Risk for Premenstrual Dysphoric Disorder Is Associated with Genetic Variation in ESR1, the Estrogen Receptor Alpha Gene

Functional Analysis of Genetic Variation in Catechol-O-Methyltransferase (COMT): Effects on mRNA, Protein, and Enzyme Activity in Postmortem Human Brain

2004 • 1,637 citations

Estrogen Actions in the Central Nervous System¹

1999 • 1,381 citations

Moderation of the Effect of Adolescent-Onset Cannabis Use on Adult Psychosis by a Functional Polymorphism in the Catechol-O-Methyltransferase Gene: Longitudinal Evidence of a Gene X Environment Interaction

2005 • 1,332 citations

Cell Membrane and Nuclear Estrogen Receptors (ERs) Originate from a Single Transcript: Studies of ERα and ERβ Expressed in Chinese Hamster Ovary Cells

1999 • 1,046 citations

Environmental programming of stress responses through DNA methylation: life at the interface between a dynamic environment and a fixed genome

2005 • 898 citations

The CAG repeat within the androgen receptor gene and its relationship to prostate cancer

1997 • 890 citations

Cloning of the human estrogen receptor cDNA.

1985 • 720 citations

Differential Behavioral Effects of Gonadal Steroids in Women with and in Those without Premenstrual Syndrome

1998 • 709 citations

The prevalence, impairment, impact, and burden of premenstrual dysphoric disorder (PMS/PMDD)

2003 • 693 citations

Catechol-o-Methyltransferase, Cognition, and Psychosis: Val158Met and Beyond

2006 • 667 citations

Estrogen Actions in the Central Nervous System

1999 • 641 citations

Polymorphism in serotonin transporter gene associated with susceptibility to major depression

1996 • 534 citations

The Complete Primary Structure of Human Estrogen Receptor β (hERβ) and Its Heterodimerization with ER αin Vivoandin Vitro

1998 • 510 citations

Estrogen–serotonin interactions: implications for affective regulation

1998 • 497 citations

Persistent changes in corticotropin-releasing factor neuronal systems induced by maternal deprivation.

1996 • 493 citations

Midbrain dopamine and prefrontal function in humans: interaction and modulation by COMT genotype

2005 • 431 citations

ERs Associate with and Regulate the Production of Caveolin: Implications for Signaling and Cellular Actions

2002 • 380 citations

The effects of neonatal handling on the development of the adrenocortical response to stress: Implications for neuropathology and cognitive deficits in later life

1991 • 365 citations

Common Polymorphisms in the Glucocorticoid Receptor Gene Are Associated with Adrenocortical Responses to Psychosocial Stress

2004 • 346 citations

Modulation of cognition-specific cortical activity by gonadal steroids: A positron-emission tomography study in women

1997 • 325 citations

Single-nucleotide polymorphisms can cause different structural folds of mRNA

1999 • 313 citations

Genotype determining low catechol-O-methyltransferase activity as a risk factor for obsessive-compulsive disorder

1997 • 311 citations

Nongenomic Stimulation of Nitric Oxide Release by Estrogen Is Mediated by Estrogen Receptor α Localized in Caveolae

1999 • 304 citations

Characterization and Implications of Estrogenic Down-Regulation of Human Catechol-O-Methyltransferase Gene Transcription

1999 • 297 citations

Functional promoter and polyadenylation site mapping of the human serotonin (5-HT) transporter gene

1995 • 294 citations

Increased anxiety and synaptic plasticity in estrogen receptor β-deficient mice

2001 • 274 citations

Effect of the androgen receptor CAG repeat polymorphism on transcriptional activity: specificity in prostate and non-prostate cell lines

2000 • 266 citations

Genetic Variation in Susceptibility to Endocrine Disruption by Estrogen in Mice

1999 • 263 citations

Prefrontal cortex as the site of estrogen's effect on cognition

2001 • 241 citations

Estrogen-induced changes in place and response learning in young adult female rats.

2002 • 241 citations

Role of estrogen in balancing contributions from multiple memory systems

2004 • 221 citations

Prospective assessment of menstrually related mood disorders

1984 • 220 citations

17β-Estradiol-induced antidepressant-like effect in the Forced Swim Test is absent in estrogen receptor-β knockout (BERKO) mice

2005 • 185 citations

Glucocorticoid Sensitivity Is Determined by a Specific Glucocorticoid Receptor Haplotype

2004 • 180 citations

Antidepressant effects of ERβ-selective estrogen receptor modulators in the forced swim test

2004 • 170 citations

Human catechol-O-methyltransferase down-regulation by estradiol

2003 • 158 citations

Longitudinal Population-Based Twin Study of Retrospectively Reported Premenstrual Symptoms and Lifetime Major Depression

1998 • 139 citations

How Strong Is the Association Between CAG and GGN Repeat Length Polymorphisms in the Androgen Receptor Gene and Prostate Cancer Risk?

2004 • 136 citations

Genetic polymorphisms in the estrogen receptor alpha gene and risk of breast cancer: results from the Shanghai Breast Cancer Study.

2003 • 128 citations

Gonadal steroid regulation of mood: The lessons of premenstrual syndrome☆

2006 • 120 citations

GENECOUNTING: haplotype analysis with missing genotypes

2002 • 117 citations

Genetic contributions to generalized arousal of brain and behavior

2003 • 105 citations

Genetic and environmental factors in the aetiology of menstrual, premenstrual and neurotic symptoms: a population-based twin study

1992 • 103 citations

The Premenstrual Syndrome: A Twin Study

1993 • 101 citations

Presence of Multiple Functional Polyadenylation Signals and a Single Nucleotide Polymorphism in the 3′ Untranslated Region of the Human Serotonin Transporter Gene

1999 • 95 citations

Progesterone receptor gene polymorphism is associated with decreased risk for breast cancer by age 50.

2000 • 85 citations

Synergistic Activation of the Serotonin-1A Receptor by Nuclear Factor-κB and Estrogen

2001 • 68 citations

Operationalizing DSM-IV criteria for PMDD: selecting symptomatic and asymptomatic cycles for research

2002 • 64 citations

Estrogen-induced changes in place and response learning in young adult female rats.

2002 • 63 citations

Haplotypes and the systematic analysis of genetic variation in genes and genomes

2003 • 59 citations

The Premenstrual Syndrome

1992 • 39 citations

Firstborn adolescent daughters and mothers with and without premenstrual syndrome: A comparison

1991 • 36 citations

Serotonin transporter gene polymorphisms and platelet [3H] paroxetine binding in premenstrual dysphoria

2003 • 35 citations

Catechol-O-methyltransferase Gene Polymorphisms in Benign Prostatic Hyperplasia and Sporadic Prostate Cancer

2006 • 34 citations

Catechol-O-methyltransferase Val 108/158 Met polymorphism in premenopausal breast cancer patients

2004 • 31 citations

Estrogen to Antiestrogen with a Single Methylene Group Resulting in an Unusual Steroidal Selective Estrogen Receptor Modulator

2004 • 17 citations

Investigation of transcription factor AP-2beta genotype in women with premenstrual dysphoric disorder

2004 • 12 citations

Genotype modulates the aggression-promoting quality of progesterone in pregnant mice

1988 • 12 citations

Strain differences in tamoxifen sensitivity ofSprague-Dawley and Fischer 344 rats

2002 • 12 citations

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