Study of the modulatory activity of bz (ω) receptor ligands on defensive behaviors in mice: Evaluation of the importance of intrinsic efficacy and receptor subtype selectivity

Structure and pharmacology of gamma-aminobutyric acidA receptor subtypes.

1995 • 1,277 citations

γ‐Aminobutyric Acid_A Receptor α₅‐Subunit Creates Novel Type II Benzodiazepine Receptor Pharmacology

1990 • 498 citations

Some properties of brain specific benzodiazepine receptors: New evidence for multiple receptors

1979 • 412 citations

Defense system psychopharmacology: An ethological approach to the pharmacology of fear and anxiety

1993 • 359 citations

A synthetic non-benzodiazepine ligand for benzodiazepine receptors: A probe for investigating neuronal substrates of anxiety

1979 • 284 citations

Novel anxiolytics that act as partial agonists at benzodiazepine receptors

1990 • 276 citations

Zolpidem, a novel nonbenzodiazepine hypnotic. I. Neuropharmacological and behavioral effects.

1986 • 274 citations

GABAA/Benzodiazepine receptor heterogeneity: Neurophysiological implications

1995 • 245 citations

An ethological analysis of the effects of chlordiazepoxide and bretazenil (Ro 16???6028) in the murine elevated plus-maze

1993 • 171 citations

Recent developments in the behavioral pharmacology of benzodiazepine (ω) receptors: Evidence for the functional significance of receptor subtypes

1994 • 158 citations

Differences in affinity and efficacy of benzodiazepine receptor ligands at recombinant gamma-aminobutyric acidA receptor subtypes.

1993 • 149 citations

Imidazopyridines as a tool for the characterization of benzodiazepine receptors: A proposal for a pharmacological classification as omega receptor subtypes

1988 • 146 citations

Abecarnil, a metabolically stable, anxioselective beta-carboline acting at benzodiazepine receptors.

1990 • 130 citations

Affinity of various ligands for benzodiazepine receptors in rat cerebellum and hippocampus

1984 • 92 citations

Ro 16-6028: A Novel Anxiolytic Acting as a Partial Agonist at the Benzodiazepine Receptor

1988 • 91 citations

Differences in pharmacological profiles of a new generation of benzodiazepine and non-benzodiazepine hypnotics

1990 • 91 citations

The use of the rat elevated plus-maze to discriminate between non-selective and BZ-1 (ω 1) selective, benzodiazepine receptor ligands

1996 • 87 citations

Imidazenil: a new partial positive allosteric modulator of gamma-aminobutyric acid (GABA) action at GABAA receptors.

1993 • 85 citations

Relationship between benzodiazepine receptor occupancy and functional effects in vivo of four ligands of differing intrinsic efficacies.

1992 • 82 citations

Molecular mechanisms of the partial allosteric modulatory effects of bretazenil at gamma-aminobutyric acid type A receptor.

1992 • 79 citations

A model of ???antipredator??? defense in Swiss-Webster mice

1995 • 78 citations

Full and partial agonism displayed by benzodiazepine receptor ligands at recombinant gamma-aminobutyric acidA receptor subtypes.

1993 • 64 citations

Genetic differences in the mouse defense test battery

1997 • 60 citations

Behavioural effects of novel benzodiazepine (omega) receptor agonists and partial agonists: increases in punished responding and antagonism of the pentylenetetrazole cue.

1995 • 59 citations

Comparison of several benzodiazepine receptor ligands in two models of anxiolytic activity in the mouse: an analysis based on fractional receptor occupancies

1994 • 57 citations

Expression and properties of recombinant α1β2γ2 and α5β2γ2 forms of the rat GABAA receptor

1993 • 57 citations

Pharmacological characterization of benzodiazepine receptor ligands with intrinsic efficacies ranging from high to zero

1993 • 53 citations

5-HT1A agonists modulate mouse antipredator defensive behavior differently from the 5-HT2A antagonist pirenperone

1995 • 49 citations

Relationship between benzodiazepine receptor occupancy and potentiation of gamma-aminobutyric acid-stimulated chloride flux in vitro of four ligands of differing intrinsic efficacies.

1992 • 44 citations

Behavioural effects of novel benzodiazepine (??) receptor agonists and partial agonists

1995 • 43 citations

Further evidence for differences between non-selective and BZ-1 (ω1) Selective, benzodiazepine receptor ligands in murine models of “state” and “trait” Anxiety

1996 • 40 citations

Abecarnil is a Full Agonist at Some, and a Partial Agonist at Other Recombinant GABAA Receptor Subtypes

1993 • 35 citations

Pharmacological Characterization of the Novel Anxiolytic β-Carboline Abecarnil in Rodents and Primates

1994 • 33 citations

Ro 19-8022, a nonbenzodiazepine partial agonist at benzodiazepine receptors: neuropharmacological profile of a potential anxiolytic.

1992 • 32 citations

Target Receptors for Anxiolytics and Hypnotics: From Molecular Pharmacology to Therapeutics

1992 • 31 citations

The mouse defense test battery: evaluation of the effects of non-selective and BZ-1 (omega1) selective, benzodiazepine receptor ligands.

1996 • 28 citations

Effect of the beta-carboline abecarnil on spinal reflexes in mice and on muscle tone in genetically spastic rats: a comparison with diazepam.

1993 • 19 citations

Behavioral and biochemical characterization of benzodiazepine receptor partial agonists in pigeons.

1996 • 10 citations

Benzodiazepine (ω) receptor partial agonists and the acquisition of conditioned fear in mice

1995 • 7 citations

Anxiolytic β-Carbolines

1993 • 7 citations

Abecarnil enhances GABA-induced currents in acutely isolated cerebellar Purkinje cells

1995 • 7 citations