Multiple Adenosine 3′,5′- Monophosphate Response Element DNA-Binding Proteins Generated by Gene Diversification and Alternative Exon Splicing

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

1987 • 3,057 citations

Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133

1989 • 2,486 citations

Improved technique utilizing nonfat dry milk for analysis of proteins and nucleic acids transferred to nitrocellulose

1984 • 1,697 citations

Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

1986 • 1,424 citations

Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene

1987 • 1,364 citations

Human Proto-Oncogene c- jun Encodes a DNA Binding Protein with Structural and Functional Properties of Transcription Factor AP-1

1987 • 1,353 citations

Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers.

1989 • 1,046 citations

A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence

1989 • 914 citations

Evidence That the Leucine Zipper Is a Coiled Coil

1989 • 869 citations

DNA binding activities of three murine Jun proteins: Stimulation by Fos

1988 • 850 citations

The role of the leucine zipper in the fos–jun interaction

1988 • 836 citations

Cyclic AMP-Responsive DNA-Binding Protein: Structure Based on a Cloned Placental cDNA

1988 • 772 citations

12-O-tetradecanoyl-phorbol-13-acetate induction of the human collagenase gene is mediated by an inducible enhancer element located in the 5'-flanking region.

1987 • 699 citations

Molecular cloning of an enhancer binding protein:Isolation by screening of an expression library with a recognition site DNA

1988 • 677 citations

jun-B inhibits and c-fos stimulates the transforming and trans-activating activities of c-jun

1989 • 488 citations

jun-D: a third member of the jun gene family.

1989 • 469 citations

Two tobacco DNA-binding proteins with homology to the nuclear factor CREB

1989 • 462 citations

Tissue-specific enhancer of the human glycoprotein hormone alpha-subunit gene: dependence on cyclic AMP-inducible elements.

1987 • 409 citations

Leucine zipper structure of the protein CRE-BP1 binding to the cyclic AMP response element in brain.

1989 • 396 citations

Multiple cis- and trans-acting elements mediate the transcriptional response to phorbol esters

1987 • 379 citations

Cyclic AMP regulation of the human glycoprotein hormone alpha-subunit gene is mediated by an 18-base-pair element.

1987 • 293 citations

Structural determinants for transcriptional activation by cAMP-responsive DNA elements.

1988 • 258 citations

Identification of a region in the human vasoactive intestinal polypeptide gene responsible for regulation by cyclic AMP.

1987 • 236 citations

Structure and chromosomal localization of the functional intronless human JUN protooncogene.

1988 • 221 citations

Induction of metallothionein and other mRNA species by carcinogens and tumor promoters in primary human skin fibroblasts.

1986 • 215 citations

Cyclic AMP and phorbol ester-stimulated transcription mediated by similar DNA elements that bind distinct proteins.

1988 • 198 citations

Both the basic region and the ‘leucine zipper’ domain of the cyclic AMP response element binding (CREB) protein are essential for transcriptional activation.

1990 • 196 citations

The protein encoded by the human proto-oncogene c-myc.

1984 • 192 citations

A Protein That Binds to a cis-acting Element of Wheat Histone Genes Has a Leucine Zipper Motif

1989 • 174 citations

Metallothionein gene expression is regulated by serum factors and activators of protein kinase C.

1987 • 156 citations

Gene expression and cAMP.

1985 • 153 citations

Distinct Adenosine 3′,5′-Monophosphate and Phorbol Ester-Responsive Signal Transduction Pathways Converge at the Level of Transcriptional Activation by the Interactions of DNA-Binding Proteins

1989 • 151 citations

Adenoviral control regions activated by E1A and the cAMP response element bind to the same factor.

1988 • 120 citations

Transcriptional Regulation of Chorionic Gonadotropinα- andβ-Subunit Gene Expression by 8-Bromo-Adenosine 3′,5′-Monophosphate*

1986 • 83 citations

Purification and characterization of multiple nuclear factors that bind to the TAX-inducible enhancer within the human T-cell leukemia virus type 1 long terminal repeat.

1989 • 81 citations

trans-acting factors interact with a cyclic AMP response element to modulate expression of the human gonadotropin alpha gene.

1987 • 78 citations

Phosphorylation of cellular proteins regulates their binding to the cAMP response element

1989 • 66 citations

DNA-Binding and Dimerization Domains of Adenosine 3′, 5′- Cyclic Monophosphate-Responsive Protein CREB Reside in the Carboxyl-Terminal 66 Amino Acids

1990 • 36 citations

A nuclear factor is required for transactivation of HTLV-I gene expression.

1988 • 25 citations

Identification of Rat Ovarian Nuclear Factors That Interact with the cAMP-inducible Lactate Dehydrogenase A Subunit Promoter

1989 • 22 citations