Clastogenic Effect of the Human T-cell Leukemia Virus Type I Tax Oncoprotein Correlates with Unstabilized DNA Breaks

Human T Cell Leukemia Virus Type 1 Oncoprotein Tax Targets the Human Mitotic Checkpoint Protein MAD1

1998 • 528 citations

Relocalization of Telomeric Ku and SIR Proteins in Response to DNA Strand Breaks in Yeast

1999 • 458 citations

Significance of multiple mutations in cancer

2000 • 441 citations

HTLV-I Trans-Activator Protein, Tax, is a Trans-Repressor of the Human β-Polymerase Ggene

1990 • 329 citations

Aneuploidy vs. gene mutation hypothesis of cancer: Recent study claims mutation but is found to support aneuploidy

2000 • 253 citations

Cancer of the microsatellite mutator phenotype.

1996 • 226 citations

Developmentally programmed healing of chromosomes by telomerase in tetrahymena

1991 • 204 citations

Large deletions result from breakage and healing of P. falciparum chromosomes

1988 • 180 citations

Wag the Tail: Structural Dynamics of Actomyosin

1998 • 140 citations

Disruption of Nucleotide Excision Repair by the Human T-Cell Leukemia Virus Type 1 Tax Protein

1999 • 120 citations

Defective DNA Repair in Cells With Human T-Cell Leukemia/Bovine Leukemia Viruses: Role of tax Gene

1999 • 117 citations

Autonomous replication and addition of telomerelike sequences to DNA microinjected into Paramecium tetraurelia macronuclei.

1988 • 95 citations

HTLV-I and HTLV-II Tax: Differences in Induction of Micronuclei in Cells and Transcriptional Activation of Viral LTRs

1996 • 90 citations

Induction of Micronuclei by HTLV-I Tax: A Cellular Assay for Function

1993 • 89 citations

Identification of healed terminal DNA fragments in linear minichromosomes of Schizosaccharomyces pombe.

1987 • 79 citations

Trans-activator Tax of Human T-Cell Leukemia Virus Type 1 Enhances Mutation Frequency of the Cellular Genome

1999 • 78 citations

Oligonucleotide probes for the analysis of specific repetitive DNA sequences by fluorescence in situ hybridization

1992 • 61 citations

Sensitivity to DNA cross-linking chemotherapeutic agents in mismatch repair-defective cellsin vitro and in xenografts

2000 • 54 citations

Analysis of micronuclei induced by 2-chlorobenzylidene malonitrile (CS) using fluorescence in situ hybridization with telomeric and centromeric DNA probes, and flow cytometry

1993 • 48 citations

In vivo construction of linear vectors based on killer plasmids from Kluyveromyces lactis: selection of a nuclear gene results in attachment of telomeres.

1989 • 47 citations

A Short C-terminal Domain of Yku70p Is Essential for Telomere Maintenance

2000 • 33 citations

Induction of micronuclei by mitomycin C and colchicine in the marine mussel Mytilus galloprovincialis

1990 • 28 citations

Expression status of Tax protein in human T-cell leukemia virus type 1-transformed MT4 cells: recall of MT4 cells distributed by the NIH AIDS Research and Reference Reagent Program

1997 • 19 citations

Identification of kinetochores and DNA synthesis in micronuclei induced by mitomycin C and colchicine in chinese hamster ovary cells

1992 • 11 citations

Urine mutagenicity of petroleum plant workers

1989 • 6 citations