Properties of HERG Channels Stably Expressed in HEK 293 Cells Studied at Physiological Temperature
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References (42)
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
1970 • 253,849 citations
Molecular Cloning: A Laboratory Manual
2001 • 133,517 citations
Molecular cloning: A laboratory manual
1990 • 85,659 citations
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 • 47,043 citations
Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
1981 • 18,584 citations
Down-Regulation of Na+/K+ATPase Activity by Human Parvovirus B19 Capsid Protein VP1
2013 • 8,607 citations
Regulation of the Voltage Gated K<sup>+</sup> Channel K<sub>v1.3</sub> by Recombinant Human Klotho Protein
2014 • 5,592 citations
The effect of sodium ions on the electrical activity of the giant axon of the squid
1949 • 3,479 citations
POTENTIAL, IMPEDANCE, AND RECTIFICATION IN MEMBRANES
1943 • 2,733 citations
A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel
1995 • 2,391 citations
A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome
1995 • 2,263 citations
Coassembly of KVLQT1 and minK (IsK) proteins to form cardiac IKS potassium channel
1996 • 1,741 citations
Two components of cardiac delayed rectifier K+ current. Differential sensitivity to block by class III antiarrhythmic agents.
1990 • 1,467 citations
HERG, a Human Inward Rectifier in the Voltage-Gated Potassium Channel Family
1995 • 1,216 citations
A family of potassium channel genes related to eag in Drosophila and mammals.
1994 • 960 citations
The G-protein-gated atrial K+ channel IKAch is a heteromultimer of two inwardly rectifying K+-channel proteins
1995 • 830 citations
The inward rectification mechanism of the HERG cardiac potassium channel
1996 • 754 citations
Characteristics of the Delayed Rectifier Current (IKrand IKs) in Canine Ventricular Epicardial, Midmyocardial, and Endocardial Myocytes
1995 • 605 citations
Sustained depolarization-induced outward current in human atrial myocytes. Evidence for a novel delayed rectifier K+ current similar to Kv1.5 cloned channel currents.
1993 • 568 citations
Spectrum of HERG K+-channel dysfunction in an inherited cardiac arrhythmia.
1996 • 465 citations
Evidence for Two Components of Delayed Rectifier K + Current in Human Ventricular Myocytes
1996 • 463 citations
Fast inactivation causes rectification of the IKr channel.
1996 • 395 citations
Two Isoforms of the Mouse Ether-a-go-go –Related Gene Coassemble to Form Channels With Properties Similar to the Rapidly Activating Component of the Cardiac Delayed Rectifier K + Current
1997 • 289 citations
Class III Antiarrhythmic Drugs Block HERG, a Human Cardiac Delayed Rectifier K + Channel
1996 • 288 citations
A rapidly activating and slowly inactivating potassium channel cloned from human heart. Functional analysis after stable mammalian cell culture expression.
1993 • 265 citations
A quantitative analysis of the activation and inactivation kinetics of HERG expressed in Xenopus oocytes
1997 • 252 citations
High affinity open channel block by dofetilide of HERG expressed in a human cell line.
1996 • 243 citations
Rapid and slow components of delayed rectifier current in human atrial myocytes
1994 • 236 citations
Blockage of the HERG human cardiac K+ channel by the gastrointestinal prokinetic agent cisapride
1997 • 225 citations
Molecular Physiology and Pharmacology of HERG
1996 • 205 citations
Rapid Inactivation Determines the Rectification and [K + ] o Dependence of the Rapid Component of the Delayed Rectifier K + Current in Cardiac Cells
1997 • 164 citations
Palmitylation, sulfation, and glycosylation of the alpha subunit of the sodium channel. Role of post-translational modifications in channel assembly.
1987 • 161 citations
Effects of Delayed Rectifier Current Blockade by E-4031 on Impulse Generation in Single Sinoatrial Nodal Myocytes of the Rabbit
1995 • 131 citations
Adrenergic Modulation of Ultrarapid Delayed Rectifier K+ Current in Human Atrial Myocytes
1996 • 124 citations
Glycosylation of Shaker Potassium Channel Protein in Insect Cell Culture and in Xenopus Oocytes
1994 • 118 citations
Four Novel KVLQT1 and Four Novel HERG Mutations in Familial Long-QT Syndrome
1997 • 117 citations
The brain Kv1.1 potassium channel: in vitro and in vivo studies on subunit assembly and posttranslational processing
1994 • 108 citations
K+ currents and K+ channel mRNA in cultured atrial cardiac myocytes (AT-1 cells).
1994 • 75 citations
Delayed Rectifier Channels in Human Ventricular Myocytes
1995 • 74 citations
Activation and inactivation kinetics of an E-4031-sensitive current from single ferret atrial myocytes
1996 • 70 citations
A quantitative description of the E-4031-sensitive repolarization current in rabbit ventricular myocytes
1995 • 48 citations
HERG Sequence Correction
1996 • 19 citations