Angiotensin converting enzyme inhibition reduces the expression of transforming growth factor-β1 and type IV collagen in diabetic vasculopathy

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

The Effect of Angiotensin-Converting-Enzyme Inhibition on Diabetic Nephropathy

1993 • 5,296 citations

Transforming Growth Factor β in Tissue Fibrosis

1994 • 3,055 citations

Renin-angiotensin system: biochemistry and mechanisms of action.

1977 • 1,373 citations

Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells.

1988 • 1,077 citations

Angiotensin II stimulates extracellular matrix protein synthesis through induction of transforming growth factor-beta expression in rat glomerular mesangial cells.

1994 • 1,063 citations

Inhibitors of Angiotensin-Converting Enzyme Prevent Myointimal Proliferation After Vascular Injury

1989 • 1,061 citations

Expression of transforming growth factor beta is elevated in human and experimental diabetic nephropathy.

1993 • 819 citations

Angiotensin II induces smooth muscle cell proliferation in the normal and injured rat arterial wall.

1991 • 751 citations

Vascular smooth muscle cell hypertrophy vs. hyperplasia. Autocrine transforming growth factor-beta 1 expression determines growth response to angiotensin II.

1992 • 648 citations

Stimulation of collagen gene expression and protein synthesis in murine mesangial cells by high glucose is mediated by autocrine activation of transforming growth factor-beta.

1994 • 593 citations

Hyperglycemia and Diabetic Kidney Disease: The Case for Transforming Growth Factor–β as a Key Mediator

1995 • 560 citations

Die enzymatische Bestimmung von Glucose und Fructose nebeneinander

1961 • 506 citations

Validation in awake rats of a tail-cuff method for measuring systolic pressure.

1973 • 492 citations

Prevention and Treatment of the Complications of Diabetes Mellitus

1995 • 366 citations

Transforming growth factor-beta-induced growth inhibition and cellular hypertrophy in cultured vascular smooth muscle cells.

1988 • 305 citations

Advanced glycation end products up-regulate gene expression found in diabetic glomerular disease.

1994 • 298 citations

Angiotensin II stimulates collagen synthesis in cultured vascular smooth muscle cells

1991 • 288 citations

Role of kinins and nitric oxide in the effects of angiotensin converting enzyme inhibitors on neointima formation.

1993 • 233 citations

Evidence for direct local effect of angiotensin in vascular hypertrophy. In vivo gene transfer of angiotensin converting enzyme.

1994 • 213 citations

Conversion of angiotensin I to angiotensin II

1976 • 211 citations

Expression of transforming growth factor-beta1 and type IV collagen in the renal tubulointerstitium in experimental diabetes: effects of ACE inhibition.

1998 • 203 citations

Vascular hypertrophy in experimental diabetes. Role of advanced glycation end products.

1997 • 191 citations

Glomerular cells, extracellular matrix accumulation, and the development of glomerulosclerosis in the remnant kidney model.

1992 • 190 citations

Blood pressure-independent effect of angiotensin inhibition on vascular lesions of chronic renal failure

1992 • 166 citations

Bradykinin inhibition of EGF- and PDGF-induced DNA synthesis in human fibroblasts

1993 • 139 citations

Hyperglycemia and diabetic kidney disease. The case for transforming growth factor-beta as a key mediator

1995 • 136 citations

Role of Angiotensin II and Bradykinin in Experimental Diabetic Nephropathy: Functional and Structural Studies

1997 • 123 citations

Basement membrane abnormalities in diabetes mellitus: Relationship to clinical microangiopathy

1988 • 114 citations

Diabetes-Associated Mesenteric Vascular Hypertrophy Is Attenuated by Angiotensin-Converting Enzyme Inhibition

1994 • 77 citations

Central Role of TGF-β in the Pathogenesis of Diabetic Nephropathy and Macrovascular Complications: A Hypothesis

1996 • 65 citations

Role of angiotensin II and bradykinin in experimental diabetic nephropathy. Functional and structural studies

1997 • 48 citations

The kidney disease of diabetes mellitus (KDDM): A cell and molecular biology approach

1993 • 44 citations

Comparison of effects of ACE inhibition with calcium channel blockade on renal disease in a model combining genetic hypertension and diabetes

1995 • 33 citations

Diabetes-associated mesenteric vascular hypertrophy is attenuated by angiotensin-converting enzyme inhibition

1994 • 30 citations

Kinins or nitric oxide, or both, are involved in the antitrophic effects of angiotensin converting enzyme inhibitors on diabetes-associated mesenteric vascular hypertrophy in the rat

1996 • 30 citations

Angiotensin-Converting Enzyme Inhibition Reduces Diabetes-Induced Vascular Hypertrophy: Morphometric Studies

1995 • 24 citations