Strategies to Enhance the Graft-versus-Malignancy Effect in Allogeneic Transplants

Graft-versus-leukemia reactions after bone marrow transplantation

1990 • 2,781 citations

Fas and Perforin Pathways as Major Mechanisms of T Cell-Mediated Cytotoxicity

1994 • 1,558 citations

Donor leukocyte transfusions for treatment of recurrent chronic myelogenous leukemia in marrow transplant patients

1990 • 1,544 citations

Bone Marrow Transplantation for Chronic Myelogenous Leukemia in Chronic Phase

1988 • 887 citations

Identification of a Peptide Recognized by Five Melanoma-Specific Human Cytotoxic T Cell Lines

1994 • 841 citations

Peptides Naturally Presented by MHC Class I Molecules

1993 • 803 citations

T-cell depletion of HLA-identical transplants in leukemia

1991 • 771 citations

Influence of acute and chronic graft-versus-host disease on relapse and survival after bone marrow transplantation from HLA-identical siblings as treatment of acute and chronic leukemia [published erratum appears in Blood 1989 Aug 15;74(3):1180]

1989 • 623 citations

Cytokine dysregulation and acute graft-versus-host disease

1992 • 617 citations

Cytokine dysregulation and acute graft-versus-host disease

1992 • 565 citations

Influence of acute and chronic graft-versus-host disease on relapse and survival after bone marrow transplantation from HLA-identical siblings as treatment of acute and chronic leukemia [published erratum appears in Blood 1989 Aug 15;74(3):1180]

1989 • 448 citations

Relapse of chronic myeloid leukemia after allogeneic bone marrow transplant: the case for giving donor leukocyte transfusions before the onset of hematologic relapse

1994 • 358 citations

Salvage immunotherapy using donor leukocyte infusions as treatment for relapsed chronic myelogenous leukemia after allogeneic bone marrow transplantation: efficacy and toxicity of a defined T-cell dose

1993 • 356 citations

Effect of HLA incompatibility on graft-versus-host disease, relapse, and survival after marrow transplantation for patients with leukemia or lymphoma

1990 • 346 citations

Tissue distribution of human minor histocompatibility antigens. Ubiquitous versus restricted tissue distribution indicates heterogeneity among human cytotoxic T lymphocyte-defined non-MHC antigens.

1992 • 320 citations

Identical-Twin Bone Marrow Transplants for Leukemia

1994 • 291 citations

T CELL SUBSETS AND GRAFT-VERSUS-HOST DISEASE

1987 • 223 citations

Induction of NK cell activity against fresh human leukemia in culture with interleukin 2.

1987 • 215 citations

Selective depletion of CD8+ T lymphocytes for prevention of graft- versus-host disease after allogeneic bone marrow transplantation

1990 • 180 citations

Cytotoxic T lymphocytes against a soluble protein

1987 • 178 citations

Selective depletion of CD8+ T lymphocytes for prevention of graft- versus-host disease after allogeneic bone marrow transplantation

1990 • 166 citations

Prediction of graft versus host disease by frequency analysis of cytotoxic T cells after unrelated donor bone marrow transplantation.

1989 • 165 citations

Minor histocompatibility antigens

1990 • 153 citations

Haematopoietic Chimera in Man After Allogenic (Homologous) Bone-marrow Transplantation

1963 • 152 citations

Anti-leukemia potential of interleukin-2 activated natural killer cells after bone marrow transplantation for chronic myelogenous leukemia

1990 • 150 citations

Delayed infusion of normal donor cells after MHC-matched bone marrow transplantation provides an antileukemia reaction without graft-versus-host disease.

1993 • 147 citations

The graft-versus-leukemia (GVL) phenomenon: is GVL separable from GVHD?

1990 • 117 citations

Minor histocompatibility antigens

1990 • 95 citations

Minor histocompatibility antigens in man and their role in transplantation

1988 • 91 citations

In vitro separation of host specific graft-versus-host and graft-versus-leukemia cytotoxic T cell activities.

1992 • 86 citations

Attenuation of graft-versus-host disease and graft rejection by ex vivo immunotoxin elimination of alloreactive T cells in an H-2 haplotype disparate mouse combination

1994 • 85 citations

T cell and NK cell mediated graft-versus-leukaemia reactivity following donor buffy coat transfusion to treat relapse after marrow transplantation for chronic myeloid leukaemia.

1993 • 81 citations

Kettering award lecture. The role of marrow transplantation in the eradication of malignant disease

1982 • 71 citations

Distinct T cell populations distinguish chronic myeloid leukaemia cells from lymphocytes in the same individual: a model for separating GVHD from GVL reactions.

1994 • 63 citations

Generation of Donor-Derived Antileukemic Cytotoxic T-Lymphocyte Responses for Treatment of Relapsed Leukemia After Allogeneic HLA-Identical Bone Marrow Transplantation

1993 • 57 citations

Bone Marrow Transplantation in Practice

1992 • 52 citations

Minimal residual disease after bone marrow transplantation for chronic myelogenous leukemia and implications for graft-versus-leukemia effect: a review of recent results.

1994 • 43 citations

Binding of BCR/ABL junctional peptides to major histocompatibility complex (MHC) class I molecules: studies in antigen-processing defective cell lines.

1994 • 42 citations

Determinants of engraftment after allogeneic marrow transplantation [editorial]

1992 • 38 citations

Minor histocompatibility antigens HA-1-, -2-, and -4-, and HY-specific cytotoxic T-cell clones inhibit human hematopoietic progenitor cell growth by a mechanism that is dependent on direct cell-cell contact

1993 • 36 citations

Cellular and cytokine-mediated effects of CD4-positive lymphocyte lines generated in vitro against chronic myelogenous leukemia.

1995 • 34 citations

Immune responses to chronic myeloid leukaemia.

1992 • 31 citations

Processing of Self-Proteins and Its Impact on Shaping the T Cell Repertoire, Autoimmunity and Immune Regulation

1993 • 23 citations

Evidence for an involvement of T4+ cytotoxic T cells in tumor immunity

1989 • 9 citations