In Vitro Analysis of Murine B-Cell Development

Somatic generation of antibody diversity

1983 • 3,275 citations

Plaque Formation in Agar by Single Antibody-Producing Cells

1963 • 2,385 citations

Conditions controlling the proliferation of haemopoietic stem cells in vitro

1977 • 2,157 citations

IMMUNIZATION OF DISSOCIATED SPLEEN CELL CULTURES FROM NORMAL MICE

1967 • 2,062 citations

A plaque assay for all cells secreting Ig of a given type or class

1976 • 1,034 citations

Biology of the Laboratory Mouse

1941 • 826 citations

Ordered rearrangement of immunoglobulin heavy chain variable region segments.

1984 • 736 citations

Two mRNAs with different 3′ ends encode membrane-bound and secreted forms of immunoglobulin μ chain

1980 • 659 citations

Long-term culture of B lymphocytes and their precursors from murine bone marrow.

1982 • 612 citations

Complete replacement of serum by albumin, transferrin, and soybean lipid in cultures of lipopolysaccharide-reactive B lymphocytes.

1978 • 535 citations

B220: a B cell-specific member of the T200 glycoprotein family

1981 • 525 citations

Organization and reorganization of immunoglobulin genes in A-MuLV-transformed cells: Rearrangement of heavy but not light chain genes

1981 • 497 citations

Prostaglandin E production by human blood monocytes and mouse peritoneal macrophages.

1978 • 489 citations

A RECEPTOR FOR ANTIBODY ON B LYMPHOCYTES

1972 • 469 citations

Lymphosarcoma: virus-induced thymic-independent disease in mice.

1970 • 414 citations

Murine B Cell Leukemia Line with Inducible Surface Immunoglobulin Expression

1978 • 388 citations

Clonal growth and maturation to immunoglobulin secretion in vitro of every growth-inducible B lymphocyte

1977 • 309 citations

An immunoglobulin heavy-chain gene is formed by at least two recombinational events

1980 • 306 citations

SURFACE ALLOANTIGENS OF PLASMA CELLS

1970 • 281 citations

Continuing kappa-gene rearrangement in a cell line transformed by Abelson murine leukemia virus

1982 • 278 citations

THE MECHANISM OF ANTIGENIC STIMULATION OF PRIMARY AND SECONDARY CLONAL PRECURSOR CELLS

1972 • 272 citations

Immunoglobulin synthesis by lymphoid cells transformed in vitro by Abelson murine leukemia virus

1979 • 243 citations

Sensitivity of corticosteroid-dependent insulin-resistant lipogenesis in marrow preadipocytes of obese-diabetic (db/db) mice

1978 • 231 citations

Functional status of cells from lymphoid and myeloid tissues in mice with severe combined immunodeficiency disease.

1984 • 229 citations

Rearrangement of immunoglobulin gamma 1-chain gene and mechanism for heavy-chain class switch.

1980 • 213 citations

Sequential Expression of Immunoglobulin on Developing Mouse B Lymphocytes: A Systematic Survey That Suggests a Model for the Generation of Immunoglobulin Isotype Diversity

1978 • 211 citations

Cell surface immunoglobulin. XI. The appearance of an IgD-like molecule on murine lymphoid cells during ontogeny.

1975 • 200 citations

Proliferation of Haemopoietic Stem Cells in Vitro

1974 • 181 citations

Growth of B-lymphocyte colonies in vitro.

1975 • 173 citations

Immunoglobulin Gene Rearrangement in Immature B Cells

1980 • 172 citations

Mouse pre-B cells synthesize and secrete heavy chains but not light chains

1980 • 171 citations

Candidate for immunoglobulin D present on murine B lymphocytes

1974 • 170 citations

Induction of antibody‐forming cell clones in microcultures

1972 • 155 citations

Studies on the Generation of B Lymphocytes in Fetal Liver and Bone Marrow

1977 • 150 citations

Formation of B Lymphocytes in Fetal and Adult Life

1981 • 135 citations

Lymphoid tissue architecture. II. Ontogeny of peripheral T and B cells in mice: evidence against Peyer's patches as the site of generation of B cells.

1974 • 127 citations

Biosynthesis and Regulation of Immunoglobulins

1983 • 119 citations

Somatic mutation creates diversity in the major group of mouse immunoglobulin kappa light chains.

1984 • 117 citations

Cell surface antigens expressed by subsets of pre-B cells and B cells.

1984 • 111 citations

Growth of B-lymphocytes clones in semisolid culture is mitogen dependent.

1976 • 111 citations

Ontogeny of murine B lymphocytes: sequence of B-cell differentiation from surface-immunoglobulin-negative precursors to plasma cells.

1976 • 110 citations

The fate of fetal and adult B-cell progenitors grafted into immunodeficient CBA/N mice.

1979 • 107 citations

The B-Cell Clonotype Repertoire

1978 • 95 citations

B‐Lymphocyte Subpopulations in the Mouse

1975 • 92 citations

Murine embryonic B lymphocyte development in the placenta

1979 • 83 citations

Antibody with homogeneous antigen binding produced by splenic foci in organ culture

1969 • 81 citations

B lymphocyte development in fetal liver

1977 • 78 citations

Long-term culture of normal mouse B lymphocytes.

1981 • 73 citations

The ontogeny of murine B lymphocytes. I. Induction of phenotypic conversion of Ia-to Ia+ lymphocytes.

1975 • 72 citations

In vitro studies on lymphocyte differentiation. I. Long term in vitro culture of cells giving rise to functional lymphocytes in irradiated mice.

1978 • 68 citations

Terminal deoxynucleotidyltransferase. Serological studies and radioimmunoassay.

1976 • 61 citations

The Stimulation of Splenic Foci in Vitro

1971 • 56 citations

Isotype switching in murine pre-B cell lines

1983 • 55 citations

Surface immunoglobulin-negative B-cell precursors detected by formation of antibody-secreting colonies in agar

1983 • 55 citations

Preferential but Nonexclusive Expression of Macromolecular Antigens on B‐Lineage Cells

1983 • 54 citations

Functional V region formation during in vitro culture of a murine immature B precursor cell line

1983 • 52 citations

Abelson Leukemia Virus

1982 • 50 citations

Spontaneous in vitro occurrence and long-term culture of murine B lymphoblast cell lines.

1983 • 49 citations

Maturational state of lymphoid cells in long-term bone marrow cultures.

1982 • 45 citations

Cell interactions between hematopoietic and stromal cells in the embryonic chick bone marrow

1980 • 42 citations

B lymphocyte development in fetal liver

1977 • 41 citations

Long-term cultures of murine fetal liver retain very early B lymphoid phenotype.

1984 • 39 citations

Induction of proliferation and differentiation of neoplastic B cells by anti-immunoglobulin and T-cell factors.

1981 • 36 citations

Characterization of murine colony-forming B cells. II. Limits to in vitro maturation, Lyb-2 expression, resolution of IgD+ subsets, and further population analysis.

1980 • 34 citations

Ultrastructural studies of erythroblastic islands of rat bone marrow. II. The resumption of erythropoiesis in erythropoietically depressed rebound marrow.

1972 • 34 citations

Appearance of Functional Lymphocytes in Fetal Liver

1976 • 33 citations

Ontogenic development of B-lymphocyte function and tolerance susceptibility in vivo and in an in vitro organ culture system.

1980 • 31 citations

Plasmacytomas, lymphomas and hybridomas: Their contribution to immunology and molecular biology

1980 • 25 citations

kappa gene diversity among the clonal progeny of pre-B lymphocytes.

1984 • 17 citations

An investigation into the B lymphopoietic capacity of long-term bone marrow cultures.

1983 • 14 citations

B-lymphocyte ontogeny.

1981 • 9 citations