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The Neuroendocrinology of Mood Disorders

Data up to Jan 2025

Published2009
Citations11
References198

Total Citations Per Year

Abstract

References (198)

Deep Brain Stimulation for Treatment-Resistant Depression

2005 • 3,877 citations

A Neurotrophic Model for Stress-Related Mood Disorders

2006 • 3,154 citations

Brain Corticosteroid Receptor Balance in Health and Disease*

1998 • 2,442 citations

The Corticosteroid Receptor Hypothesis of Depression

2000 • 2,126 citations

Psychopharmacology: The Fourth Generation of Progress

1995 • 1,676 citations

Neurocircuitry of Mood Disorders

2009 • 1,508 citations

Neuroimaging studies of mood disorders

2000 • 1,303 citations

Williams' Textbook of Endocrinology.

1991 • 1,248 citations

Biological, Physiological, Pathophysiological, and Pharmacological Aspects of Ghrelin

2004 • 1,186 citations

Fundamental Neuroscience

2000 • 1,181 citations

The adrenal cortex.

1998 • 1,134 citations

Clinical and Biochemical Manifestations of Depression

1988 • 1,052 citations

The Decline of Androgen Levels in Elderly Men and Its Clinical and Therapeutic Implications

2005 • 1,051 citations

Neuropsychopharmacology: The Fifth Generation of Progress

2002 • 990 citations

Dopamine as a Prolactin (PRL) Inhibitor

2001 • 906 citations

Altered Gene Expression of Brain-Derived Neurotrophic Factor and Receptor Tyrosine Kinase B in Postmortem Brain of Suicide Subjects

2003 • 831 citations

Antidepressants and Hypothalamic-Pituitary-Adrenocortical Regulation

1996 • 829 citations

Responses to Corticotropin-Releasing Hormone in the Hypercortisolism of Depression and Cushing's Disease

1986 • 773 citations

The Diagnosis and Differential Diagnosis of Cushing’s Syndrome and Pseudo-Cushing’s States

1998 • 746 citations

Interaction between BDNF and Serotonin: Role in Mood Disorders

2007 • 726 citations

Effects of the high-affinity corticotropin-releasing hormone receptor 1 antagonist R121919 in major depression: the first 20 patients treated

2000 • 698 citations

The combined dexamethasone/CRH test: A refined laboratory test for psychiatric disorders

1994 • 663 citations

Increased Numbers of Corticotropin-Releasing Hormone Expressing Neurons in the Hypothalamic Paraventricular Nucleus of Depressed Patients

1994 • 657 citations

Neurotransmitter receptors on microglia

2007 • 602 citations

Pubertal changes in hormone levels and depression in girls

1999 • 566 citations

Pronounced and sustained central hypernoradrenergic function in major depression with melancholic features: Relation to hypercortisolism and corticotropin-releasing hormone

2000 • 559 citations

Estrogen and Cognitive Functioning in Women

2003 • 531 citations

Estrogen Regulation of Growth Hormone Action

2004 • 499 citations

Brain-Derived Neurotrophic Factor Conditional Knockouts Show Gender Differences in Depression-Related Behaviors

2006 • 493 citations

Molecular Basis of Thyroid Hormone-Dependent Brain Development*

1997 • 490 citations

Glucose metabolism in the amygdala in depression: Relationship to diagnostic subtype and plasma cortisol levels

2002 • 446 citations

A Review of Postpartum Psychosis

2006 • 417 citations

Oral administration of a corticotropin-releasing hormone receptor antagonist significantly attenuates behavioral, neuroendocrine, and autonomic responses to stress in primates

2000 • 395 citations

Dysregulation in the Suicide Brain: mRNA Expression of Corticotropin-Releasing Hormone Receptors and GABAAReceptor Subunits in Frontal Cortical Brain Region

2004 • 378 citations

Do Corticosteroids Damage the Brain?

2006 • 367 citations

Effect of treatment on serum brain–derived neurotrophic factor levels in depressed patients

2005 • 365 citations

Dopamine and depression

1993 • 349 citations

Life events, first depression onset and the serotonin transporter gene

2006 • 316 citations

PSYCHIATRIC SEQUELÆ OF CHRONIC EXPOSURE TO ORGANOPHOSPHORUS INSECTICIDES

1961 • 314 citations

Neuroendocrine Control of Prolactin Secretion

1983 • 305 citations

Elevated Frequency of Diabetes Mellitus in Hospitalized Manic-Depressive Patients

1999 • 304 citations

Amygdaloid Corticotropin‐Releasing Factor Targets Locus Coeruleus Dendrites: Substrate for the Co‐ordination of Emotional and Cognitive Limbs of the Stress Response

1998 • 303 citations

Behavioral Effects of Chronic Fluoxetine in BALB/cJ Mice Do Not Require Adult Hippocampal Neurogenesis or the Serotonin 1A Receptor

2007 • 303 citations

Serotonin and the regulation of hypothalamic-pituitary-adrenal axis function

1996 • 303 citations

Pathophysiology of hypercortisolism in depression

2007 • 302 citations

Reduced Brain Norepinephrine and Dopamine Release in Treatment-Refractory Depressive Illness

2000 • 291 citations

The Dexamethasone Suppression Test and Suicide Prediction

2001 • 288 citations

Corticotropin-Releasing Hormone in Humans*

1992 • 283 citations

Neuroendocrine Aspects of Primary Endogenous Depression

1987 • 278 citations

Estrogen, serotonin, and mood disturbance: where is the therapeutic bridge?

1998 • 278 citations

SEX STEROID CONTROL OF MOOD, MENTAL STATE AND MEMORY

1998 • 240 citations

Prophylactic estrogen in recurrent postpartum affective disorder

1995 • 238 citations

Pituitary Size in Depression*

1991 • 237 citations

Prediction of Medium-Term Outcome by Cortisol Response to the Combined Dexamethasone-CRH Test in Patients With Remitted Depression

1999 • 234 citations

Elevated Serotonin Transporter Binding in Major Depressive Disorder Assessed Using Positron Emission Tomography and [11C]DASB; Comparison with Bipolar Disorder

2007 • 214 citations

Subclinical hypothyroidism: neurobehavioral features and beneficial effect of l-thyroxine treatment

1993 • 210 citations

Cerebrospinal fluid and plasma free cortisol concentrations in depression

1976 • 210 citations

Adrenal Gland Volume in Major Depression

1995 • 209 citations

Treatment of Depression With Antiglucocorticoid Drugs

1999 • 208 citations

Brain-derived neurotrophic factor (BDNF) changes in the serum of depressed women

2006 • 207 citations

Plasma and serum brain-derived neurotrophic factor (BDNF) in depressed patients during 1 year of antidepressant treatments

2007 • 205 citations

Monoamine Transporter Gene Polymorphisms and Antidepressant Response in Koreans With Late-Life Depression

2006 • 202 citations

Mineralocorticoid Receptor Function in Major Depression

2003 • 202 citations

Twenty-Four-Hour ACTH and Cortisol Pulsatility in Depressed Women

2001 • 191 citations

The validity of psychiatric diagnosis

1990 • 191 citations

Bed with bedpan.

1958 • 189 citations

Growth Hormone Releasing Peptides

1996 • 188 citations

The glucocorticoid receptor: part of the solution or part of the problem?

2006 • 185 citations

Sex Specific Associations between Common Glucocorticoid Receptor Gene Variants and Hypothalamus-Pituitary-Adrenal Axis Responses to Psychosocial Stress

2007 • 184 citations

Metyrapone as Additive Treatment in Major Depression

2004 • 177 citations

Increased Evening Activation of the Hypothalamic-Pituitary-Adrenal Axis in Depressed Patients

1994 • 168 citations

Long‐Term Antidepressant Treatment Reduces Behavioural Deficits in Transgenic Mice with Impaired Glucocorticoid Receptor Function

1995 • 168 citations

HPA axis dysfunction in unmedicated major depressive disorder and its normalization by pharmacotherapy correlates with alteration of neural activity in prefrontal cortex and limbic/paralimbic regions

2007 • 164 citations

The Scope of Psychoendocrine Research

1968 • 162 citations

5-HT1A receptor responsivity in unipolar depression Evaluation of ipsapirone-induced ACTH and cortisol secretion in patients and controls

1990 • 161 citations

Treatment of Refractory Depression with High-Dose Thyroxine

1998 • 161 citations

Chapter 21 The role of corticotropin-releasing hormone in the pathogenesis of Cushing's disease, anorexia nervosa, alcoholism, affective disorders and dementia

1992 • 160 citations

Risk for Premenstrual Dysphoric Disorder Is Associated with Genetic Variation in ESR1, the Estrogen Receptor Alpha Gene

2007 • 155 citations

Functional relevance of neurotransmitter receptor heteromers in the central nervous system

2007 • 154 citations

Increased Pituitary Volume in Antipsychotic-Free and Antipsychotic-Treated Patients of the Æsop First-Onset Psychosis Study

2005 • 152 citations

Corticotropin-Releasing Hormone, Arginine Vasopressin, Gastrin-Releasing Peptide, and Neuromedin B Alterations in Stress-Relevant Brain Regions of Suicides and Control Subjects

2005 • 151 citations

In vivo assessment of pituitary volume with magnetic resonance imaging and systematic stereology: Relationship to dexamethasone suppression test results in patients

1992 • 150 citations

Cholecystokinin and endogenous opioid peptides: Interactive influence on pain, cognition, and emotion

2005 • 149 citations

Dexamethasone suppression test: a review of contemporary confusion.

1985 • 139 citations

Decreased pituitary volume in patients with bipolar disorder

2001 • 139 citations

Circadian Uses of Melatonin in Humans

2006 • 135 citations

Elevated Concentrations of CRF in the Locus Coeruleus of Depressed Subjects

2003 • 135 citations

Antiglucocorticoid therapies in major depression: A review

1997 • 134 citations

MOOD DISORDERS AND MENOPAUSE

1997 • 131 citations

Brain Serotonin Transporter Binding in Depressed Patients With Bipolar Disorder Using Positron Emission Tomography

2007 • 130 citations

Neurobiology of Serotonin in Depression and Suicidea

1997 • 127 citations

Adrenal Cortical Activity in Pathological Emotional States : A Review

1966 • 126 citations

Human corticotropin-releasing hormone in depression—correlation with thyrotropin secretion following thyrotropin-releasing hormone

1986 • 125 citations

A review of the efficacy of serotonergic and noradrenergic reuptake inhibitors for treatment of major depression

1999 • 124 citations

Neuroendocrine Aspects of Primary Endogenous Depression

1992 • 124 citations

The Involvement of the Vasopressin System in Stress-Related Disorders

2006 • 124 citations

Gonadal Steroids in the Treatment of Mood Disorders

1999 • 123 citations

Adrenal gland volume in major depression: Relationship to basal and stimulated pituitary-adrenal cortical axis function

1996 • 121 citations

Regional Cerebral Glucose Metabolic Abnormalities in Bipolar II Depression

2006 • 118 citations

Modulation of binding sites for corticotropin-releasing hormone by chronic psychosocial stress

1995 • 116 citations

Gene Expression Profiling in Postmortem Prefrontal Cortex of Major Depressive Disorder

2007 • 115 citations

The role of Corticotropin Releasing Factor in Depressive Illness: a Critical Review

1998 • 114 citations

Enhanced Adrenal Sensitivity to Exogenous Cosyntropin (ACTH α1-24) Stimulation in Major Depression

1987 • 113 citations

Melatonin Sensitivity to Dim White Light in Affective Disorders

1999 • 113 citations

Inhibition by Somatostatin of Basal Levels of Serum Thyrotropin (TSH) in Normal Men

1975 • 112 citations

Recent Advances with the CRF1 Receptor: Design of Small Molecule Inhibitors, Receptor Subtypes and Clinical Indications

1999 • 110 citations

Anatomy of melancholia: focus on hypothalamic–pituitary–adrenal axis overactivity and the role of vasopressin

2005 • 106 citations

Long-term fluoxetine treatment decreases 5-HT1A receptor responsivity in obsessive-compulsive disorder

1991 • 105 citations

Low cerebrospinal fluid corticotropin-releasing hormone concentrations in eucortisolemic depression

1997 • 104 citations

Recent advances with the CRF1 receptor: design of small molecule inhibitors, receptor subtypes and clinical indications.

1999 • 103 citations

The Effects of Antidepressants on the Hypothalamic-Pituitary-Adrenal Axis

2006 • 101 citations

Pituitary and Adrenocortical Responses to the Ovine Corticotropin Releasing Hormone in Depressed Patients and Healthy Volunteers

1987 • 97 citations

Long‐Term Treatment with Antidepressants Increases Glucocorticoid Receptor Binding and Gene Expression in Cultured Rat Hippocampal Neurones

1999 • 94 citations

DST non-suppression predicts suicide after attempted suicide

2007 • 93 citations

Neurosteroids, neuroactive steroids, and symptoms of affective disorders

2006 • 90 citations

Pathophysiology of “cholinoceptor supersensitivity” in affective disorders

1986 • 90 citations

Low Cerebrospinal Fluid Transthyretin Levels in Depression: Correlations with Suicidal Ideation and Low Serotonin Function

2006 • 89 citations

Treatment response in melancholia

2007 • 86 citations

Motivation and Reward

2004 • 86 citations

Blunting of ACTH response to human CRH in depressed patients is avoided by metyrapone pretreatment

1988 • 84 citations

MRI study of the pituitary gland in adolescent depression

2003 • 84 citations

Do Substance P and the NK1 Receptor have a Role in Depression and Anxiety?

2005 • 83 citations

Growth hormone secretion: The role of glucocorticoids

1994 • 83 citations

Effect of growth hormone (GH)-releasing hormone (GHRH), atropine, pyridostigmine, or hypoglycemia on GHRP-6-induced GH secretion in man.

1993 • 81 citations

Effects of receptor blockers (methysergide, propranolol, phentolamine, yohimbine and prazosin) on desimipramine-induced pituitary hormone stimulation in humans—II. Prolactin

1986 • 80 citations

Effects of antidepressant treatment and of gender on serum leptin levels in patients with major depression

2005 • 79 citations

Cerebrospinal fluid corticotropin-releasing hormone, vasopressin, and oxytocin concentrations in treated patients with major depression and controls

1995 • 77 citations

SECTION II. SYNAPTIC ROLE OF TRH: Distribution of TRH-like Immunoreactivity with Special Reference to Coexistence with Other Neuroactive Compounds

1989 • 75 citations

5-HT1A receptor function in depression: effect of chronic amitriptyline treatment

1990 • 74 citations

Insulin sensitivity, proinflammatory markers and adiponectin in young males with different subtypes of depressive disorder

2007 • 71 citations

5-HTT Binding in Recovered Depressed Patients and Healthy Volunteers: A Positron Emission Tomography Study With [ 11 C]DASB

2007 • 71 citations

Supraphysiological Doses of L-Thyroxine in the Maintenance Treatment of Prophylaxis-Resistant Affective Disorders

2002 • 70 citations

Desmopressin Normalizes the Blunted Adrenocorticotropin Response to Corticotropin-Releasing Hormone in Melancholic Depression: Evidence of Enhanced Vasopressinergic Responsivity

1999 • 66 citations

Behavioral profiling of NPY in aggression and neuropsychiatric diseases

2006 • 64 citations

Hyperactivity of the hypothalamic–pituitary–adrenal axis and mortality in major depressive disorder

2005 • 64 citations

The influence of estrogen on monoamine oxidase activity.

1997 • 64 citations

Serum thyrotropin in hospitalized psychiatric patients: Evidence for hyperthyrotropinemia as measured by an ultrasensitive thyrotropin assay

1990 • 63 citations

Neuroendocrine aspects of primary endogenous depression. V. Serum prolactin measures in patients and matched control subjects.

1989 • 63 citations

Clinical and Subclinical Hypothyroidism in Patients with Chronic and Treatment-Resistant Depression

1996 • 62 citations

Pituitary Volume in Treatment-Naïve Pediatric Major Depressive Disorder

2006 • 61 citations

SECTION II. SYNAPTIC ROLE OF TRH: Distribution of TRH-like Immunoreactivity with Special Reference to Coexistence with Other Neuroactive Compounds

1989 • 60 citations

Tachykinins and Neuropsychiatric Disorders

2006 • 59 citations

Hypothalamo–pituitary–adrenal cortical responses to low-dose physostigmine and arginine vasopressin administration: sex differences between major depressives and matched control subjects

1999 • 57 citations

PSYCHONEUROENDOCRINOLOGY OF DEPRESSION

1998 • 55 citations

Corticotropin Secretory Dynamics in Humans under Low Glucocorticoid Feedback

2001 • 54 citations

Further neuroendocrine evidence of enhanced vasopressin V3 receptor responses in melancholic depression

2004 • 53 citations

Cerebrospinal Fluid Corticotropin-Releasing Hormone in Healthy Humans: Effects of Yohimbine and Naloxone

2000 • 52 citations

Neuroendocrine aspects of primary endogenous depression—IV. Pituitary-thyroid axis activity in patients and matched control subjects

1987 • 51 citations

Effect of receptor blockers (methysergide, propranolol, phentolamine, yohimbine and prazosin) on desimipramine-induced pituitary hormone stimulation in humans—I. Growth hormone

1986 • 50 citations

Cholecystokinin in CSF from depressed patients: possible relations to severity of depression and suicidal behaviour

1998 • 50 citations

Serial dexamethasone suppression tests among rapidly cycling bipolar patients.

1982 • 49 citations

DOMPERIDONE: A NOVEL AGENT FOR THE INVESTIGATION OF ANTERIOR PITUITARY FUNCTION AND CONTROL IN MAN

1980 • 47 citations

Dopamine stimulates release of thyrotrophin-releasing hormone from perfused intact rat hypothalamus via hypothalamic D2-receptors

1987 • 43 citations

DST abnormality as a predictor of course in major depression

1990 • 41 citations

Effect of Metyrapone on the Pituitary-Adrenal Axis in Depression Relation to Dexamethasone Suppressor Status

1992 • 39 citations

Thyrotropin-releasing hormone gene expression in the human hypothalamus

1996 • 39 citations

Pyridostigmine-induced growth hormone responses in healthy and depressed subjects: evidence for cholinergic supersensitivity in depression

1992 • 38 citations

Tryptophan depletion in recently manic patients treated with lithium

1998 • 38 citations

Neurotransmitter control of hypothalamic-pituitary-thyroid functions in rats

1981 • 37 citations

The effect of naloxone on adrenocorticotropin and cortisol release: evidence for a reduced response in depression

1999 • 36 citations

A Comparison of Adrenal Cortical Function in Patients with Depressive Illness and Cushing’s Disease

1986 • 34 citations

Emotions in Health and Illness Applications to Clinical Practice

1982 • 34 citations

Opioid Regulation of Hypothalamic-Pituitary-Adrenal Function in Depression

1985 • 33 citations

Effects of electroconvulsive therapy on plasma vasopressin and oxytocin

1998 • 33 citations

Normative hypogonadism and depression: does ‘andropause’ exist?

2006 • 29 citations

The pitfalls of serotonin precursors as challengers in hormonal probes of central serotonin activity.

1986 • 28 citations

Neurosteroids

2007 • 28 citations

Exaggerated TSH Responses to TRH in Depressed Patients With "Normal" Baseline TSH

1997 • 27 citations

The Pharmacogenetics of Major Depression: Past, Present, and Future

2007 • 27 citations

Inhibition of thyroxine 5′-deiodination type II in cultured human placental cells by cortisol, insulin, 3′,5′-cyclic adenosine monophosphate, and butyrate

1988 • 26 citations

The dexamethasone suppression test and treatment outcome in elderly depressed patients participating in a placebo-controlled multicenter trial involving moclobemide and nortriptyline

1997 • 25 citations

Effect of fluoxetine on dexamethasone-induced growth hormone release in depression: a double-blind, placebo-controlled study

1995 • 25 citations

Neuroendocrine aspects of primary endogenous depression X: Serum growth hormone measures in patients and matched control subjects

1990 • 24 citations

A review of GHRH stimulation test in psychiatry

1994 • 23 citations

Lack of relapse with tryptophan depletion following successful treatment with ECT

1997 • 23 citations

Occurrence of galanin-like immunoreactivity in growth hormone-releasing factor (GRF)-containing neurons of the monkey (Macaca fascicularis) infundibular nucleus and median eminence

1990 • 21 citations

Noradrenaline (Norepinephrine) and Depression

1999 • 20 citations

Suppression of melatonin secretion by bright light in seasonal affective disorder

1997 • 20 citations

Neuroendocrine and Other Studies of the Mechanism of Antidepressant Action of Desipramine

2007 • 18 citations

Effect of fluoxetine on noradrenergic mediated growth hormone release: A double blind, placebo-controlled study

1991 • 18 citations

Nocturnal Prolactin Secretion in Depression

1985 • 18 citations

Single nucleotide polymorphism analysis of corticotropin-releasing factor-binding protein gene in recurrent major depressive disorder

2007 • 17 citations

Abnormal responsiveness of growth hormone to human corticotropin-releasing hormone in major depressive disorder

1988 • 17 citations

Association of GABAA receptor subunit genes with childhood absence epilepsy

1997 • 17 citations

Effects of neurotensin on the pituitary-adrenocortical axis of intact and dexamethasone-suppressed rats

1991 • 17 citations

Adrenal cortical responses to low- and high-dose ACTH1–24 administration in major depressives vs. matched controls

2006 • 17 citations

Growth hormone responses to low-dose physostigmine administration: functional sex differences (sexual diergism) between major depressives and matched controls

2003 • 15 citations

The Neuroendocrinology of Affective Disorders

2002 • 15 citations

Plasmatic vasopressin neurophysin in depression: Basic levels and relations with HPA axis

1990 • 14 citations

Anticonvulsants in Bipolar Disorder

2005 • 13 citations

EFFECT OF MORPHINE ON CORTISOL AND PROLACTIN SECRETION IN ANOREXIA NERVOSA AND DEPRESSION

1989 • 11 citations

Pituitary-adrenal axis response to arginine vasopressin in patients with major depression

1993 • 9 citations

Sequence of pituitary–adrenal cortical hormone responses to low-dose physostigmine administration in young adult women and men

2006 • 8 citations

Hypothalamic–Pituitary–Thyroid Axis

2009 • 7 citations

Major affective disorders: Prospective clinical course during a 5- to 7-year follow-up in relation to neuroendocrine function tests

1994 • 3 citations

Hypothalamic-Pituitary-Thyroid Axis

2002 • 3 citations

Creatine Kinase Elevation Associated With Bipolar Disorder and Ephedrine Abuse

2007 • 1 citations

Deleted Work

1955 • 0 citations

Cited By (0)

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