Total Myeloma Tumor RNA

1980 • 2,696 citations

Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor

1992 • 2,004 citations

Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells

1988 • 2,004 citations

Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides

1988 • 1,848 citations

Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines

1984 • 1,518 citations

Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130

1989 • 1,411 citations

Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture

1992 • 1,205 citations

The IL-6 Signal Transducer, gp130: an Pncostatin M Receptor and Affinity Converter for the LIF Receptor

1992 • 897 citations

Interleukin-6 and Its Receptor: A Paradigm for Cytokines

1992 • 889 citations

[25] In vitro RNA synthesis with SP6 RNA polymerase

1987 • 732 citations

CNTF and LIF act on neuronal cells via shared signaling pathways that involve the IL-6 signal transducing receptor component gp130

1992 • 693 citations

Leukemia inhibitory factor receptor is structurally related to the IL-6 signal transducer, gp130.

1991 • 587 citations

Molecular cloning and expression of cDNA encoding a murine myeloid leukaemia inhibitory factor (LIF).

1987 • 567 citations

The Cholinergic Neuronal Differentiation Factor from Heart Cells Is Identical to Leukemia Inhibitory Factor

1989 • 557 citations

Uterine expression of leukemia inhibitory factor coincides with the onset of blastocyst implantation.

1991 • 507 citations

Effect of Steel factor and leukaemia inhibitory factor on murine primordial germ cells in culture

1991 • 459 citations

Buffalo rat liver cells produce a diffusible activity which inhibits the differentiation of murine embryonal carcinoma and embryonic stem cells

1987 • 403 citations

Oncostatin M is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6.

1991 • 372 citations

LIF: lots of interesting functions

1992 • 341 citations

Derivation of mouse intestinal crypts from single progenitor cells

1985 • 330 citations

Diffusible factors in vertebrate embryonic induction

1992 • 327 citations

Purification of a factor inducing differentiation of mouse myeloid leukemic M1 cells from conditioned medium of mouse fibroblast L929 cells.

1984 • 318 citations

Fatal syndrome in mice engrafted with cells producing high levels of the leukemia inhibitory factor.

1989 • 280 citations

Leukaemia inhibitory factor is identical to the myeloid growth factor human interleukin for DA cells

1988 • 273 citations

Hepatocyte-stimulating factor III shares structural and functional identity with leukemia-inhibitory factor.

1989 • 272 citations

Differentiation inhibiting activity is produced in matrix-associated and diffusible forms that are generated by alternate promoter usage

1990 • 271 citations

Leukemia inhibitory factor is expressed by the preimplantation uterus and selectively blocks primitive ectoderm formation in vitro.

1992 • 254 citations

Effects of injected leukemia inhibitory factor on hematopoietic and other tissues in mice

1990 • 226 citations

Generation of sensory neurons is stimulated by leukemia inhibitory factor.

1991 • 208 citations

Functional inhibition of hematopoietic and neurotrophic cytokines by blocking the interleukin 6 signal transducer gp130.

1992 • 206 citations

Leukemia inhibitory factor: A biological perspective

1991 • 167 citations

Purification of a lipoprotein lipase-inhibiting protein produced by a melanoma cell line associated with cancer cachexia

1989 • 164 citations

A major binding protein for leukemia inhibitory factor in normal mouse serum: identification as a soluble form of the cellular receptor.

1992 • 146 citations

Leukemia inhibitory factor differentiation-inhibiting activity/human interleukin for DA cells augments proliferation of human hematopoietic stem cells

1990 • 133 citations

Developmentally programmed induction of differentiation inhibiting activity and the control of stem cell populations.

1990 • 126 citations

Pituitary follicular cells secrete an inhibitor of aortic endothelial cell growth: identification as leukemia inhibitory factor.

1992 • 122 citations

Differentiation inhibiting activity () and mouse development

1992 • 121 citations

Leukemia inhibitory factor sustains the survival of mouse primordial germ cells cultured on TM4 feeder layers

1991 • 116 citations

Clonal analysis of the actions of the murine leukemia inhibitory factor on leukemic and normal murine hemopoietic cells.

1988 • 107 citations

Localization of cholinergic differentiation factor/leukemia inhibitory factor mRNA in the rat brain and peripheral tissues.

1991 • 83 citations

Mouse embryo stem cells: their identification, propagation and manipulation

1992 • 80 citations

LIF, the ES-cell inhibition factor, reversibly blocks nephrogenesis in cultured mouse kidney rudiments

1991 • 61 citations

Leukemia inhibitory factor (LIF) inhibits basal bone resorption in fetal rat long bone cultures

1990 • 58 citations

Leukemia inhibitory factor improves survival of retroviral vector-infected hematopoietic stem cells in vitro, allowing efficient long-term expression of vector-encoded human adenosine deaminase in vivo.

1991 • 50 citations

Epidermal keratinocyte stem cells: their maintenance and regulation

1992 • 25 citations