Increased secretion of TGF‐β1 by peripheral blood mononuclear cells from patients with Type 1 diabetes mellitus with diabetic nephropathy

Angiotensin II stimulates extracellular matrix protein synthesis through induction of transforming growth factor-beta expression in rat glomerular mesangial cells.

1994 • 1,063 citations

Expression of transforming growth factor beta is elevated in human and experimental diabetic nephropathy.

1993 • 819 citations

The changing natural history of nephropathy in type I Diabetes

1985 • 792 citations

Genetic control of the circulating concentration of transforming growth factor type beta1

1999 • 749 citations

Stimulation of collagen gene expression and protein synthesis in murine mesangial cells by high glucose is mediated by autocrine activation of transforming growth factor-beta.

1994 • 593 citations

Hyperglycemia and Diabetic Kidney Disease: The Case for Transforming Growth Factor–β as a Key Mediator

1995 • 560 citations

Polymorphisms of the Transforming Growth Factor-β1 Gene in Relation to Myocardial Infarction and Blood Pressure

1996 • 370 citations

Advanced glycation end products up-regulate gene expression found in diabetic glomerular disease.

1994 • 298 citations

Increased Renal Production of Transforming Growth Factor-β1 in Patients with Type II Diabetes

1997 • 275 citations

Elevated glucose stimulates TGF-β gene expression and bioactivity in proximal tubule

1992 • 264 citations

Production of extracellular matrix by glomerular epithelial cells is regulated by transforming growth factor-β1

1992 • 248 citations

Expression of transforming growth factor-beta1 and type IV collagen in the renal tubulointerstitium in experimental diabetes: effects of ACE inhibition.

1998 • 203 citations

The autocrine production of transforming growth factor-beta 1 during lymphocyte activation. A study with a monoclonal antibody-based ELISA.

1990 • 169 citations

Transcriptional activation of transforming growth factor-β1 in mesangial cell culture by high glucose concentration

1998 • 167 citations

Predictive value of microalbuminuria in patients with insulin-dependent diabetes of long duration.

1992 • 162 citations

TGF-β ₁ DNA Polymorphisms, Protein Levels, and Blood Pressure

1999 • 151 citations

Urinary transforming growth factor- 1 in membranous glomerulonephritis

1997 • 88 citations

Predisposition to essential hypertension and development of diabetic nephropathy in IDDM patients.

1998 • 81 citations

Regulation of Glomerular Epithelial Cell Production of Fibronectin and Transforming Growth Factor-β by High Glucose, Not by Angiotensin II

1997 • 59 citations

TGF-beta1 gene mutations in insulin-dependent diabetes mellitus and diabetic nephropathy.

1998 • 46 citations

Characterization of cytokine gene expression in CD4+ and CD8+ T cells after activation with phorbol myristate acetate and phytohaemagglutinin

1992 • 41 citations

Angiotensin converting enzyme inhibition reduces the expression of transforming growth factor-β1 and type IV collagen in diabetic vasculopathy

1998 • 30 citations

Regulation of glomerular epithelial cell production of fibronectin and transforming growth factor-beta by high glucose, not by angiotensin II

1997 • 11 citations

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