Interaction of Mammalian Splicing Factor SF3a with U2 snRNP and Relation of Its 60-kD Subunit to Yeast PRP9

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Electroblotting of multiple gels: a simple apparatus without buffer tank for rapid transfer of proteins from polycrylamide to nitrocellulose

1984 • 2,553 citations

U2 as well as U1 small nuclear ribonucleoproteins are involved in premessenger RNA splicing

1985 • 568 citations

Interactions between small nuclear ribonucleoprotein particles in formation of spliceosomes

1987 • 530 citations

Stepwise assembly of a pre-mRNA splicing complex requires U-snRNPs and specific intron sequences

1985 • 524 citations

Electrophoretic separation of complexes involved in the splicing of precursors to mRNAs

1986 • 490 citations

A multicomponent complex is involved in the splicing of messenger RNA precursors

1985 • 451 citations

Structure of spliceosomal snRNPs and their role in pre-mRNA splicing

1990 • 407 citations

Identification, purification, and biochemical characterization of U2 small nuclear ribonucleoprotein auxiliary factor.

1989 • 375 citations

Protein components specifically associated with prespliceosome and spliceosome complexes.

1992 • 218 citations

The 35-kDa mammalian splicing factor SC35 mediates specific interactions between U1 and U2 small nuclear ribonucleoprotein particles at the 3' splice site.

1992 • 198 citations

Heat shock but not other stress inducers leads to the disruption of a sub-set of snRNPs and inhibition of in vitro splicing in HeLa cells.

1988 • 168 citations

Immunoaffinity purification of a [U4/U6.U5] tri-snRNP from human cells.

1991 • 148 citations

Four yeast spliceosomal proteins (PRP5, PRP9, PRP11, and PRP21) interact to promote U2 snRNP binding to pre-mRNA.

1993 • 142 citations

Separation of splicing factor SF3 into two components and purification of SF3a activity

1993 • 129 citations

Small Nuclear Ribonucleoprotein (RNP) U2 Contains Numerous Additional Proteins and Has a Bipartite RNP Structure Under Splicing Conditions

1993 • 117 citations

Presplicing complex formation requires two proteins and U2 snRNP.

1988 • 117 citations

Probing the structure and function of U2 snRNP with antisense oligonucleotides made of 2′-OMe RNA

1989 • 115 citations

The yeast PRP6 gene encodes a U4/U6 small nuclear ribonucleoprotein particle (snRNP) protein, and the PRP9 gene encodes a protein required for U2 snRNP binding.

1990 • 106 citations

Evidence for three distinct D proteins, which react differentially with anti-Sm autoantibodies, in the cores of the major snRNPs U1, U2, U4/U6 and U5

1990 • 105 citations

Three protein factors (SF1, SF3 and U2AF) function in pre-splicing complex formation in addition to snRNPs.

1991 • 104 citations

RNA11 protein is associated with the yeast spliceosome and is localized in the periphery of the cell nucleus.

1988 • 102 citations

Correspondence Between a Mammalian Spliceosome Component and an Essential Yeast Splicing Factor

1993 • 81 citations

Interaction Between PRP11 and SPP91 Yeast Splicing Factors and Characterization of a PRP9-PRP11-SPP91 Complex

1993 • 73 citations

Purification of small nuclear ribonucleoprotein particles with antibodies against modified nucleosides of small nuclear RNAs

1990 • 68 citations

Evidence that the 60-kDa protein of 17S U2 small nuclear ribonucleoprotein is immunologically and functionally related to the yeast PRP9 splicing factor and is required for the efficient formation of prespliceosomes.

1993 • 62 citations

A splicing factor that is inactivated during in vivo heat shock is functionally equivalent to the [U4/U6.U5] triple snRNP-specific proteins.

1992 • 55 citations

Interactions between PRP9 and SPP91 splicing factors identify a protein complex required in prespliceosome assembly.

1993 • 52 citations

A novel gene, spp91-1, suppresses the splicing defect and the pre-mRNA nuclear export in the prp9-1 mutant.

1992 • 46 citations

Inactivation of splicing factors in HeLa cells subjected to heat shock

1990 • 35 citations

The U2 small nuclear ribonucleoprotein particle associates with nuclear factors in a pre-mRNA independent reaction.

1991 • 11 citations

Purification of small nuclear ribonucleoprotein particles active in RNA processing

1990 • 7 citations