Pre- and postsynaptic changes mediated by two second messengers contribute to expression of aplysia long-term heterosynaptic inhibition

Selective stabilisation of developing synapses as a mechanism for the specification of neuronal networks

1976 • 1,444 citations

Developmental mechanisms that generate precise patterns of neuronal connectivity

1993 • 1,435 citations

A Requirement for the Intercellular Messenger Nitric Oxide in Long-Term Potentiation

1991 • 1,136 citations

Structure of a Molluscan Cardioexcitatory Neuropeptide

1977 • 1,055 citations

Tests of the roles of two diffusible substances in long-term potentiation: evidence for nitric oxide as a possible early retrograde messenger.

1991 • 1,016 citations

Endogenous nitric oxide release required for long-term synaptic depression in the cerebellum

1991 • 875 citations

The Neural Cell Adhesion Molecule (NCAM) as a Regulator of Cell-Cell Interactions

1988 • 790 citations

A Critical Period for Macromolecular Synthesis in Long-Term Heterosynaptic Facilitation in Aplysia

1986 • 767 citations

Patterned Activity, Synaptic Convergence, and the NMDA Receptor in Developing Visual Pathways

1990 • 765 citations

Injection of the cAMP-responsive element into the nucleus of Aplysia sensory neurons blocks long-term facilitation

1990 • 741 citations

A Physiological Mechanism for Hebb's Postulate of Learning

1973 • 711 citations

Lipoxygenase metabolites of arachidonic acid as second messengers for presynaptic inhibition of Aplysia sensory cells

1987 • 640 citations

Hebbian Synapses: Biophysical Mechanisms and Algorithms

1990 • 551 citations

Spatially Resolved Dynamics of cAMP and Protein Kinase A Subunits in Aplysia Sensory Neurons

1993 • 549 citations

Synaptic Facilitation and Behavioral Sensitization in Aplysia : Possible Role of Serotonin and Cyclic AMP

1976 • 515 citations

Adhesion molecules and the hierarchy of neural development

1988 • 431 citations

Morphological Basis of Long-Term Habituation and Sensitization in Aplysia

1983 • 420 citations

Intracellular injection of t he catalytic subunit of cyclic AMP-dependent protein kinase simulates facilitation of transmitter release underlying behavioral sensitization in Aplysia.

1980 • 380 citations

Modulation of an NCAM-Related Adhesion Molecule with Long-Term Synaptic Plasticity in Aplysia

1992 • 377 citations

Synaptic transmission: A bidirectional and self-modifiable form of cell-cell communication

1993 • 371 citations

Asymmetric modulation of cytosolic cAMP activity induces growth cone turning

1992 • 355 citations

Activation of cAMP-Responsive genes by stimuli that produce long-term facilitation in aplysia sensory neurons

1993 • 353 citations

Polysialic acid as a regulator of intramuscular nerve branching during embryonic development

1990 • 319 citations

Serotonin-Mediated Endocytosis of apCAM: an Early Step of Learning-Related Synaptic Growth in Aplysia

1992 • 313 citations

Long-term memory in Aplysia modulates the total number of varicosities of single identified sensory neurons.

1988 • 291 citations

In vivo visualization of pre- and postsynaptic changes during synapse elimination in reinnervated mouse muscle

1989 • 290 citations

Neurite regeneration by Aplysia neurons in dissociated cell culture: modulation by Aplysia hemolymph and the presence of the initial axonal segment

1983 • 281 citations

cAMP Evokes Long-Term Facilitation in Aplysia Sensory Neurons That Requires New Protein Synthesis

1988 • 265 citations

Two endogenous neuropeptides modulate the gill and siphon withdrawal reflex in Aplysia by presynaptic facilitation involving cAMP-dependent closure of a serotonin-sensitive potassium channel.

1984 • 261 citations

Roles of PKA and PKC in facilitation of evoked and spontaneous transmitter release at depressed and nondepressed synapses in aplysia sensory neurons

1992 • 253 citations

A molecular mechanism for long-term sensitization in Aplysia

1987 • 234 citations

Target-Dependent Structural Changes Accompanying Long-Term Synaptic Facilitation in Aplysia Neurons

1990 • 230 citations

Polysialic acid influences specific pathfinding by avian motoneurons

1992 • 229 citations

Facilitatory transmitter causes a selective and prolonged increase in adenosine 3':5'-monophosphate in sensory neurons mediating the gill and siphon withdrawal reflex in Aplysia

1982 • 215 citations

Aplysia neurons express a gene encoding multiple FMRFamide neuropeptides

1985 • 189 citations

Inhibitors of protein and RNA synthesis block structural changes that accompany long-term heterosynaptic plasticity in Aplysia

1992 • 181 citations

Cellular Analysis of Long-Term Habituation of the Gill-Withdrawal Reflex of Aplysia californica

1978 • 177 citations

Cyclic AMP induces changes in distribution and transport of organelles within growth cones of Aplysia bag cell neurons

1987 • 177 citations

Synaptic plasticity in vitro: cell culture of identified Aplysia neurons mediating short-term habituation and sensitization

1986 • 174 citations

Second messengers involved in the two processes of presynaptic facilitation that contribute to sensitization and dishabituation in Aplysia sensory neurons.

1990 • 173 citations

Long-Term Sensitization in Aplysia : Biophysical Correlates in Tail Sensory Neurons

1987 • 171 citations

Neuronal inhibition by the peptide FMRFamide involves opening of S K+ channels

1987 • 170 citations

Neurite outgrowth in individual neurons of a neuronal population is differentially regulated by calcium and cyclic AMP

1988 • 164 citations

Transition of localization of the N-Myc protein from nucleus to cytoplasm in differentiating neurons

1993 • 137 citations

Direct modulation of Aplysia S-K+ channels by a 12-lipoxygenase metabolite of arachidonic acid

1989 • 135 citations

Intracellular Injection of cAMP Induces a Long-Term Reduction of Neuronal K ⁺ Currents

1988 • 134 citations

Tail shock produces inhibition as well as sensitization of the siphon-withdrawal reflex of Aplysia: possible behavioral role for presynaptic inhibition mediated by the peptide Phe-Met-Arg-Phe-NH2.

1987 • 133 citations

Hebbian Depression of Isolated Neuromuscular Synapses in Vitro

1992 • 128 citations

Facilitatory and inhibitory transmitters modulate spontaneous transmitter release at cultured Aplysia sensorimotor synapses.

1990 • 124 citations

The Aplysia FMRFamide Gene Encodes Sequences Related to Mammalian Brain Peptides

1986 • 123 citations

Serotonin produces long-term changes in the excitability of Aplysia sensory neurons in culture that depend on new protein synthesis

1987 • 123 citations

Long-term heterosynaptic inhibition in Aplysia

1988 • 120 citations

Long-Term Facilitation in Aplysia Involves Increase in Transmitter Release

1988 • 119 citations

Facilitatory transmitters and cAMP can modulate accommodation as well as transmitter release in Aplysia sensory neurons: Evidence for parallel processing in a single cell

1986 • 119 citations

Synthesis, location, and lateral mobility of fluorescently labeled ubiquinone 10 in mitochondrial and artificial membranes

1989 • 118 citations

A neuromodulator of synaptic transmission acts on the secretory apparatus as well as on ion channels

1989 • 117 citations

Membrane responses and changes in cAMP levels in Aplysia sensory neurons produced by serotonin, tryptamine, FMRFamide and small cardioactive peptideB (SCPB)

1985 • 116 citations

Expression of diverse neuropeptide cotransmitters by identified motor neurons in Aplysia

1991 • 108 citations

Identified target motor neuron regulates neurite outgrowth and synapse formation of aplysia sensory neurons in vitro

1989 • 106 citations

Peptide‐immunocytochemistry of neurosecretory cells in the brain and retrocerebral complex of the sphinx moth Manduca sexta

1991 • 102 citations

Differential effects of cAMP and serotonin on membrane current, action-potential duration, and excitability in somata of pleural sensory neurons of Aplysia

1990 • 102 citations

The neuropeptide FMRF-amide decreases both the Ca2+ conductance and a cyclic 3',5'-adenosine monophosphate-dependent K+ conductance in identified molluscan neurons

1985 • 89 citations

Two FMRFamide-like peptides from the free-living nematode Panagrellus redivivus

1992 • 85 citations

Regulation of heartbeat in Lymnaea by motoneurons containing FMRFamide-like peptides

1990 • 84 citations

Suppression of calcium current by an endogenous neuropeptide in neurones of Aplysia californica.

1987 • 81 citations

Differential synapse formation and neurite outgrowth at two branches of the metacerebral cell of Aplysia in dissociated cell culture

1985 • 80 citations

5-HT and cAMP induce the formation of coated pits and vesicles and increase the expression of clathrin light chain in sensory neurons of aplysia

1993 • 76 citations

cAMP induces long-term morphological changes in sensory neurons ofAplysia

1991 • 75 citations

Modulatory effects of serotonin, FMRFamide, and myomodulin on the duration of action potentials, excitability, and membrane currents in tail sensory neurons of Aplysia

1991 • 74 citations

cAMP and arachidonic acid simulate long-term structural and functional changes produced by neurotransmitters in aplysia sensory neurons

1993 • 70 citations

Facilitatory and inhibitory transmitters modulate calcium influx during action potentials in Aplysia sensory neurons

1990 • 70 citations

FMRFamide peptides in Helisoma: identification and physiological actions at a peripheral synapse

1988 • 63 citations

Long-term Facilitation in Aplysia: Persistent Phosphorylation and Structural Changes

1990 • 59 citations

Neurite guidance molecules

1989 • 57 citations

Synaptic target contact enhances presynaptic calcium influx by activating CAMP-dependent protein kinase during synaptogenesis

1993 • 57 citations

Target-dependent structural changes in sensory neurons of aplysia accompany long-term heterosynaptic inhibition

1991 • 56 citations

Differential effects of serotonin, FMRFamide, and small cardioactive peptide on multiple, distributed processes modulating sensorimotor synaptic transmission in Aplysia

1992 • 55 citations

The biology of the FMRFamide-series of peptides in molluscs with special reference to Helix

1989 • 53 citations

Retrograde modulation at developing neuromuscular synapses: Involvement of G protein and arachidonic acid cascade

1992 • 52 citations

Selective short- and long-term effects of serotonin, small cardioactive peptide, and tetanic stimulation on sensorimotor synapses of Aplysia in culture

1990 • 51 citations

Neuron-specific membrane glycoproteins promoting neurite fasciculation in Aplysia californica.

1990 • 50 citations

Identified FMRFamide-immunoreactive neuron LPL16 in the left pleural ganglion of Aplysia produces presynaptic inhibition of siphon sensory neurons

1992 • 45 citations

Decrease in growth cone-neurite fasciculation by sensory or motor cells in vitro accompanies downregulation of Aplysia cell adhesion molecules by neurotransmitters

1994 • 44 citations

Pathway recognition by neuronal growth cones: genetic analysis of neural cell adhesion molecules in Drosophila

1992 • 41 citations

Aminergic and Peptidergic Modulation of Motor Function at an Identified Neuromuscular Junction in Helisoma

1989 • 40 citations

FMRFamide modulation of secretory machinery underlying presynaptic inhibition of synaptic transmission requires a pertussis toxin- sensitive G-protein

1991 • 40 citations

The peptide FMRFamide activates a divalent cation‐conducting channel in heart muscle cells of the snail Lymnaea stagnalis.

1991 • 36 citations

Small cardioactive peptide-like immunoreactivity and its colocalization with FMRFamide-like immunoreactivity in the central nervous system of the leech Hirudo medicinalis

1989 • 36 citations

Activity-Dependent Enhancement of Presynaptic Inhibition in Aplysia Sensory Neurons

1989 • 31 citations

The localization of FMRFamide in the nervous and somatic tissues of Nereis virens and its effects upon the isolated esophagus

1992 • 27 citations

Modulation of a subthreshold calcium current by the neuropeptide FMRFamide in Aplysia neuron R15

1988 • 23 citations

The neuropeptide FMRFa both inhibits and enhances the Ca2+ current in dissociated Helix neurons via independent mechanisms

1991 • 23 citations

Humoral factors released during trauma ofAplysia body wall

1989 • 22 citations

FMRFamide effects on membrane properties of heart cells isolated from the leech, Hirudo medicinalis

1992 • 21 citations

Inhibitory modulation by FMRFamide of the voltage‐gated sodium current in identified neurones in Lymnaea stagnalis.

1991 • 19 citations

A lipoxygenase pathway of arachidonic acid metabolism mediates FMRFamide activation of a potassium current in an identified neuron of Helisoma

1992 • 17 citations

The cyclic GMP‐induced inward current in neuron R14 of Aplysia californica: Similarity to a FMRFamide‐induced inward current

1989 • 17 citations

Humoral factors released during trauma ofAplysia body wall

1989 • 17 citations

Dopamine and FMRFamide act directly on isolated gill muscle fibers in culture

1990 • 11 citations