P-glycoprotein and multidrug resistance-associated protein are involved in the regulation of extracellular levels of the major antiepileptic drug carbamazepine in the brain

MDR1 Gene Expression in Brain of Patients with Medically Intractable Epilepsy

1995 • 525 citations

Blood-brain barrier biology and methodology

1999 • 436 citations

P-glycoprotein: a defense mechanism limiting oral bioavailability and CNS accumulation of drugs

2000 • 382 citations

Interactions of the Human Multidrug Resistance Proteins MRP1 and MRP2 with Organic Anions

2000 • 313 citations

Xenobiotic Transport across Isolated Brain Microvessels Studied by Confocal Microscopy

2000 • 310 citations

Mrp1 Multidrug Resistance‐Associated Protein and P‐Glycoprotein Expression in Rat Brain Microvessel Endothelial Cells

1998 • 265 citations

Animal models of intractable epilepsy

1997 • 245 citations

Expression of various multidrug resistance-associated protein (MRP) homologues in brain microvessel endothelial cells

2000 • 233 citations

Expression of Multidrug Resistance-Associated Protein (MRP) in Brain Microvessel Endothelial Cells

1998 • 202 citations

ABC drug transporters: hereditary polymorphisms and pharmacological impact in MDR1, MRP1 and MRP2

2001 • 197 citations

Substrate recognition by P-glycoprotein and the multidrug resistance-associated protein MRP1: a comparison

2000 • 144 citations

Determinants of passive drug entry into the central nervous system.

2000 • 127 citations

Over-expression of Pglycoprotein in malformations of cortical development

1999 • 118 citations

Brain drug delivery, drug metabolism, and multidrug resistance at the choroid plexus

2000 • 115 citations

Multidrug-Resistance Transporters

2002 • 106 citations

Distribution of valproate across the interface between blood and cerebrospinal fluid

1978 • 86 citations

Multidrug resistance-associated protein is involved in the regulation of extracellular levels of phenytoin in the brain

2001 • 72 citations

Drug Transport in the Mammalian Central Nervous System: Multiple Complex Systems

2000 • 54 citations

Probenecid-inhibitable efflux transport of valproic acid in the brain parenchymal cells of rabbits: a microdialysis study

2000 • 47 citations