Role of endothelium in responses of vascular smooth muscle.

Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates.

1981 • 1,624 citations

Drugs which inhibit prostaglandin biosynthesis.

1974 • 1,325 citations

Agonist-induced endothelium-dependent relaxation in rat thoracic aorta may be mediated through cGMP.

1983 • 949 citations

Stimulation of Endothelial Cell Prostacyclin Production by Thrombin, Trypsin, and the Ionophore A 23187

1978 • 715 citations

Differential formation of prostacyclin (PGX or PGI2) by layers of the arterial wall. An explanation for the anti-thrombotic properties of vascular endothelium

1977 • 683 citations

The importance of phospholipase-A2 in prostaglandin biosynthesis

1976 • 647 citations

The effect of sympathetic nerve stimulation on vasoconstrictor responses in perfused mesenteric blood vessels of the rat

1965 • 630 citations

Synthesis of prostaglandin I2 (prostacyclin) by cultured human and bovine endothelial cells.

1977 • 625 citations

Heterogeneous behavior of the canine arterial and venous wall. Importance of the endothelium.

1982 • 545 citations

Relationship between cyclic guanosine 3':5'-monophosphate formation and relaxation of coronary arterial smooth muscle by glyceryl trinitrate, nitroprusside, nitrite and nitric oxide: effects of methylene blue and methemoglobin.

1981 • 527 citations

Role of endothelial cells in relaxation of isolated arteries by bradykinin.

1982 • 420 citations

Vascular endothelial and smooth muscle cells in culture selectively release adenine nucleotides

1979 • 402 citations

Prostacyclin is a circulating hormone

1978 • 380 citations

Role of the intima in cholinergic and purinergic relaxation of isolated canine femoral arteries.

1981 • 380 citations

Localisation and stimulation of prostacyclin production in vascular cells

1978 • 356 citations

Endothelium-dependent inhibitory effects of acetylcholine, adenosine triphosphate, thrombin and arachidonic acid in the canine femoral artery.

1982 • 345 citations

Coronary Vascular Reactivity After Acute Myocardial Ischemia

1982 • 336 citations

Evidence for cyclic GMP-mediated relaxant effects of nitro-compounds in coronary smooth muscle

1979 • 301 citations

Regulation of adenosine cyclic 3',5'-monophosphate and guanosine cyclic 3',5'-monophosphate levels and contractility in bovine tracheal smooth muscle.

1977 • 286 citations

Anoxia and endothelium‐dependent reactivity of the canine femoral artery.

1983 • 259 citations

Role of the endothelium in the vasodilator response of rat thoracic aorta to histamine

1983 • 249 citations

Effect of bradykinin and thrombin on prostacyclin synthesis in endothelial cells from calf and pig aorta and human umbilical cord vein

1980 • 249 citations

The requirement for endothelial cells in the relaxation of arteries by acetylcholine and some other vasodilators

1981 • 231 citations

Acetylcholine and Bradykinin Relax Intrapulmonary Arteries by Acting on Endothelial Cells: Role in Lung Vascular Diseases

1981 • 226 citations

Chemical modification of the histidine residue in phospholipase A2 (Naja naja naja). A case of half-site reactivity.

1977 • 210 citations

Mode of coupling between hormone receptors and adenylate cyclase elucidated by modulation of membrane fluidity

1978 • 202 citations

Calcium- and endothelial-mediated vascular smooth muscle relaxation in rabbit aorta.

1982 • 202 citations

Fatty acids as modulators of membrane functions: catecholamine-activated adenylate cyclase of the turkey erythrocyte.

1975 • 187 citations

Properties and regulation of guanylate cyclase and some proposed functions for cyclic GMP.

1979 • 187 citations

Endothelium‐dependent relaxation of the pig aorta: relationship to stimulation of ⁸⁶Rb efflux from isolated endothelial cells

1983 • 166 citations

Hormone interactions in the isolated rabbit heart. Synthesis and coronary vasomotor effects of prostaglandins, angiotensin, and bradykinin.

1975 • 160 citations

The Photoactivated Relaxation of Smooth Muscle of Rabbit Aorta

1961 • 160 citations

Effects of sodium nitroprusside and other smooth muscle relaxants on cyclic GMP formation in smooth muscle and platelets.

1978 • 156 citations

Blood vessel-hormone interactions: angiotensin, bradykinin, and prostaglandins

1977 • 134 citations

Stimulation of human platelet guanylate cyclase by unsaturated fatty acid peroxides.

1977 • 110 citations

Cholinergic mechanism in the large cat cerebral artery.

1982 • 98 citations

Endothelium-dependent relaxation of rabbit aorta. I. Relaxation stimulated by arachidonic acid.

1983 • 96 citations

Interaction between Na+,K+ exchanges and the direct inhibitory effect of acetylcholine on canine femoral arteries.

1980 • 96 citations

THE EFFECTS OF ACETYLCHOLINE ON THE MEMBRANE AND CONTRACTILE PROPERTIES OF SMOOTH MUSCLE CELLS OF THE RABBIT SUPERIOR MESENTERIC ARTERY

1978 • 95 citations

Endothelium-dependent relaxation of rabbit aorta. II. Inhibition of relaxation stimulated by methacholine and A23187 with antagonists of arachidonic acid metabolism.

1983 • 74 citations

Relaxation of hormonally stimulated smooth muscular tissues by the 8-bromo derivative of cyclic GMP

1979 • 73 citations

Actions of bradykinin on isolated cerebral and peripheral arteries

1977 • 69 citations

Endothelial mechanism in the vascular action of hydralazine.

1983 • 66 citations

BRADYKININ‐INDUCED RELAXATION OF RENAL AND PULMONARY ARTERIES IS DEPENDENT UPON INTACT ENDOTHELIAL CELLS

1981 • 66 citations

Cholinergic inhibition of adrenergic transmission.

1977 • 43 citations

Redox modulation of splenic cell soluble guanylate cyclase activity: activation by hydrophilic and hydrophobic oxidants represented by ascorbic and dehydroascorbic acids, fatty acid hydroperoxides, and prostaglandin endoperoxides.

1978 • 40 citations

Effect of the thromboxane synthetase inhibitor UK-37,248 (dazoxiben) upon platelet aggregation, coronary artery thrombosis and vascular reactivity.

1983 • 33 citations

Vasoconstriction of the isolated rabbit ear artery caused by nicotinic agonists acting on adrenergic neurons.

1975 • 27 citations

Asymmetry of consequences of drug disposition mechanisms in the wall of the rabbit aorta.

1980 • 21 citations

Stability of Catecholamines Immobilized on Glass Beads

1974 • 12 citations

Endothelium and relaxation of isolated canine arteries

1980 • 10 citations

Oxygen-dependency of the acetylcholine induced relaxation in vascular smooth muscle.

1978 • 10 citations

REDUCTION OF LEUKOCYTE MIGRATION BY A CYCLO-OXYGENASE AND LIPOXYGENASE INHIBITOR

1978 • 9 citations

Prostaglandin I2 Synthesis and Vascular Effects in Isolated Coronary Artery1

2015 • 2 citations

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