An AML-1 consensus sequence binds an osteoblast-specific complex and transcriptionally activates the osteocalcin gene.

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Current Protocols in Molecular Biology

1989 • 1,916 citations

PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AML1 gene.

1993 • 621 citations

Two Distinct Osteoblast-Specific cis-Acting Elements Control Expression of a Mouse Osteocalcin Gene

1995 • 564 citations

Factors that promote progressive development of the osteoblast phenotype in cultured fetal rat calvaria cells

1990 • 515 citations

Molecular Cloning and Characterization of PEBP2β, the Heterodimeric Partner of a Novel Drosophila runt-Related DNA Binding Protein PEBP2α

1993 • 504 citations

Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions.

1993 • 484 citations

Parathyroid Hormone-Responsive Clonal Cell Lines from Rat Osteosarcoma*

1980 • 483 citations

Cloning and Characterization of Subunits of the T-Cell Receptor and Murine Leukemia Virus Enhancer Core-Binding Factor

1993 • 425 citations

The t(8;21) Fusion Protein Interferes with AML-1B-Dependent Transcriptional Activation

1995 • 391 citations

The runt domain identifies a new family of heterometric transcriptional regulators

1993 • 331 citations

PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBP2 beta/CBF beta proto-oncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature myeloid cells.

1994 • 315 citations

Normal rat cell lines deficient in nuclear thymidine kinase

1981 • 307 citations

The Tissue-Specific Nuclear Matrix Protein, NMP-2, Is a Member of the AML/PEBP2/Runt Domain Transcription Factor Family: Interactions with the Osteocalcin Gene Promoter

1995 • 245 citations

Isolation of PEBP2 alpha B cDNA representing the mouse homolog of human acute myeloid leukemia gene, AML1.

1993 • 229 citations

Purification of a mouse nuclear factor that binds to both the A and B cores of the polyomavirus enhancer

1990 • 218 citations

Coordinate occupancy of AP-1 sites in the vitamin D-responsive and CCAAT box elements by Fos-Jun in the osteocalcin gene: model for phenotype suppression of transcription.

1990 • 209 citations

Identification of a region which directs the monocytic activity of the colony-stimulating factor 1 (macrophage colony-stimulating factor) receptor promoter and binds PEBP2/CBF (AML1).

1994 • 207 citations

Purification of core-binding factor, a protein that binds the conserved core site in murine leukemia virus enhancers.

1992 • 194 citations

Mutation of the core or adjacent LVb elements of the Moloney murine leukemia virus enhancer alters disease specificity.

1990 • 178 citations

Receptors for 1,25(OH)₂‐vitamin D₃ enriched in cloned osteoblast‐like rat osteogenic sarcoma cells

1980 • 167 citations

Osteocalcin gene promoter-binding factors are tissue-specific nuclear matrix components.

1993 • 166 citations

Expression of the Runt Domain-Encoding PEBP2α Genes in T cells during Thymic Development

1995 • 160 citations

Vitamin D-mediated modifications in protein-DNA interactions at two promoter elements of the osteocalcin gene.

1990 • 147 citations

Transcriptional control of the tissue-specific, developmentally regulated osteocalcin gene requires a binding motif for the Msx family of homeodomain proteins.

1994 • 133 citations

Functional dissection of the lck proximal promoter.

1992 • 120 citations

Identification and functional characterization of the human T-cell receptor beta gene transcriptional enhancer: common nuclear proteins interact with the transcriptional regulatory elements of the T-cell receptor alpha and beta genes.

1990 • 117 citations

Sequence specificity of the core-binding factor

1993 • 108 citations

Differential protein binding in lymphocytes to a sequence in the enhancer of the mouse retrovirus SL3-3.

1988 • 108 citations

Indistinguishable nuclear factor binding to functional core sites of the T-cell receptor delta and murine leukemia virus enhancers.

1992 • 102 citations

The murine myeloperoxidase promoter contains several functional elements, one of which binds a cell type-restricted transcription factor, myeloid nuclear factor 1 (MyNF1).

1993 • 98 citations

Identification of AML-1 and the (8;21) Translocation Protein (AML-1/ETO) as Sequence-Specific DNA-Binding Proteins: theruntHomology Domain is Required for DNA Binding and Protein-Protein Interactions

1993 • 90 citations

Phosphatidylinositol 3-kinase activation is mediated by high-affinity interactions between distinct domains within the p110 and p85 subunits

1994 • 90 citations

Transforming growth factor-beta 1 responsiveness of the rat osteocalcin gene is mediated by an activator protein-1 binding site.

1996 • 77 citations

DNase I hypersensitive sites in promoter elements associated with basal and vitamin D dependent transcription of the bone-specific osteocalcin gene

1994 • 65 citations

Purification of Core-Binding Factor, a Protein That Binds the Conserved Core Site in Murine Leukemia Virus Enhancers

1992 • 65 citations

Differential Protein Binding in Lymphocytes to a Sequence in the Enhancer of the Mouse Retrovirus SL3-3

1988 • 60 citations

PEBP2/CBF, the Murine Homolog of the Human Myeloid AML1 and PEBP2β/CBFβ Proto-oncoproteins, Regulates the Murine Myeloperoxidase and Neutrophil Elastase Genes in Immature Myeloid Cells

1994 • 52 citations

Identification of a Region Which Directs the Monocytic Activity of the Colony-Stimulating Factor 1 (Macrophage Colony-Stimulating Factor) Receptor Promoter and Binds PEBP2/CBF (AML1)

1994 • 52 citations

Functional Dissection of the lck Proximal Promoter

1992 • 51 citations

Differential Expression of Subspecies of Polyomavirus and Murine Leukemia Virus Enhancer Core Binding Protein, PEBP2, in Various Hematopoietic Cells

1992 • 46 citations

Identification and Functional Characterization of the Human T-Cell Receptor β Gene Transcriptional Enhancer: Common Nuclear Proteins Interact with the Transcriptional Regulatory Elements of the T-Cell Receptor α and β Genes

1990 • 42 citations

A transcriptional enhancer of the mouse T cell receptor δ gene locus

1991 • 34 citations

The Murine Myeloperoxidase Promoter Contains Several Functional Elements, One of Which Binds a Cell Type-Restricted Transcription Factor, Myeloid Nuclear Factor 1 (MyNF1)

1993 • 27 citations

Indistinguishable Nuclear Factor Binding to Functional Core Sites of the T-Cell Receptor δ and Murine Leukemia Virus Enhancers

1992 • 24 citations

The Polyomavirus Enhancer Activates Chromatin Accessibility on Integration into the HPRT Gene

1992 • 23 citations