Gradual Changes in Permeability of Inner Mitochondrial Membrane Precede the Mitochondrial Permeability Transition

The mitochondrial permeability transition

1995 • 2,412 citations

Mechanisms by which mitochondria transport calcium

1990 • 1,630 citations

Role of calcium ions in regulation of mammalian intramitochondrial metabolism

1990 • 1,369 citations

Mitochondrial control of nuclear apoptosis.

1996 • 1,363 citations

The Ca2+-induced membrane transition in mitochondria

1979 • 751 citations

ATP-sensitive K+ channel in the mitochondrial inner membrane

1991 • 746 citations

Relationship between configuration, function, and permeability in calcium-treated mitochondria.

1976 • 610 citations

Recent progress on regulation of the mitochondrial permeability transition pore; a cyclosporin-sensitive pore in the inner mitochondrial membrane

1994 • 561 citations

Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore by the proton electrochemical gradient. Evidence that the pore can be opened by membrane depolarization.

1992 • 443 citations

The regulation of the matrix volume of mammalian mitochondria in vivo and in vitro and its role in the control of mitochondrial metabolism

1989 • 443 citations

The permeability transition pore. Control points of a cyclosporin A-sensitive mitochondrial channel involved in cell death

1996 • 420 citations

The regulation of extramitochondrial free calcium ion concentration by rat liver mitochondria

1978 • 380 citations

Reconstitution and partial purification of the glibenclamide-sensitive, ATP-dependent K+ channel from rat liver and beef heart mitochondria.

1992 • 358 citations

The relationship between mitochondrial membrane permeability, membrane potential, and the retention of Ca2+ by mitochondria.

1980 • 288 citations

The Mitochondrial Permeability Transition Pore is Modulated by Oxidative Agents Through Both Pyridine Nucleotides and Glutathione at Two Separate Sites

1996 • 233 citations

Mechanistic studies of lantibiotic-induced permeabilization of phospholipid vesicles

1995 • 232 citations

Cation transport in mitochondria — The potassium cycle

1996 • 208 citations

Regulation of the permeability transition pore, a voltage-dependent mitochondrial channel inhibited by cyclosporin A

1994 • 208 citations

Integration of Mitochondrial Function

1988 • 165 citations

Oscillatory states of mitochondria

1966 • 162 citations

Effects of phospholipase A2 inhibitors on ruthenium red-induced Ca2+ release from mitochondria.

1985 • 160 citations

Correlation Between H⁺ and Anion Movement in Mitochondria and the Key Role of the Phosphate Carrier

1971 • 155 citations

Metabolic and Structural States of Mitochondria

1960 • 147 citations

Recurrent ischemia in the canine heart causes recurrent bursts of free radical production that have a cumulative effect on contractile function. A pathophysiological basis for chronic myocardial "stunning".

1995 • 125 citations

Phenylarsine oxide induces the cyclosporin A-sensitive membrane permeability transition in rat liver mitochondria

1991 • 114 citations

[12] Bromobimane probes for thiols

1995 • 113 citations

Modulation of the Mitochondrial Permeability Transition by Nitric Oxide

1997 • 112 citations

Increased permeability of mitochondria during Ca2+ release induced by t-butyl hydroperoxide or oxalacetate. the effect of ruthenium red.

1982 • 109 citations

On the regulation of K+ uniport in intact mitochondria by adenine nucleotides and nucleotide analogs.

1993 • 104 citations

Energy-dependent exchange of K+ in heart mitochondria K+ influx

1977 • 103 citations

Avoiding reperfusion injury after limb revascularization: Experimental observations and recommendations for clinical application

1989 • 96 citations

Effect of Transport-Inducing Antibiotics and Other Agents on Potassium Flux in Mitochondria^*

1967 • 81 citations

Oscillatory states of mitochondria

1967 • 81 citations

Permeability transition pore of the inner mitochondrial membrane can operate in two open states with different selectivities

1996 • 79 citations

Optical rotary dispersion and circular dichroism studies on mitochondria: Correlation of ultrastructure and metabolic state with molecular conformational changes

1968 • 63 citations

Estimation of matrix pH in isolated heart mitochondria using a fluorescent probe

1989 • 58 citations

Potassium Channel Opener, RP 66471, Induces Membrane Depolarization of Rat Liver Mitochondria

1995 • 56 citations

Cardiac Recovery during Postischemic Reperfusion Is Improved by Combination of Vitamin E with Dihydrolipoic Acid

1993 • 52 citations

Ion permeability induction by the SH cross-linking reagents in rat liver mitochondria is inhibited by the free radical scavenger, butylhydroxytoluene

1987 • 50 citations

Flupirtine protects neurons against excitotoxic or ischemic damage and inhibits the increase in cytosolic Ca2+ concentration

1995 • 50 citations

The Role of Mitochondrial Potassium Fluxes in Controlling the Protonmotive Force in Energized Mitochondria

1995 • 49 citations

Oscillatory states of mitochondria

1967 • 37 citations

The K+ conductance of the inner mitochondrial membrane. A study of the inducible uniport for monovalent cations

1991 • 37 citations

The relation of respiration-dependent proton transfer to mitochondrial structure

1969 • 36 citations

The effect of Ca2+ and acyl coenzyme A:lysophospholipid acyltransferase inhibitors on permeability properties of the liver mitochondrial inner membrane.

1986 • 34 citations

ATP-regulated K+ channel in mitochondria: Pharmacology and function

1996 • 34 citations

Electron microscopic studies: importance of embedding techniques in quantitative evaluation of cardiac mitochondrial structure during regional ischemia and reperfusion.

1986 • 32 citations

Mitochondria: DNA proteins and disease

1995 • 32 citations

Mitochondria: DNA proteins and disease

1994 • 29 citations

STUDIES OF CONTROLLED REPERFUSION AFTER ISCHEMIA

1986 • 25 citations

Ca²⁺‐triggered membrane permeability transition in deenergized mitochondria from rat liver

1995 • 23 citations

Dose/response curves of lipoic acid R- and S-forms in the working rat heart during reoxygenation: Superiority of the R-enantiomer in enhancement of aortic flow

1995 • 22 citations

Demonstration of glibenclamide-sensitive K+ fluxes in rat liver mitochondria.

1993 • 21 citations

Oligomycin and ADP sensitivity of in vitro alkylation of SH‐groups in rat liver mitochondria

1970 • 21 citations

Extensive Ca2+ release from energized mitochondria induced by disulfiram

1989 • 18 citations

2-mercaptopropionylglycine improves aortic flow after reoxygenation in working rat hearts

1988 • 18 citations

Generation of the mitochondrial permeability transition does not involve inhibition of lysophospholipid acylation. Acyl-coenzyme A:1-acyllysophospholipid acyltransferase activity is not found in rat liver mitochondria.

1991 • 18 citations

Studies of hypoxemic/reoxygenation injury: Without aortic clamping

1995 • 17 citations

pH-Dependent conformational changes in submitochondrial particles

1969 • 17 citations

Effect of the triaminopyridine flupirtine on calcium uptake, membrane potential and ATP synthesis in rat heart mitochondria

1998 • 17 citations

Oligomycin sensitivity of mitochondrial sulfhydryl groups

1977 • 15 citations

Cardioprotective potency of the radical scavenger S-2-(3 aminopropylamino) ethylphosphorothioic acid in the post-ischaemic rat heart

1995 • 13 citations

Interaction of bromosulfophthalein with mitochondrial membranes: Effect on ion movements

1977 • 13 citations

A multiparameter analysis of the perfused rat heart: Responses to ischemia, uncouplers and drugs

1987 • 13 citations

Influence of pH on sulfhydryl groups and fluidity of the mitochondrial membrane

1990 • 12 citations

31P-NMR spectroscopic investigations and mitochondrial studies on the cardioprotective efficiency of 2-mercartopropionylglycine

1986 • 11 citations

Tracking of proton flow during transition from anaerobiosis to steady state

1991 • 11 citations

Inhibition of membrane-bound succinate dehydrogenase by disulfiram

1991 • 10 citations

2‐Mercaptopropionylglycine restores activity of oligomycin‐sensitive ATPase to control values following treatment with carbonylcyanide‐P‐trifluoromethoxyphenylhydrazone

1979 • 9 citations

Swelling of rat liver mitochondria with N‐(N‐acetyl‐4‐sulphamoylphenyl)‐maleimide

1968 • 9 citations

Correlations of ATPase Activity and ATP Levels with Structural Alterations in Rat Liver Mitochondria during Swelling

1969 • 5 citations