Endothelium-derived relaxing factor

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1980 • 12,033 citations

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

INOSITOL TRISPHOSPHATE AND DIACYLGLYCEROL: TWO INTERACTING SECOND MESSENGERS

1987 • 3,302 citations

Paradoxical Vasoconstriction Induced by Acetylcholine in Atherosclerotic Coronary Arteries

1986 • 2,422 citations

Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor

1986 • 2,416 citations

Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats.

1977 • 2,105 citations

Calcitonin gene-related peptide is a potent vasodilator

1985 • 2,050 citations

Role of endothelium in responses of vascular smooth muscle.

1983 • 1,975 citations

Flow-induced release of endothelium-derived relaxing factor

1986 • 1,379 citations

Is there a basis for distinguishing two types of P2-purinoceptor?

1985 • 1,353 citations

Selective blockade of endothelium-dependent and glyceryl trinitrate-induced relaxation by hemoglobin and by methylene blue in the rabbit aorta.

1985 • 1,266 citations

Proposals for the classification and nomenclature of functional receptors for 5-hydroxytryptamine

1986 • 1,255 citations

Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor

1986 • 1,211 citations

Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical.

1987 • 1,182 citations

Crucial role of endothelium in the vasodilator response to increased flow in vivo.

1986 • 991 citations

Agonist-induced endothelium-dependent relaxation in rat thoracic aorta may be mediated through cGMP.

1983 • 949 citations

The Role of Endothelium in the Responses of Vascular Smooth Muscle to Drugs

1984 • 937 citations

Correlation between nitric oxide formation during degradation of organic nitrates and activation of guanylate cyclase

1987 • 896 citations

Endothelium-dependent contractions to acetylcholine in the aorta of the spontaneously hypertensive rat.

1986 • 892 citations

Endothelium-dependent relaxation of coronary arteries by noradrenaline and serotonin

1983 • 855 citations

Comparative pharmacology of endothelium‐derived relaxing factor, nitric oxide and prostacyclin in platelets

1987 • 824 citations

The role of nitric oxide and cGMP in platelet adhesion to vascular endothelium

1987 • 765 citations

Single stretch-activated ion channels in vascular endothelial cells as mechanotransducers?

1987 • 703 citations

The Pharmacological and Physiological Role of Cyclic GMP in Vascular Smooth Muscle Relaxation

1985 • 685 citations

Macrophage synthesis of nitrite, nitrate, and N-nitrosamines: precursors and role of the respiratory burst.

1987 • 678 citations

The importance of phospholipase-A2 in prostaglandin biosynthesis

1976 • 647 citations

Modulation of Vascular Smooth Muscle Contraction by the Endothelium

1986 • 643 citations

Evidence for the inhibitory role of guanosine 3', 5'-monophosphate in ADP-induced human platelet aggregation in the presence of nitric oxide and related vasodilators

1981 • 629 citations

Endothelium-dependent relaxation in rat aorta may be mediated through cyclic GMP-dependent protein phosphorylation

1983 • 623 citations

The nature of endothelium-derived vascular relaxant factor

1984 • 591 citations

Heterogeneous behavior of the canine arterial and venous wall. Importance of the endothelium.

1982 • 545 citations

Endothelium‐dependent inhibition of platelet aggregation

1986 • 540 citations

Effect of hypercholesterolemia on vascular reactivity in the rabbit. I. Endothelium-dependent and endothelium-independent contractions and relaxations in isolated arteries of control and hypercholesterolemic rabbits.

1986 • 535 citations

Suppression of atherogenesis in cholesterol-fed rabbit treated with nifedipine.

1981 • 437 citations

The Pharmacology of Vascular Smooth Muscle

1996 • 435 citations

Role of endothelial cells in relaxation of isolated arteries by bradykinin.

1982 • 420 citations

Role of endothelium in dilator responses of spontaneously hypertensive rat arteries.

1983 • 414 citations

Atherosclerosis impairs endothelium-dependent vascular relaxation to acetylcholine and thrombin in primates.

1986 • 406 citations

Activation of purified soluble guanylate cyclase by endothelium-derived relaxing factor from intrapulmonary artery and vein: stimulation by acetylcholine, bradykinin and arachidonic acid.

1986 • 397 citations

The kinetics and equilibria of the reactions of nitric oxide with sheep haemoglobin

1957 • 385 citations

Depression of contractile responses in rat aorta by spontaneously released endothelium-derived relaxing factor.

1986 • 381 citations

Role of the intima in cholinergic and purinergic relaxation of isolated canine femoral arteries.

1981 • 380 citations

Oxygen-derived free radicals, endothelium, and responsiveness of vascular smooth muscle

1986 • 380 citations

The loss of endothelium-dependent vascular relaxation in hypertension.

1986 • 372 citations

Coronary Artery Spasm Induced in Atherosclerotic Miniature Swine

1983 • 372 citations

Flow-dependent, endothelium-mediated dilation of epicardial coronary arteries in conscious dogs: effects of cyclooxygenase inhibition.

1984 • 367 citations

Endothelium‐derived relaxing factor inhibits in vitro platelet aggregation

1987 • 367 citations

Inhibitory Role of the Endothelium in the Response of Isolated Coronary Arteries to Platelets

1983 • 353 citations

Endothelium-dependent inhibitory effects of acetylcholine, adenosine triphosphate, thrombin and arachidonic acid in the canine femoral artery.

1982 • 345 citations

Coronary Vascular Reactivity After Acute Myocardial Ischemia

1982 • 336 citations

Physiology of Smooth Muscle

1977 • 325 citations

Endothelial Cells as Mediators of Vasodilation of Arteries

1984 • 322 citations

EDRF coordinates the behaviour of vascular resistance vessels

1987 • 318 citations

Low-density lipoproteins inhibit endothelium-dependent relaxation in rabbit aorta

1987 • 310 citations

The role of protein kinase C in the regulation of ion channels and neurotransmitter release

1987 • 310 citations

Bradykinin-induced increases in cytosolic calcium and ionic currents in cultured bovine aortic endothelial cells.

1987 • 292 citations

Cyclic guanosine monophosphate inhibition of contraction may be mediated through inhibition of phosphatidylinositol hydrolysis in rat aorta.

1986 • 282 citations

Flow-Dependent, Endothelium-Mediated Dilation of Epicardial Coronary Arteries in Conscious Dogs

1984 • 279 citations

Thrombosis and haemostasis

1988 • 263 citations

Anoxia and endothelium‐dependent reactivity of the canine femoral artery.

1983 • 259 citations

Hormone and neurotransmitter receptors in an established vascular endothelial cell line.

1976 • 257 citations

Association between cyclic GMP accumulation and acetylcholine-elicited relaxation of bovine intrapulmonary artery.

1984 • 257 citations

Role of the endothelium in the vasodilator response of rat thoracic aorta to histamine

1983 • 249 citations

Activation of guanylate cyclase by superoxide dismutase and hydroxyl radical: a physiological regulator of guanosine 3',5'-monophosphate formation.

1977 • 238 citations

The requirement for endothelial cells in the relaxation of arteries by acetylcholine and some other vasodilators

1981 • 231 citations

Release and properties of endothelium‐derived relaxing factor (EDRF) from endothelial cells in culture

1985 • 230 citations

Endothelium-induced relaxation by acetylcholine associated with larger rises in cyclic GMP in coronary arterial strips.

1982 • 228 citations

Bioassay of prostacyclin and endothelium‐derived relaxing factor (EDRF) from porcine aortic endothelial cells

1997 • 226 citations

Acetylcholine and Bradykinin Relax Intrapulmonary Arteries by Acting on Endothelial Cells: Role in Lung Vascular Diseases

1981 • 226 citations

Enhanced responsiveness of rat isolated aorta to clonidine after removal of the endothelial cells

1984 • 225 citations

Bradykinin stimulation of inositol polyphosphate production in porcine aortic endothelial cells.

1986 • 225 citations

Preservation of endothelium-dependent vascular relaxation in cholesterol-fed rabbit by treatment with the calcium blocker PN 200110.

1986 • 219 citations

Mechanism of action of some inhibitors of endothelium-derived relaxing factor.

1986 • 218 citations

Coronary Arteries of Cardiac Patients Are Hyperreactive and Contain Stores of Amines: A Mechanism for Coronary Spasm

1984 • 213 citations

Activation of cerebral guanylate cyclase by nitric oxide

1977 • 212 citations

Ultrastructural localization of choline acetyltransferase in vascular endothelial cells in rat brain

1985 • 204 citations

Calcium- and endothelial-mediated vascular smooth muscle relaxation in rabbit aorta.

1982 • 202 citations

Exogenous ATP raises cytoplasmic free calcium in fura‐2 loaded piglet aortic endothelial cells

1986 • 200 citations

ANTAGONIST DISCRIMINATION BETWEEN GANGLIONIC AND ILEAL MUSCARINIC RECEPTORS

1997 • 199 citations

Bioassay of prostacyclin and endothelium‐derived relaxing factor (EDRF) from porcine aortic endothelial cells

1986 • 197 citations

5-Hydroxytryptamine can mediate endothelium-dependent relaxation of coronary arteries

1983 • 194 citations

ANTAGONIST DISCRIMINATION BETWEEN GANGLIONIC AND ILEAL MUSCARINIC RECEPTORS

1980 • 191 citations

Decreased Endothelium-dependent Relaxation in New Zealand Genetic Hypertensive Rats

1984 • 189 citations

Nitric oxide (NO) formation from nitrovasodilators occurs independently of hemoglobin or non-heme iron

1987 • 183 citations

Polyphosphoinositide hydrolysis in endothelial cells and carotid artery segments. Bradykinin-2 receptor stimulation is calcium-independent.

1986 • 181 citations

Endothelial cell damage and thrombus formation after partial arterial constriction: relevance to the role of coronary artery spasm in the pathogenesis of myocardial infarction.

1981 • 180 citations

The mechanism of cGMP-induced relaxation in vascular smooth muscle

1985 • 180 citations

Intestinal vasodilation by epoxyeicosatrienoic acids: arachidonic acid metabolites produced by a cytochrome P450 monooxygenase.

1987 • 176 citations

Increased free calcium in endothelial cells under stimulation with adenine nucleotides

1986 • 171 citations

5-HT: The Enigma Variations

1987 • 167 citations

Endothelium‐dependent relaxation of the pig aorta: relationship to stimulation of ⁸⁶Rb efflux from isolated endothelial cells

1983 • 166 citations

Recovery of prostacyclin production by de-endothelialized rabbit aorta. Critical role of neointimal smooth muscle cells.

1981 • 166 citations

The mechanisms by which haemoglobin inhibits the relaxation of rabbit aorta induced by nitrovasodilators, nitric oxide, or bovine retractor penis inhibitory factor

1986 • 165 citations

Enhancement of alpha-1 and alpha-2 adrenergic agonist-induced vasoconstriction by removal of endothelium in rat aorta.

1985 • 163 citations

The end of the quest?

1987 • 160 citations

Endothelium-dependent modulation of cGMP levels and intrinsic smooth muscle tone in isolated bovine intrapulmonary artery and vein.

1987 • 157 citations

Bioassay of endothelium-derived relaxing factor(s): inactivation by catecholamines

1985 • 154 citations

Endothelium-dependent and independent relaxation of aortic rings from hypertensive rats

1986 • 154 citations

Regulation of the L-type calcium channel

1987 • 147 citations

Blockade of endothelium-dependent and glyceryl trinitrate-induced relaxation of rabbit aorta by certain ferrous hemoproteins.

1985 • 145 citations

Adenine nucleotides, serotonin, and endothelium-dependent relaxations to platelets

1985 • 143 citations

Production of endothelium derived relaxant factor is dependent on oxidative phosphorylation and extracellular calcium

1986 • 143 citations

α₂‐Adrenoceptors and endothelium‐dependent relaxation in canine large arteries

1986 • 142 citations

Comparative pharmacology of EDRF and nitric oxide on vascular strips

1987 • 140 citations

Influence of the vascular endothelium on agonist‐induced contractions and relaxations in rat aorta

1986 • 138 citations

Reactivity of the Canine Isolated Internal Mammary Artery, Saphenous Vein, and Coronary Artery to Constrictor and Dilator Substances

1988 • 137 citations

Endothelium‐derived relaxing factor alters calcium fluxes in rabbit aorta: a cyclic guanosine monophosphate‐mediated effect.

1986 • 136 citations

Mechanism of protection from atherosclerosis by verapamil in the cholesterol-fed rabbit

1984 • 133 citations

Effects of bradykinin and angiotensin II on intracellular Ca2+ dynamics in endothelial cells

1987 • 133 citations

Removal of the endothelium potentiates canine large coronary artery constrictor responses to 5-hydroxytryptamine in vivo.

1985 • 126 citations

Vasodilatation by acetylcholine is endothelium‐dependent: a study by sonomicrometry in canine femoral artery in vivo.

1983 • 125 citations

Vascular Neuroeffector Mechanisms

1984 • 125 citations

Direct interaction of mepacrine with erythrocyte and platelet membrane phospholipid.

1982 • 124 citations

Electrical responses of smooth muscle cells during cholinergic vasodilation in the rabbit saphenous artery.

1987 • 124 citations

Endothelium‐dependent relaxation induced by angiotensin II and histamine in isolated arteries of dog

1984 • 122 citations

Evidence for Endothelium-Dependent Vasodilation of Resistance Vessels by Acetylcholine

1987 • 121 citations

Endothelium-derived vascular relaxing factor.

1985 • 120 citations

Role of the endothelium in the control of vascular smooth muscle function.

1982 • 119 citations

Different P2-purinergic receptor subtypes of endothelium and smooth muscle in canine blood vessels.

1987 • 117 citations

Biosynthesis and metabolism of 15-hydroperoxy-5,8,11,13-eicosatetraenoic acid by human umbilical vein endothelial cells.

1984 • 117 citations

In vivo EDRF activity influences platelet function

1988 • 116 citations

Mechanisms of endothelium-dependent vascular smooth muscle relaxation

1985 • 115 citations

Species-dependent differences in the nature of endothelium-derived vascular relaxing factor

1984 • 114 citations

Endothelium and the vasodilator action of rat calcitonin gene‐related peptide (CGRP)

1987 • 113 citations

Release of endothelium-derived relaxing factor from human umbilical vessels.

1987 • 112 citations

Endothelium-Dependent Reactivity in Resistance Vessels

2015 • 112 citations

Hydroxyl radical mediates the endothelium-dependent relaxation produced by bradykinin in mouse cerebral arterioles.

1987 • 110 citations

Haptoglobin-haemoglobin complex in human plasma inhibits endothelium dependent relaxation: evidence that endothelium derived relaxing factor acts as a local autocoid

1986 • 110 citations

Inhibition by Acetylcholine of Adrenergic Neurotransmission in Vascular Smooth Muscle

1974 • 110 citations

Cyclic GMP mediates neurogenic relaxation in the bovine retractor penis muscle

1984 • 108 citations

A morphologic and permeability study of luminal smooth muscle cells after arterial injury in the rat.

1978 • 105 citations

Two dilatory mechanisms of anti-anginal drugs on epicardial coronary arteries in vivo: indirect, flow-dependent, endothelium-mediated dilation and direct smooth muscle relaxation.

1983 • 103 citations

Mechanism of histamine actions in human coronary arteries.

1987 • 102 citations

Role of endothelium in the contractile response of rat aorta to α-adrenoceptor agonists

1985 • 101 citations

Endothelium-dependent responses to platelets and serotonin in spontaneously hypertensive rats.

1986 • 100 citations

Use of endothelium cultured on microcarriers as a model for the microcirculation.

1982 • 98 citations

Differential classification of vascular smooth muscle and endothelial cell 5‐HT receptors by use of tryptamine analogues

1987 • 97 citations

Endothelium-dependent relaxation of rabbit aorta. I. Relaxation stimulated by arachidonic acid.

1983 • 96 citations

Role of calcium in endothelium-dependent relaxation of arterial smooth muscle

1987 • 96 citations

Effects of nitroprusside and 8-bromo-cyclic GMP on the contractile activity of the rat aorta.

1983 • 94 citations

Contraction and relaxation of the retractor penis muscle and the penile artery of the bull.

1974 • 91 citations

Endothelium-Dependent Flow-Induced Dilation of Canine Femoral and Saphenous Arteries

1986 • 90 citations

Effect of lipid feeding on endothelium dependent relaxation in rabbit aortic preparations

1987 • 87 citations

Effects of Glyceryl Trinitrate on Endothelium-Dependent and -Independent Relaxation and Cyclic GMP Levels in Rat Aorta and Human Coronary Artery

1987 • 83 citations

Endothelium-dependent relaxation in isolated human arteries and veins

1987 • 82 citations

Nature of endothelium-derived relaxing factor: are there two relaxing mediators?

1987 • 82 citations

Endothelium-dependent and nitrovasodilator-induced activation of cyclic GMP-dependent protein kinase in rat aorta.

1983 • 80 citations

Inhibitors of acyl-coenzyme A:lysolecithin acyltransferase activate the production of endothelium-derived vascular relaxing factor.

1986 • 80 citations

Reactions of Methæmo-Globin and Catalase with Peroxides and Hydrogen Donors

1954 • 79 citations

Endothelium-derived relaxing factor is identified as nitric oxide

1987 • 78 citations

Blockade of endothelium-dependent relaxation by the amiloride analog dichlorobenzamil: possible role of Na+/Ca++ exchange in the release of endothelium-derived relaxant factor.

1985 • 78 citations

Cytochrome P-450-dependent monooxygenase activity and endothelial-dependent relaxations induced by arachidonic acid.

1986 • 77 citations

Differential selectivity of endothelium‐derived relaxing factor and nitric oxide in smooth muscle

1987 • 76 citations

Endothelium-Dependent Contractions in Arteries and Veins

1987 • 76 citations

Calcium- and endothelial-mediated vascular smooth muscle relaxation in rabbit aorta

1982 • 76 citations

Effects of Cytochrome P-450 Inhibitors on Endothelium-Dependent Relaxation in Rabbit Aorta

1984 • 76 citations

Arachidonic acid metabolism in a cell suspension isolated from rabbit renal outer medulla.

1984 • 75 citations

EDRF and cyclic GMP control gating of receptor-operated calcium channels in vascular smooth muscle

1986 • 75 citations

Possible role for cyclic GMP in endothelium-dependent relaxation of rabbit aorta by acetylcholine. Comparison with nitroglycerin.

1983 • 74 citations

Endothelium-dependent relaxation of rabbit aorta. II. Inhibition of relaxation stimulated by methacholine and A23187 with antagonists of arachidonic acid metabolism.

1983 • 74 citations

Endothelial mediated inhibition of contraction and increase in cyclic GMP levels evoked by the α‐adrenoceptor agonist B‐HT 920 in rat isolated aorta

1984 • 73 citations

The endothelium-dependent vasodilator effect of acetylcholine: Characterization of the endothelial relaxing factor with inhibitors of arachidonic acid metabolism

1984 • 73 citations

Cholinergic mechanisms in human coronary artery preparations: implications of species differences.

1985 • 72 citations

Immediate and long-term effects of angioplasty-balloon dilation on normal rabbit iliac artery.

1986 • 72 citations

Characterization of vascular relaxant factor released from cultured endothelial cells.

1987 • 71 citations

Presence of cytochrome P-450-dependent monooxygenase in intimal cells of the hog aorta.

1985 • 70 citations

Purification and properties of a protein required for sodium azide activation of guanylate cyclase.

1977 • 68 citations

Nature of Endothelium-Derived Relaxing Factor: Are There Two Relaxing Mediators?

1987 • 68 citations

Stimulation of soluble guanylate cyclase by endothelium-derived relaxing factor from cultured endothelial cells

1987 • 68 citations

Endothelial mechanism in the vascular action of hydralazine.

1983 • 66 citations

Neurogenic muscarinic vasodilation in the cat. An example of endothelial cell-independent cholinergic relaxation.

1985 • 64 citations

A phorbol ester inhibits the release of endothelium-derived relaxing factor

1987 • 63 citations

Relaxation of intrapulmonary artery and vein by nitrogen oxide-containing vasodilators and cyclic GMP.

1984 • 61 citations

Relaxing and Contracting Factors

1988 • 59 citations

Calcium regulation in vascular smooth muscle contractility

1987 • 58 citations

Stimulation of endothelial prostacyclin production plays no role in endothelium‐dependent relaxation of the pig aorta

1983 • 58 citations

Short- and long-term interactions of endothelium and vascular smooth muscle in coculture: effects on cyclic GMP production.

1986 • 57 citations

Reversal of acetycholine-induced coronary resistance vessel dilation by hemoglobin

1987 • 57 citations

Relaxant effects of ATP and adenosine on canine large and small coronary arteries in vitro

1987 • 55 citations

A smooth muscle inhibitory material from the bovine retractor penis and rat anococcygeus muscles.

1980 • 55 citations

Evidence for endothelium-derived relaxing factor in cultured cells.

1985 • 55 citations

Calcium Channel Activation Does Not Increase Release of Endothelial-Derived Relaxant Factors (EDRF) in Rat Aorta Although Tonic Release of EDRF May Modulate Calcium Channel Activity in Smooth Muscle

1986 • 53 citations

Venous and arterial endothelia: different dilator abilities in dog vessels.

1987 • 53 citations

Evidence for the role of endothelium-derived relaxing factor in acetylcholine-induced vasodilatation in the intact lung.

1987 • 52 citations

EXTRACTION FROM OX RETRACTOR PENIS OF AN INHIBITORY SUBSTANCE WHICH MIMICS ITS ATROPINE‐RESISTANT NEUROGENIC RELAXATION

1975 • 51 citations

Characterization of muscarinic receptors of the rabbit ear artery smooth muscle and endothelium.

1986 • 51 citations

Endothelium-dependent vasodilation by melittin: are lipoxygenase products involved?

1985 • 51 citations

Endothelium and asymmetrical responses of the coronary arterial wall

1984 • 50 citations

Mode of action of quinacrine on the acetylcholine receptor ionic channel complex.

1979 • 49 citations

Anion exchange resins discriminate between nitric oxide and EDRF

1987 • 48 citations

Insensitivity of calcium‐dependent endothelial stimulation in rat isolated aorta to the calcium entry blocker, flunarizine

1985 • 47 citations

Endothelial-dependent relaxant effects of vaso-active intestinal polypeptide and arachidonic acid in rat aortic strips

1984 • 47 citations

Remodeling of the rat aortic endothelial layer during experimental hypertension. Changes in replication rate, cell density, and surface morphology.

1983 • 46 citations

Role of sodium-calcium exchange and effects of calcium entry blockers on endothelial-mediated responses in rat isolated aorta.

1986 • 46 citations

Acetylcholine induced endothelial-dependent vasodilation increases as artery diameter decreases in the rabbit ear

1985 • 46 citations

Pathogenesis of coronary artery spasm in miniature swine with regional intimal thickening after balloon denudation.

1987 • 45 citations

Interference of phorbolesters with endothelium-dependent vascular smooth muscle relaxation

1986 • 45 citations

Absence of effect of calcium antagonists on endothelium‐dependent relaxation in rabbit aorta

1987 • 44 citations

Methylene blue and ETYA block flow-dependent dilation in canine femoral artery

1986 • 43 citations

The Effect of the Phospholipase Inhibitor Mepacrine on Platelet Aggregation, the Platelet Release Reaction and Fibrinogen Binding to the Platelet Surface

1981 • 43 citations

Endothelium-derived relaxant factor inhibits effects of nitrocompounds in isolated arteries

1987 • 43 citations

The endothelium‐dependent relaxation of rabbit aorta: effects of antioxidants and hydroxylated eicosatetraenoic acids

1984 • 40 citations

The peripheral circulation

1985 • 39 citations

Aortic endothelial junctions in developing hypertension.

1985 • 38 citations

Determination of the muscarinic receptor subtype mediating vasodilatation.

1985 • 38 citations

An investigation of sodium‐calcium exchange in the smooth muscle of guinea‐pig ureter.

1987 • 38 citations

Effects of hypertension and hypercholesterolemia on vasodilatation in the rabbit.

1986 • 38 citations

Endothelium-derived relaxing factor is a selective relaxant of vascular smooth muscle.

1987 • 37 citations

Effect of histamine on aorta preparations of different species.

1984 • 36 citations

Blood flow- and endothelium-mediated vasomotion of iliac arteries in conscious dogs.

1987 • 36 citations

Properties and Mechanisms of Production and Action of Endothelium-Derived Relaxing Factor

1986 • 35 citations

Stabilization and partial characterization of endothelium-derived relaxing factor from cultured bovine aortic endothelial cells

1986 • 34 citations

Dilator and constrictor effects of acetylcholine on isolated rabbit aortic chains.

1962 • 32 citations

Reversible microcarrier-mediated junctional communication between endothelial and smooth muscle cell monolayers: an in vitro model of vascular cell interactions.

1985 • 32 citations

Endothelial cell loss enhances the pressor response in resistance vessels.

1984 • 30 citations

The affinity of some selective muscarinic receptor antagonists for the muscarinic receptor mediating endothelial-dependent relaxation of the rabbit and rat thoracic aorta

1986 • 30 citations

Modulation of Ion Channels by Phosphorylation and Second Messengers

1987 • 30 citations

Vasoactive effects of serotonin on proximal coronary arteries in awake dogs.

1987 • 28 citations

Amiloride analogues cause endothelium‐dependent relaxation in the canine coronary artery in vitro: possible role of Na⁺/Ca²⁺ exchange

1988 • 27 citations

Endothelium, arachidonic acid, and coronary vascular tone.

1987 • 27 citations

Histamine-induced relaxation of rat aorta. Importance of H1 receptor and vascular endothelium.

1984 • 27 citations

Autoradiographic localization of receptors in the cardiovascular system

1987 • 27 citations

Effect of a sustained release formulation of diltiazem on the development of atherosclerosis in cholesterol-fed rabbits

1987 • 25 citations

Interaction of a fluorescent probe with acetylcholine-activated synaptic membrane

1977 • 25 citations

Acetylcholine-induced relaxation in isolated dog cerebral arteries.

1979 • 25 citations

Vascular endothelium and the relaxation effect of histamine on aorta of the rat.

1982 • 24 citations

Abluminal release and asymmetrical response of the rabbit arterial wall to endothelium-derived relaxing factor.

1987 • 24 citations

The half‐life of endothelium‐derived relaxing factor released from bovine aortic endothelial cells in culture.

1987 • 23 citations

Development of a Large Fibromuscular Intimal Thickening Does Not Impair Endothelium-Dependent Relaxation in the Rabbit Carotid Artery

1987 • 22 citations

Abluminal Release and Asymmetrical Response of the Rabbit Arterial Wall to Endothelium-Derived Relaxing Factor

1987 • 22 citations

Release of endothelium-derived relaxing factor from freshly harvested porcine endothelial cells.

1987 • 22 citations

Vasoactive Effects of Serotonin on Proximal Coronary Arteries in Awake Dogs

1987 • 22 citations

Relaxing effects of 15-lipoxygenase products of arachidonic acid on rat aorta.

1987 • 20 citations

Endothelium derived relaxant factor.

1985 • 19 citations

Release of endothelium-derived relaxing factor from freshly harvested porcine endothelial cells.

1987 • 17 citations

Decreased Relaxation of Isolated Mesenteric Resistance Vessels from 2-Kidney, 1 Clip Goldblatt Hypertensive Rats

1983 • 15 citations

Effect of endothelium and carbachol on ?-adrenoceptor agonist stimulated uptake and efflux of 45Ca in rat isolated aorta

1987 • 15 citations

Role of endothelium in vascular responses to norepinephrine, serotonin and acetylcholine.

1984 • 15 citations

A comparison of the action of the endothelium‐derived relaxant factor and the inhibitory factor from the bovine retractor penis on rabbit aortic smooth muscle

1986 • 15 citations

Muscarinic receptors in isolated gastric fundic mucosal cells binding-activity relationships

1985 • 14 citations

Irreversible binding of quinacrine to nucleic acids during horseradish peroxidase-and prostaglandin synthetase-catalyzed oxidation

1983 • 14 citations

The Sense-Organs on the Legs of Our White Ants, Termes flavipes , Koll.

1893 • 12 citations

Stimulation of soluble coronary arterial guanylate cyclase by SIN-1

1986 • 11 citations

Azidoacridines as photoaffinity probes for ionic channels in excitable membranes

1982 • 11 citations

Simultaneous measurement of force and calcium uptake during acetylcholine-induced endothelium-dependent relaxation of rabbit thoracic aorta.

1987 • 10 citations

Role of calcium ion in maintenance of vascular smooth muscle tone

1987 • 9 citations

Vasodilatation and the discovery of endothelium‐derived relaxing factor

1987 • 9 citations

Selective Supersensitivity to Norepinephrine in Intimal Thickened Rabbit Aorta

1985 • 9 citations

Inhibitory effect of quinacrine on myocardial reactive hyperemia in the dog.

1985 • 9 citations

Endothelium-Dependent Responses in Large Arteries and in the Microcirculation

1988 • 9 citations

An analysis of the inhibitory effects of quinine and mepacrine in the guinea-pig isolated ileum

1980 • 8 citations

ENDOTHELIUM‐DEPENDENT RELAXATION IS UNALTERED BY HYPERTENSION, CHOLESTEROL OR INTIMAL THICKENING

1986 • 6 citations

EDRF: a Ca2+ -dependent chemical moiety(ies)

1985 • 6 citations

Endothelial Cell Metabolism

2015 • 6 citations

Mepacrine-induced inhibition of human platelet cyclic-GMP phosphodiesterase

1984 • 5 citations

ENDOTHELIAL ALPHA-ADRENOCEPTORS

1988 • 5 citations

Deleted Work

1955 • 0 citations