Cis-trans recognition and subunit-specific degradation of short-lived proteins

Current protocols in molecular biology

1988 • 4,543 citations

In Vivo Half-Life of a Protein Is a Function of Its Amino-Terminal Residue

1986 • 1,942 citations

Intracellular Protein Degradation in Mammalian and Bacterial Cells

1974 • 1,775 citations

Cyclin: A protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division

1983 • 1,506 citations

A Multiubiquitin Chain Is Confined to Specific Lysine in a Targeted Short-Lived Protein

1989 • 1,463 citations

The role of cyclin synthesis and degradation in the control of maturation promoting factor activity

1989 • 1,114 citations

[10] Yeast promoters and lacZ fusions designed to study expression of cloned genes in yeast

1983 • 1,095 citations

The molecular genetics of embryonic pattern formation in Drosophila

1988 • 1,048 citations

Universality and Structure of the N-end Rule

1989 • 472 citations

Ubiquitin-mediated protein degradation.

1988 • 453 citations

The degradation signal in a short-lived protein

1989 • 427 citations

Defective presentation to class I-restricted cytotoxic T lymphocytes in vaccinia-infected cells is overcome by enhanced degradation of antigen.

1988 • 331 citations

The segmentation and homeotic gene network in early Drosophila development

1987 • 286 citations

In vivo degradation of a transcriptional regulator: The yeast α2 repressor

1990 • 243 citations

a1 Protein alters the dna binding specificity of α2 repressor

1988 • 218 citations

Specificity of binding of NH2-terminal residue of proteins to ubiquitin-protein ligase. Use of amino acid derivatives to characterize specific binding sites.

1988 • 144 citations

Role of arginine-tRNA in protein degradation by the ubiquitin pathway

1987 • 142 citations

Action of leucine zippers

1989 • 130 citations

A study of the urea-produced subunits of β-galactosidase

1963 • 92 citations

Turnover of mitochondrial inner membrane proteins in hepatoma monolayer cultures.

1982 • 55 citations

On the effect of divalent cations and protein concentration upon renaturation of β-galactosidase from E. coli

1969 • 51 citations

The effect of urea on subunit interactions of ß-galactosidase from Escherichia coli K12

1967 • 31 citations

Effect of limited digestion by proteolytic enzymes on Escherichia coli β-galactosidase

1966 • 17 citations

The N-End Rule of Selective Protein Turnover

1988 • 12 citations