Flupirtine protects neurons against excitotoxic or ischemic damage and inhibits the increase in cytosolic Ca2+ concentration

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Glutamate neurotoxicity and diseases of the nervous system

1988 • 7,257 citations

Excitotoxity and the NMDA receptor

1987 • 1,053 citations

The role of calcium in cell death

1981 • 637 citations

Glutamate receptor-induced 45Ca2+ accumulation in cortical cell culture correlates with subsequent neuronal degeneration

1993 • 396 citations

Multiple apparent alpha-noradrenergic receptor binding sites in rat brain: effect of 6-hydroxydopamine.

1979 • 362 citations

Multiple apparent alpha-noradrenergic receptor binding sites in rat brain: effect of 6-hydroxydopamine.

1979 • 199 citations

Effect of Lactacidosis on Pyridine Nucleotide Stability During Ischemia in Mouse Brain

1987 • 140 citations

Opiate- and alpha 2-adrenoceptor-induced hyperpolarizations of locus ceruleus neurons in brain slices: reversal by cyclic adenosine 3':5'- monophosphate analogues

1985 • 132 citations

A mouse model of focal cerebral ischemia for screening neuroprotective drug effects

1992 • 91 citations

Neurodegenerative disorders; mechanisms and prospects for therapy

1992 • 60 citations

N-methyl-D-aspartate (NMDA)-mediated muscle relaxant action of flupirtine in rats

1994 • 43 citations

Immunohistochemical evidence for flupirtine acting as an antagonist on theN-methyl-d-aspartate and homocysteic acid-induced release of GABA in the rabbit retina

1994 • 38 citations

[The pharmacologic effect of flupirtine, a structurally new analgesic].

1985 • 21 citations

[The effect of flupirtine, various analgesics and muscle relaxants on skeletal muscle tone in the conscious rat].

1990 • 21 citations

Possible involvement of noradrenergic descending pain-modulating pathways in the mode of antinociceptive action of flupirtine, a novel non-opioid analgesic

1988 • 13 citations