Transcription analysis and sequence of the putative murine cytomegalovirus DNA polymerase gene

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Improved tools for biological sequence comparison.

1988 • 11,455 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing

1980 • 3,476 citations

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

1984 • 3,334 citations

DNA sequence and expression of the B95-8 Epstein—Barr virus genome

1984 • 2,039 citations

The “initiator” as a transcription control element

1989 • 1,597 citations

Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl)guanine

1977 • 1,565 citations

Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

1986 • 1,424 citations

Analysis of the Protein-Coding Content of the Sequence of Human Cytomegalovirus Strain AD169

1990 • 1,280 citations

A rapid single-stranded cloning strategy for producing a sequential series of overlapping clones for use in DNA sequencing: Application to sequencing the corn mitochondrial 18 S rDNA

1985 • 1,051 citations

Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers.

1989 • 1,046 citations

Promoter Sequences of Eukaryotic Protein-Coding Genes

1980 • 971 citations

Thymidine kinase from herpes simplex virus phosphorylates the new antiviral compound, 9-(2-hydroxyethoxymethyl)guanine.

1978 • 560 citations

A simple, rapid method for the purification of poly A+ RNA.

1988 • 382 citations

Antiviral Activity and Mechanism of Action of Ganciclovir

1988 • 354 citations

Inhibition of herpes simplex virus-induced DNA polymerase activity and viral DNA replication by 9-(2-hydroxyethoxymethyl)guanine and its triphosphate

1979 • 348 citations

Identification of the human cytomegalovirus glycoprotein B gene and induction of neutralizing antibodies via its expression in recombinant vaccinia virus.

1986 • 334 citations

Two distinct loci confer resistance to acycloguanosine in herpes simplex virus type 1.

1980 • 285 citations

A cellular protein, activating transcription factor, activates transcription of multiple E1A-inducible adenovirus early promoters.

1987 • 284 citations

Growth Inhibition by Acycloguanosine of Herpesviruses Isolated from Human Infections

1979 • 272 citations

Phosphorylation of acyclovir (acycloguanosine) monophosphate by GMP kinase.

1980 • 269 citations

Related functional domains in virus DNA polymerases.

1987 • 243 citations

DNA sequence of the region in the genome of herpes simplex virus type 1 containing the genes for DNA polymerase and the major DNA binding protein

1985 • 213 citations

A cellular transcription factor E4F1 interacts with an E1a-inducible enhancer and mediates constitutive enhancer function in vitro.

1987 • 208 citations

Nucleotide sequence specifying the glycoprotein gene, gB, of herpes simplex virus type 1

1984 • 192 citations

Identification of amino acids in herpes simplex virus DNA polymerase involved in substrate and drug recognition.

1988 • 190 citations

The murine cytomegalovirus as a model for the study of viral pathogenesis and persistent infections

1979 • 175 citations

Sequence and mapping analyses of the herpes simplex virus DNA polymerase gene predict a C-terminal substrate binding domain.

1985 • 172 citations

Sequence and transcription analysis of the human cytomegalovirus DNA polymerase gene

1987 • 170 citations

Latent Infection and the Elusive Cytomegalovirus

1983 • 161 citations

Stimulation of Cellular Thymidine Kinases by Human Cytomegalovirus

1977 • 141 citations

Molecular cloning and physical mapping of murine cytomegalovirus DNA

1983 • 134 citations

Activity of 9-(1,3-dihydroxy-2-propoxymethyl)guanine compared with that of acyclovir against human, monkey, and rodent cytomegaloviruses

1985 • 127 citations

Epstein-Barr virus genome may encode a protein showing significant amino acid and predicted secondary structure homology with glycoprotein B of herpes simplex virus 1

1985 • 123 citations

Inhibition of cellular DNA polymerase alpha and human cytomegalovirus-induced DNA polymerase by the triphosphates of 9-(2-hydroxyethoxymethyl)guanine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine

1985 • 121 citations

Identification of a factor in HeLa cells specific for an upstream transcriptional control sequence of an EIA-inducible adenovirus promoter and its relative abundance in infected and uninfected cells.

1986 • 109 citations

Construction of a cloned library of the EcoRI fragments from the human cytomegalovirus genome (strain AD169)

1982 • 99 citations

Acyclovir-resistant mutants of herpes simplex virus type 1 express altered DNA polymerase or reduced acyclovir phosphorylating activities

1981 • 92 citations

Inhibition of cellular alpha and virally induced deoxyribonucleic acid polymerases by the triphosphate of acyclovir

1980 • 90 citations

Cleavage maps for human cytomegalovirus DNA strain AD169 for restriction endonucleases EcoRI, BglII, and HindIII

1982 • 77 citations

Molecular cloning and restriction endonuclease mapping of the murine cytomegalovirus genome (Smith strain)

1983 • 76 citations

2.2-kilobase class of early transcripts encoded by cell-related sequences in human cytomegalovirus strain AD169

1986 • 74 citations

Large-scale rearrangement of homologous regions in the genomes of HCMV and EBV

1987 • 71 citations

Thymidine-kinase in cytomegalovirus infected cells

1976 • 70 citations

A single-base change within the DNA polymerase locus of herpes simplex virus type 2 can confer resistance to aphidicolin

1987 • 69 citations

Isolation and characterization of herpes simplex virus mutants containing engineered mutations at the DNA polymerase locus

1990 • 69 citations

EivF, a factor required for transcription of the adenovirus EIV promoter, binds to an element involved in EIa-dependent activation and cAMP induction.

1988 • 67 citations

Antiviral Drug Development

1988 • 62 citations

Cytomegalovirus and Other Herpesviruses

1982 • 60 citations

Genomic localization, sequence analysis, and transcription of the putative human cytomegalovirus DNA polymerase gene

1987 • 59 citations

Site-specific mutagenesis of a highly conserved region of the herpes simplex virus type 1 DNA polymerase gene

1990 • 49 citations

Mutations in the herpes simplex virus DNA polymerase gene conferring hypersensitivity to aphidicolin

1983 • 49 citations

The Herpes Simplex Virus Type 1 DNA Polymerase Gene: Site of Phosphonoacetic Acid Resistance Mutation in Strain Angelotti is Highly Conserved

1987 • 48 citations

Human Cytomegalovirus Early Gene Expression

1990 • 45 citations

Thymidine kinase not required for antiviral activity of acyclovir against mouse cytomegalovirus

1981 • 43 citations

Thymidine kinase activity in mouse 3T3 cells infected by murine cytomegalovirus (MCV)

1977 • 42 citations

Human cytomegalovirus-induced DNA polymerase and its interaction with the triphosphates of 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-methyluracil, -5-iodocytosine, and -5-methylcytosine

1985 • 40 citations

Single Mutations at Many Sites within the DNA Polymerase Locus of Herpes Simplex Viruses Can Confer Hypersensitivity to Aphidicolin and Resistance to Phosphonoacetic Acid

1984 • 38 citations

Effects of Certain Nucleoside Analogues on Human Cytomegalovirus Replication in vitro

1984 • 35 citations

Structure-function studies of the herpes simplex virus type 1 DNA polymerase

1990 • 34 citations

Analysis in vitro of two biologically distinct strains of murine cytomegalovirus

1988 • 31 citations

In vitro mutagenesis of the herpes simplex virus type 1 DNA polymerase gene results in altered drug sensitivity of the enzyme

1989 • 30 citations

Inhibition of murine cytomegalovirus lung infection and interstitial pneumonitis by acyclovir and 9-(1,3-dihydroxy-2-propoxymethyl)guanine

1985 • 28 citations

9-(1-3-Dihydroxy-2-propoxymethyl)guanine prevents death but not immunity in murine cytomegalovirus-infected normal and immunosuppressed BALB/c mice

1987 • 27 citations

Restoration of Wild-type Pathogenicity to an Attenuated DNA Polymerase Mutant of Herpes Simplex Virus Type 1

1986 • 27 citations

Replication of Mouse Cytomegalovirus in Thymidine Kinase‐Deficient Mouse Cells

1978 • 22 citations

Interstitial Pneumonitis During Murine Cytomegalovirus Infection and Graft-Versus-Host Reaction: Effect of Ganciclovir Therapy

1988 • 22 citations

Genetic analysis of the susceptibility of mouse cytomegalovirus to acyclovir

1985 • 17 citations

Efficacy of acyclovir against mouse cytomegalovirus in vivo

1981 • 14 citations

Aerosol Administration of Antiviral Agents to Treat Lung Infection Due to Murine Cytomegalovirus

1988 • 11 citations

Animal Models as Assay Systems for the Development of Antivirals

1988 • 8 citations

Successful treatment of murine cytomegalovirus disease does not prevent latent virus infection.

1986 • 8 citations

Workshop IV: Cytomegalovirus and Other Herpes Viruses

1988 • 6 citations

Successful treatment of murine cytomegalovirus disease does not prevent latent virus infection.

1986 • 3 citations