Characterization of the Interaction between the Acidic Activation Domain of VP16 and the RNA Polymerase II Initiation Factor TFIIB

Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region

1985 • 1,244 citations

Transcriptional activation: A complex puzzle with few easy pieces

1994 • 1,112 citations

A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II

1994 • 1,064 citations

Five intermediate complexes in transcription initiation by RNA polymerase II

1989 • 1,033 citations

Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of Yeast

1986 • 946 citations

Deletion analysis of GAL4 defines two transcriptional activating segments

1987 • 898 citations

Direct and selective binding of an acidic transcriptional activation domain to the TATA-box factor TFIID

1990 • 620 citations

Molecular cloning and functional analysis of Drosophila TAF110 reveal properties expected of coactivators

1993 • 589 citations

An RNA polymerase II holoenzyme responsive to activators

1994 • 586 citations

Mechanism of action of an acidic transcriptional activator in vitro

1991 • 557 citations

Crystal structure of a TFIIB–TBP–TATA-element ternary complex

1995 • 542 citations

Transcription factor ATF interacts with the TATA factor to facilitate establishment of a preinitiation complex

1988 • 488 citations

Factors involved in specific transcription by mammalian RNA polymerase II: purification, genetic specificity, and TATA box-promoter interactions of TFIID.

1988 • 477 citations

A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast

1993 • 465 citations

Critical Structural Elements of the VP16 Transcriptional Activation Domain

1991 • 461 citations

Genetic isolation of ADA2: A potential transcriptional adaptor required for function of certain acidic activation domains

1992 • 446 citations

p53 Transcriptional Activation Mediated by Coactivators TAF _II 40 and TAF _II 60

1995 • 438 citations

Drosophila TAFII40 interacts with both a VP16 activation domain and the basal transcription factor TFIIB

1993 • 418 citations

Initiation of Transcription by RNA Polymerase II: A Multi-step Process

1993 • 390 citations

Adenovirus E1A activation domain binds the basic repeat in the TATA box transcription factor

1991 • 381 citations

Binding of general transcription factor TFIIB to an acidic activating region

1991 • 377 citations

Structure and function of transcriptional activation domains

1995 • 376 citations

Reduced binding of TFIID to transcriptionally compromised mutants of VP16

1991 • 362 citations

Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes

1994 • 361 citations

Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53.

1994 • 355 citations

Members of the steroid hormone receptor superfamily interact with TFIIB (S300-II).

1992 • 354 citations

Interaction of human thyroid hormone receptor beta with transcription factor TFIIB may mediate target gene derepression and activation by thyroid hormone.

1993 • 328 citations

Activation of class II gene transcription by regulatory factors is potentiated by a novel activity

1991 • 318 citations

Eukaryotic activators function during multiple steps of preinitiation complex assembly

1993 • 311 citations

Cloning of a human gene encoding the general transcription initiation factor IIB

1991 • 274 citations

Species-specific interaction of the glutamine-rich activation domains of Sp1 with the TATA box-binding protein.

1994 • 266 citations

Contact with a component of the polymerase II holoenzyme suffices for gene activation

1995 • 262 citations

Pattern of aromatic and hydrophobic amino acids critical for one of two subdomains of the VP16 transcriptional activator.

1993 • 261 citations

Isolation and characterization of the Drosophila gene encoding the TATA box binding protein, TFIID

1990 • 254 citations

The Zta trans-activator protein stabilizes TFIID association with promoter DNA by direct protein-protein interaction.

1991 • 249 citations

The p53 Activation Domain Binds the TATA Box-Binding Polypeptide in Holo-TFIID, and a Neighboring p53 Domain Inhibits Transcription

1993 • 246 citations

Multiple functional domains of human transcription factor IIB: distinct interactions with two general transcription factors and RNA polymerase II.

1993 • 229 citations

Interaction between an acidic activator and transcription factor TFIIB is required for transcriptional activation

1993 • 225 citations

Direct interaction between the transcriptional activation domain of human p53 and the TATA box-binding protein.

1993 • 209 citations

The yeast SUA7 gene encodes a homolog of human transcription factor TFIIB and is required for normal start site selection in vivo

1992 • 200 citations

A mammalian RNA polymerase II holoenzyme containing all components required for promoter-specific transcription initiation

1995 • 194 citations

Structure and associated DNA-helicase activity of a general transcription initiation factor that binds to RNA polymerase II

1989 • 193 citations

Yeast TATA-box transcription factor gene.

1989 • 191 citations

Connecting a promoter-bound protein to TBP bypasses the need for a transcriptional activation domain

1995 • 188 citations

Activation of yeast polymerase II transcription by herpesvirus VP16 and GAL4 derivatives in vitro.

1989 • 187 citations

Factors Involved in Specific Transcription by Mammalian RNA Polymerase II: Purification, Genetic Specificity, and TATA Box-Promoter Interactions of TFIID

1988 • 184 citations

Association between proto-oncoprotein Rel and TATA-binding protein mediates transcriptional activation by NF-κB

1993 • 168 citations

GAL4 Interacts with TATA-Binding Protein and Coactivators

1995 • 164 citations

Stimulation of RNA polymerase II transcription initiation by recruitment of TBP in vivo

1995 • 161 citations

TATA-binding protein and the retinoblastoma gene product bind to overlapping epitopes on c-Myc and adenovirus E1A protein.

1993 • 146 citations

The retinoblastoma protein binds E2F residues required for activation in vivo and TBP bindingin vitro

1993 • 131 citations

Increased Recruitment of TATA-Binding Protein to the Promoter by Transcriptional Activation Domains in Vivo

1994 • 114 citations

Proline-rich activator CTF1 targets the TFIIB assembly step during transcriptional activation.

1994 • 114 citations

Binding of Basal Transcription Factor TFIIH to the Acidic Activation Domains of VP16 and p53

1994 • 112 citations

Effects of activation-defective TBP mutations on transcription initiation in yeast

1994 • 110 citations

Initiation of transcription by RNA polymerase II is limited by melting of the promoter DNA in the region immediately upstream of the initiation site.

1994 • 110 citations

Yeast ADA2 protein binds to the VP16 protein activation domain and activates transcription.

1994 • 109 citations

The p53 activation domain binds the TATA box-binding polypeptide in Holo-TFIID, and a neighboring p53 domain inhibits transcription.

1993 • 108 citations

Functional Interaction of the v-Rel and c-Rel Oncoproteins with the TATA-Binding Protein and Association with Transcription Factor IIB

1993 • 102 citations

A cDNA encoding RAP74, a general initiation factor for transcription by RNA polymerase II

1992 • 98 citations

The role of activators in assembly of RNA polymerase II transcription complexes

1994 • 86 citations

Transcriptional Activation by the Acidic Domain of Vmw65 Requires the Integrity of the Domain and Involves Additional Determinants Distinct from Those Necessary for TFIIB Binding

1993 • 65 citations

Species-Specific Interaction of the Glutamine-Rich Activation Domains of Spl with the TATA Box-Binding Protein

1994 • 59 citations

Activation of Yeast Polymerase II Transcription by Herpesvirus VP16 and GAL4 Derivatives In Vitro

1989 • 56 citations

Transcription Factor TFIIB Sites Important for Interaction with Promoter-Bound TFIID

1993 • 52 citations

Functional analysis of Drosophila transcription factor IIB.

1992 • 49 citations

Modeling eukaryotic transcriptional activation

1994 • 47 citations

The acidic activation domain of the Epstein-Barr virus transcription factor R interacts in vitro with both TBP and TFIIB and is cell-specifically potentiated by a proline-rich region.

1993 • 47 citations

The ability to associate with activation domains in vitro is not required for the TATA box-binding protein to support activated transcription in vivo.

1995 • 39 citations

Functional interaction of the v-Rel and c-Rel oncoproteins with the TATA-binding protein and association with transcription factor IIB.

1993 • 32 citations

Promoter-dependent Photocross-linking of the Acidic Transcriptional Activator E2F-1 to the TATA-binding Protein

1995 • 30 citations

Transcriptional activation by the acidic domain of Vmw65 requires the integrity of the domain and involves additional determinants distinct from those necessary for TFIIB binding.

1993 • 28 citations