Hematopoietic cellular therapy: implications for the flow cytometry laboratory

Phenotypic Analysis of Antigen-Specific T Lymphocytes

1996 • 3,611 citations

Graft-versus-leukemia reactions after bone marrow transplantation

1990 • 2,781 citations

Counting Antigen-Specific CD8 T Cells: A Reevaluation of Bystander Activation during Viral Infection

1998 • 1,996 citations

The ISHAGE Guidelines for CD34+ Cell Determination by Flow Cytometry

1996 • 1,249 citations

Treatment of High-Risk Acute Leukemia with T-Cell–Depleted Stem Cells from Related Donors with One Fully Mismatched HLA Haplotype

1998 • 1,200 citations

Antigenic analysis of hematopoiesis. III. A hematopoietic progenitor cell surface antigen defined by a monoclonal antibody raised against KG-1a cells.

1984 • 1,193 citations

Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients

1999 • 1,131 citations

Age, Thymopoiesis, and CD4+ T-Lymphocyte Regeneration after Intensive Chemotherapy

1995 • 1,066 citations

Bone Marrow Transplantation for Chronic Myelogenous Leukemia in Chronic Phase

1988 • 887 citations

Marrow Transplantation from Related Donors Other Than HLA-Identical Siblings

1985 • 844 citations

Effect of HLA Compatibility on Engraftment of Bone Marrow Transplants in Patients with Leukemia or Lymphoma

1989 • 693 citations

Engraftment after infusion of CD34+ marrow cells in patients with breast cancer or neuroblastoma

1991 • 538 citations

Flow cytometry for clinical estimation of circulating hematopoietic progenitors for autologous transplantation in cancer patients

1991 • 519 citations

Effects of in vitro depletion of T cells in HLA-identical allogeneic marrow grafts

1985 • 517 citations

Ox-40 Ligand: A Potent Costimulatory Molecule for Sustaining Primary CD4 T Cell Responses

1998 • 515 citations

Comparison of Immune Reconstitution After Unrelated and Related T-Cell–Depleted Bone Marrow Transplantation: Effect of Patient Age and Donor Leukocyte Infusions

1999 • 486 citations

High Frequency of Skin-homing Melanocyte-specific Cytotoxic T Lymphocytes in Autoimmune Vitiligo

1998 • 446 citations

The kinetics of immune reconstitution after human marrow transplantation

1987 • 428 citations

Distinctions Between CD8+ and CD4+ T-Cell Regenerative Pathways Result in Prolonged T-Cell Subset Imbalance After Intensive Chemotherapy

1997 • 388 citations

Glucocorticoid-mediated repression of nuclear factor-κBdependent transcription involves direct interference with transactivation

1997 • 371 citations

Effect of HLA incompatibility on graft-versus-host disease, relapse, and survival after marrow transplantation for patients with leukemia or lymphoma

1990 • 346 citations

Identification of a human OX-40 ligand, a costimulator of CD4+ T cells with homology to tumor necrosis factor.

1994 • 271 citations

Recovery of antibody production in human allogeneic marrow graft recipients: influence of time posttransplantation, the presence or absence of chronic graft-versus-host disease, and antithymocyte globulin treatment

1981 • 269 citations

Immune reconstitution following bone marrow transplantation: comparison of recipients of T-cell depleted marrow with recipients of conventional marrow grafts

1989 • 261 citations

T-cell regeneration: all repertoires are not created equal

1997 • 246 citations

GRAFT REJECTION IN RECIPIENTS OF T-CELL-DEPLETED HLA-NONIDENTICAL MARROW TRANSPLANTS FOR LEUKEMIA

1987 • 241 citations

Use of Partially Mismatched Related Donors Extends Access to Allogeneic Marrow Transplant

1997 • 220 citations

GRAFT REJECTION IN RECIPIENTS OF T-CELL-DEPLETED HLA-NONIDENTICAL MARROW TRANSPLANTS FOR LEUKEMIA

1987 • 220 citations

Allogeneic cell therapy for relapsed leukemia after bone marrow transplantation with donor peripheral blood lymphocytes.

1995 • 215 citations

Reconstruction of the haemopoietic and immune systems after marrow transplantation.

1990 • 210 citations

Rapid flow cytometric method for measuring lymphocyte subset activation

1995 • 202 citations

Graft-versus-leukemia: no longer an epiphenomenon [editorial]

1993 • 197 citations

Bone marrow transplantation from related donors other than HLA-identical siblings: effect of T cell depletion.

1991 • 196 citations

Graft failure in patients receiving T cell-depleted HLA-identical allogeneic marrow transplants.

1988 • 195 citations

Gamma/delta T cell clones and natural killer cell clones mediate distinct patterns of non-major histocompatibility complex-restricted cytolysis.

1990 • 176 citations

Graft failure after T-cell-depleted human leukocyte antigen identical marrow transplants for leukemia: I. Analysis of risk factors and results of secondary transplants

1989 • 167 citations

Selective depletion of myelin–reactive T cells with the anti–OX–40 antibody ameliorates autoimmune encephalomyelitis

1996 • 159 citations

The effect of thymic function on immunocompetence following bone marrow transplantation.

1995 • 155 citations

Reconstruction of the immune system after unrelated or partially matched T-cell-depleted bone marrow transplantation in children: immunophenotypic analysis and factors affecting the speed of recovery

1996 • 148 citations

B-cell differentiation following autologous, conventional, or T-cell depleted bone marrow transplantation: a recapitulation of normal B-cell ontogeny

1990 • 145 citations

Isolation and expansion of cytomegalovirus-specific cytotoxic T lymphocytes to clinical scale from a single blood draw using dendritic cells and HLA-tetramers

2001 • 141 citations

Human peripheral gamma delta T cells recognize hsp60 molecules on Daudi Burkitt's lymphoma cells.

1993 • 135 citations

T-lymphocyte reconstitution in recipients of bone marrow transplants with and without GVHD: imbalances of T-cell subpopulations having unique regulatory and cognitive functions

1982 • 125 citations

Interleukin 2 prevents graft-versus-host disease while preserving the graft-versus-leukemia effect of allogeneic T cells.

1990 • 122 citations

Long lasting IgG subclass and antibacterial polysaccharide antibody deficiency after allogeneic bone marrow transplantation

1987 • 115 citations

Measurement of T-cell CD69 expression: A rapid and efficient means to assess mitogen- or antigen-induced proliferative capacity in normals

1996 • 110 citations

Reconstitution of B cell immunity following bone marrow transplantation.

1992 • 109 citations

Immune reconstitution following allogeneic peripheral blood progenitor cell transplantation

1999 • 106 citations

Prolonged CD4 depletion after sequential autologous peripheral blood progenitor cell infusions in children and young adults

2000 • 102 citations

Cutting Edge: Rapid Cloning of Tumor-Specific CTL Suitable for Adoptive Immunotherapy of Melanoma

1999 • 94 citations

Infection Complicating Bone Marrow Transplantation

1994 • 89 citations

Critical Role for CD8 in Binding of MHC Tetramers to TCR: CD8 Antibodies Block Specific Binding of Human Tumor- Specific MHC-Peptide Tetramers to TCR

2001 • 86 citations

Expression of the T-Cell Activation Antigen, OX-40, Identifies Alloreactive T Cells in Acute Graft-Versus-Host Disease

1997 • 83 citations

Reconstitution of T-cell function after CD6-depleted allogeneic bone marrow transplantation

1990 • 79 citations

Determination of natural killer cell function by flow cytometry

1996 • 75 citations

Direct Detection and Magnetic Isolation ofChlamydia trachomatisMajor Outer Membrane Protein-Specific CD8+ CTLs with HLA Class I Tetramers

2000 • 73 citations

Principles of graft-vs.-leukemia reactivity.

1995 • 70 citations

Phenotypic and functional reconstitution of peripheral blood lymphocytes following T cell-depleted bone marrow transplantation from partially mismatched related donors

1998 • 70 citations

Use of unrelated marrow grafts compensates for reduced graft-versus- leukemia reactivity after T-cell-depleted allogeneic marrow transplantation for chronic myelogenous leukemia

1995 • 69 citations

Reconstitution of T-cell function after CD6-depleted allogeneic bone marrow transplantation

1990 • 62 citations

COMBINED IN VITRO AND IN VIVO T LYMPHOCYTE DEPLETION FOR THE CONTROL OF GRAFT-VERSUS-HOST DISEASE FOLLOWING HAPLOIDENTICAL MARROW TRANSPLANT

1996 • 62 citations

The Influence of Flow Cytometric Gating Strategy on the Standardization of CD34+ Cell Quantitation: An Australian Multicenter Study

1996 • 57 citations

Non‐MHC‐restricted cytotoxic cells: their roles in the control and treatment of leukaemias

2001 • 57 citations

Recombinant human single-chain MHC-peptide complexes made fromE. coli byin vitro refolding: functional single-chain MHC-peptide complexes and tetramers with tumor associated antigens

2000 • 54 citations

The role of donor lymphoid cells in allogeneic marrow engraftment.

1990 • 51 citations

COMPARISON OF CAMPATH-1 PLUS COMPLEMENT, ANTI-T CELL RICIN A CHAIN IMMUNOTOXIN, AND SOYBEAN AGGLUTININ ALONE OR IN COMBINATION WITH SHEEP ERYTHROCYTES OR IMMUNOMAGNETIC BEADS

1989 • 50 citations

Cutting Edge: Characterization of Allorestricted and Peptide-Selective Alloreactive T Cells Using HLA-Tetramer Selection

2001 • 50 citations

Factors predicting engraftment of autologous blood stem cells: CD34+ subsets inferior to the total CD34+ cell dose

1999 • 47 citations

EVIDENCE FOR THE INVOLVEMENT OF HOST-DERIVED OKT8-POSITIVE T CELLS IN THE REJECTION OF T-DEPLETED, HLA-IDENTICAL BONE MARROW GRAFTS

1987 • 47 citations

Frequency of bone marrow T cells responding to HLA-identical non-leukemic and leukemic stimulator cells.

1993 • 45 citations

In Vitro Generation of Allospecific Human CD8+ T Cells of Tc1 and Tc2 Phenotype

1997 • 45 citations

γδ T Cell Receptor Analysis Supports a Role for HSP 70 Selection of Lymphocytes in Multiple Sclerosis Lesions

1995 • 41 citations

A Whole-Blood Assay for Qualitative and Semiquantitative Measurements of CD69 Surface Expression on CD4 and CD8 T Lymphocytes Using Flow Cytometry

1998 • 40 citations

Characterization of cells emerging at the time of graft failure after bone marrow transplantation from an unrelated marrow donor

1993 • 40 citations

T cell depletion of HLA and haploidentical marrow reduces graft-versus-host disease but it may impair a graft-versus-leukemia effect.

1987 • 38 citations

Measurement of CD34⁺Cells in Bone Marrow by Flow Cytometry

1993 • 33 citations

Potential antileukemic effect of gamma delta T cells in acute lymphoblastic leukemia.

1995 • 33 citations

Abundance of a restricted fetal B cell repertoire in marrow transplant recipients.

1994 • 33 citations

Allo-Major Histocompatibility Complex–Restricted Cytotoxic T Lymphocytes Engraft in Bone Marrow Transplant Recipients Without Causing Graft-Versus-Host Disease

1999 • 32 citations

Expression of CD134 (0X-40) on T cells during the first 100 days following allogeneic bone marrow transplantation as a marker for lymphocyte activation and therapy-resistant graft-versus-host disease

1999 • 29 citations

CD34+ cell enumeration in peripheral blood and apheresis samples, using two laboratory diagnostic kits or an institutional protocol

1999 • 25 citations

Graft failure after bone marrow transplantation from unrelated donors using busulphan and cyclophosphamide for conditioning.

1994 • 25 citations

Clinical Utility in Maximizing CD34 ⁺ Cell Count in Stem Cell Grafts

1999 • 24 citations

A flow cytometric long-term cytotoxicity assay

1994 • 22 citations

Graft-versus-Host Disease in Bone Marrow Transplantation: Experimental, Laboratory, and Clinical Contributions of the Last Few Years

1993 • 21 citations

Acute rejection of marrow grafts in patients transplanted from a partially mismatched related donor: clinical and immunologic characteristics.

1996 • 17 citations

Characterization of acute bone marrow graft rejection in T cell-depleted, partially mismatched related donor bone marrow transplantation.

1995 • 14 citations

Donor leukocyte infusion for treatment of graft rejection post partially mismatched related donor bone marrow transplant

1998 • 13 citations

Quantification of CD34+ cells mobilized into the peripheral blood predicts the yield of the leukapheresis product and can replace progenitor assays.

1997 • 8 citations

Immunoreconstitution after human bone marrow transplantation.

1989 • 2 citations

Strategies to Enhance the Graft-versus-Malignancy Effect in Allogeneic Transplants

1995 • 2 citations

Immunophenotyping of peripheral blood lymphocytes in the diagnosis of acute graft-versus-host disease.

1989 • 2 citations