Hyperthermia in the Neurosurgical Intensive Care Unit

Small Differences in Intraischemic Brain Temperature Critically Determine the Extent of Ischemic Neuronal Injury

1987 • 1,821 citations

Treatment of Traumatic Brain Injury with Moderate Hypothermia

1997 • 1,308 citations

Body temperature in acute stroke: relation to stroke severity, infarct size, mortality, and outcome

1996 • 898 citations

Effect of mild hypothermia on uncontrollable intracranial hypertension after severe head injury

1993 • 579 citations

A Phase II Study of Moderate Hypothermia in Severe Brain Injury

1993 • 546 citations

The use of moderate therapeutic hypothermia for patients with severe head injuries: a preliminary report

1993 • 534 citations

Combating Hyperthermia in Acute Stroke

1998 • 489 citations

Fever in Acute Stroke Worsens Prognosis

1995 • 442 citations

The effect of mild hyperthermia and hypothermia on brain damage following 5, 10, and 15 minutes of forebrain ischemia

1990 • 409 citations

Detection of Free Radical Activity During Transient Global Ischemia and Recirculation: Effects of Intraischemic Brain Temperature Modulation

1995 • 388 citations

The Importance of Brain Temperature in Alterations of the Blood-Brain Barrier Following Cerebral Ischemia

1990 • 373 citations

Timing for Fever-Related Brain Damage in Acute Ischemic Stroke

1998 • 372 citations

The Significance of Brain Temperature in Focal Cerebral Ischemia: Histopathological Consequences of Middle Cerebral Artery Occlusion in the Rat

1992 • 353 citations

Effects of normothermic versus mild hyperthermic forebrain ischemia in rats.

1990 • 327 citations

Brain Temperature Alters Hydroxyl Radical Production during Cerebral Ischemia/Reperfusion in Rats

1996 • 293 citations

Temperature Changes of greater or equal to 1 degree Celsius Alter Functional Neurologic Outcome and Histopathology in a Canine Model of Complete Cerebral Ischemia

1995 • 248 citations

Delayed Postischemic Hyperthermia in Awake Rats Worsens the Histopathological Outcome of Transient Focal Cerebral Ischemia

1996 • 233 citations

Delayed Posttraumatic Brain Hyperthermia Worsens Outcome after Fluid Percussion Brain Injury: A Light and Electron Microscopic Study in Rats

1996 • 216 citations

Long-lasting Neuroprotective Effect of Postischemic Hypothermia and Treatment With an Anti-inflammatory/Antipyretic Drug

1996 • 215 citations

Prevention of Postischemic Hyperthermia Prevents Ischemic Injury of CA₁ Neurons in Gerbils

1990 • 186 citations

Hyperthermia delayed by 24 hours aggravates neuronal damage in rat hippocampus following global ischemia

1997 • 184 citations

Excitotoxic index — a biochemical marker of selective vulnerability

1991 • 178 citations

Temperature modulation of ischemic neuronal death and inhibition of calcium/calmodulin-dependent protein kinase II in gerbils.

1990 • 150 citations

Occurrence of Potentially Detrimental Temperature Alterations in Hospitalized Patients at Risk for Brain Injury

1998 • 147 citations

Interrelationships between increased vascular permeability and acute neuronal damage following temperature-controlled brain ischemia in rats

1991 • 142 citations

THE PROGNOSTIC SIGNIFICANCE of SUBFEBRILITY and FEVER IN ISCHAEMIC CEREBRAL INFARCTION

1976 • 134 citations

Mortality and Morbidity of Acute Cerebral Infarction Related to Temperature and Basal Analytic Parameters

1994 • 123 citations

Diminished neuronal damage in the rat brain by late treatment with the antipyretic drug dipyrone or cooling following cerebral ischemia

1996 • 113 citations

Aggravation of Acute Ischemic Stroke by Hyperthermia Is Related to an Excitotoxic Mechanism

1999 • 111 citations

Effect of hyperthermia on glutamate release in ischemic penumbra after middle cerebral artery occlusion in rats

1994 • 104 citations

Regional Alterations of Protein Kinase C Activity Following Transient Cerebral Ischemia: Effects of Intraischemic Brain Temperature Modulation

1994 • 102 citations

Hyperthermia nullifies the ameliorating effect of dizocilpine maleate (MK-801) in focal cerebral ischemia

1995 • 97 citations

Effect of mild hyperthermia on recovery of metabolic function after global cerebral ischemia in cats.

1988 • 88 citations

Hyperthermia enhances spectrin breakdown in transient focal cerebral ischemia

1997 • 77 citations

The influence of body temperature on infarct volume and thrombolytic therapy in a rat embolic stroke model

1994 • 73 citations

Effect of mild hyperthermia on recovery of metabolic function after global cerebral ischemia in cats.

1988 • 53 citations

Ischemia-Induced Neurotransmitter Release: Effects of Mild Intraischemic Hyperthermia

1992 • 34 citations

Delayed Posttraumatic Brain Hyperthermia Worsens Outcome after Fluid Percussion Brain Injury: A Light and Electron Microscopic Study in Rats

1996 • 30 citations

Effects of Brain Temperature on Calmodulin and Microtubuleassociated Protein 2 Immunoreactivity in the Gerbil Hippocampus Following Transient Forebrain Ischemia

1997 • 26 citations

Drug research related to neuroactive amino acids: Alfred Benzon Symposium 32

1992 • 21 citations