Caveolae Are a Novel Pathway for Membrane-Type 1 Matrix Metalloproteinase Traffic in Human Endothelial Cells

Regulation of Renal Organic Anion Transporter 3 (SLC22A8) Expression and Function by the Integrity of Lipid Raft Domains and their Associated Cytoskeleton

2013 • 2,950 citations

A matrix metalloproteinase expressed on the surface of invasive tumour cells

1994 • 2,561 citations

Loss of Caveolae, Vascular Dysfunction, and Pulmonary Defects in Caveolin-1 Gene-Disrupted Mice

2001 • 1,517 citations

Caveolins, a Family of Scaffolding Proteins for Organizing “Preassembled Signaling Complexes” at the Plasma Membrane

1998 • 1,502 citations

ECM and Cell Surface Proteolysis: Regulating Cellular Ecology

1997 • 1,311 citations

MT1-MMP-Deficient Mice Develop Dwarfism, Osteopenia, Arthritis, and Connective Tissue Disease due to Inadequate Collagen Turnover

1999 • 1,280 citations

Matrix metalloproteinases: they're not just for matrix anymore!

2001 • 1,257 citations

Caveolin-1 Null Mice Are Viable but Show Evidence of Hyperproliferative and Vascular Abnormalities

2001 • 1,144 citations

Caveolins, Liquid-Ordered Domains, and Signal Transduction

1999 • 1,016 citations

Vascular Endothelial Cell Adherens Junction Assembly and Morphogenesis Induced by Sphingosine-1-Phosphate

1999 • 999 citations

Extraction of Cholesterol with Methyl-β-Cyclodextrin Perturbs Formation of Clathrin-coated Endocytic Vesicles

1999 • 970 citations

Rac Downregulates Rho Activity

1999 • 840 citations

Regulated internalization of caveolae.

1994 • 760 citations

Membrane-Type 1 Matrix Metalloproteinase Cleaves Cd44 and Promotes Cell Migration

2001 • 732 citations

A Requirement for Caveolin-1 and Associated Kinase Fyn in Integrin Signaling and Anchorage-Dependent Cell Growth

1998 • 720 citations

Membrane microdomains and caveolae

1999 • 580 citations

Acute cholesterol depletion inhibits clathrin-coated pit budding

1999 • 576 citations

The plasma membrane

1983 • 561 citations

Reduction of caveolin and caveolae in oncogenically transformed cells.

1995 • 505 citations

Rho-family GTPases in cadherin-mediated cell — cell adhesion

2001 • 424 citations

A Role for Caveolin and the Urokinase Receptor in Integrin-mediated Adhesion and Signaling

1999 • 402 citations

Homophilic complex formation of MT1-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion

2001 • 382 citations

Role of GTP Hydrolysis in Fission of Caveolae Directly from Plasma Membranes

1996 • 370 citations

The fibronectin-binding integrins α5β1 and αvβ3 differentially modulate RhoA–GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis

2002 • 322 citations

Identification of Filamin as a Novel Ligand for Caveolin-1: Evidence for the Organization of Caveolin-1–associated Membrane Domains by the Actin Cytoskeleton

2000 • 303 citations

Membrane type I-matrix metalloproteinase (MT1-MMP) is internalised by two different pathways and is recycled to the cell surface

2003 • 254 citations

Regulation of membrane-type matrix metalloproteinase 1 activity by dynamin-mediated endocytosis

2001 • 253 citations

Membrane Type 1-Matrix Metalloproteinase Is Activated during Migration of Human Endothelial Cells and Modulates Endothelial Motility and Matrix Remodeling

2001 • 250 citations

Caveolin cycles between plasma membrane caveolae and the Golgi complex by microtubule-dependent and microtubule-independent steps.

1995 • 243 citations

Integrin Connections Map: To Infinity and Beyond

2002 • 234 citations

Cytoplasmic tail–dependent internalization of membrane-type 1 matrix metalloproteinase is important for its invasion-promoting activity

2001 • 234 citations

The cell surface: the stage for matrix metalloproteinase regulation of migration

2002 • 232 citations

N-cadherin–dependent cell–cell contact regulates Rho GTPases and β-catenin localization in mouse C2C12 myoblasts

2002 • 224 citations

ECM regulates MT1-MMP localization with β1 or αvβ3 integrins at distinct cell compartments modulating its internalization and activity on human endothelial cells

2002 • 211 citations

Caveolin-deficient mice: insights into caveolar function human disease

2001 • 202 citations

Regulation of endocytic traffic by Rho family GTPases

2000 • 198 citations

The urokinase-type plasminogen activator receptor, a GPI-linked protein, is localized in caveolae.

1995 • 196 citations

Caveolin-deficient mice: insights into caveolar function human disease

2001 • 193 citations

Role of Cholesterol in Formation and Function of a Signaling Complex Involving αvβ3, Integrin-Associated Protein (Cd47), and Heterotrimeric G Proteins

1999 • 174 citations

MMP-2 Colocalizes with Caveolae on the Surface of Endothelial Cells

2001 • 171 citations

An Alternative Processing of Integrin αv Subunit in Tumor Cells by Membrane Type-1 Matrix Metalloproteinase

2002 • 152 citations

Endothelial Ca ²⁺ waves preferentially originate at specific loci in caveolin-rich cell edges

1998 • 147 citations

Localization of membrane-type 1 matrix metalloproteinase in caveolae membrane domains

2001 • 145 citations

Front-cell-specific expression of membrane-type 1 matrix metalloproteinase and gelatinase A during cohort migration of colon carcinoma cells induced by hepatocyte growth factor/scatter factor.

2000 • 133 citations

Oligomerization through Hemopexin and Cytoplasmic Domains Regulates the Activity and Turnover of Membrane-type 1 Matrix Metalloproteinase

2002 • 129 citations

Caveolin-1 Binding to Endoplasmic Reticulum Membranes and Entry into the Regulated Secretory Pathway Are Regulated by Serine Phosphorylation

2001 • 122 citations

Cell adhesion and Rho small GTPases

1999 • 105 citations

Localization of RhoA GTPase to Endothelial Caveolae-Enriched Membrane Domains

1998 • 104 citations

Localization of membrane-type 1 matrix metalloproteinase in caveolae membrane domains

2001 • 103 citations

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