Opposing regulatory effects of protein kinase C on the cAMP cascade in human HL-60 promyelocytic leukemia cells

A highly sensitive adenylate cyclase assay

1974 • 4,213 citations

Protein kinase C and lipid signaling for sustained cellular responses

1995 • 2,527 citations

Diversity of G Proteins in Signal Transduction

1991 • 1,990 citations

Consensus sequences as substrate specificity determinants for protein kinases and protein phosphatases

1991 • 1,327 citations

Complexity and Diversity of Mammalian Adenylyl Cyclases

1996 • 857 citations

Cross-talk between cellular signalling pathways suggested by phorbol-ester-induced adenylate cyclase phosphorylation

1987 • 524 citations

G protein—coupled receptor kinases

1993 • 434 citations

Cloning of a novel human prostaglandin receptor with characteristics of the pharmacologically defined EP2 subtype.

1994 • 384 citations

‘Crosstalk’: a pivotal role for protein kinase C in modulating relationships between signal transduction pathways

1991 • 328 citations

Differential activation of adenylyl cyclase by protein kinase C isoenzymes

1994 • 218 citations

Type-specific stimulation of adenylylcyclase by protein kinase C.

1993 • 187 citations

Phorbol ester-induced stimulation and phosphorylation of adenylyl cyclase 2.

1994 • 159 citations

Molecular cloning and characterization of the type VII isoform of mammalian adenylyl cyclase expressed widely in mouse tissues and in S49 mouse lymphoma cells.

1994 • 158 citations

G-Protein-coupled receptors in HL-60 human leukemia cells

1996 • 99 citations

Desensitization of the turkey erythrocyte beta-adrenergic receptor in a cell-free system. Evidence that multiple protein kinases can phosphorylate and desensitize the receptor.

1985 • 97 citations

Multiple signaling pathways of histamine H2 receptors

1989 • 88 citations

cAMP-dependent protein kinase and protein kinase C consensus site mutations of the beta-adrenergic receptor. Effect on desensitization and stimulation of adenylylcyclase.

1994 • 87 citations

Differential Translocation of Protein Kinase C ε during HeLa Cell Adhesion to a Gelatin Substratum

1996 • 87 citations

Regulation of release of hepatocyte growth factor from human promyelocytic leukemia cells, HL-60, by 1,25-dihydroxyvitamin D3, 12-O- tetradecanoylphorbol 13-acetate, and dibutyryl cyclic adenosine monophosphate

1993 • 84 citations

n 6 and n 3 Polyunsaturated fatty acids stimulate translocation of protein kinase Cα, -βI, -βII and -ε and enhance agonist-induced NADPH oxidase in macrophages

1997 • 53 citations

Redistribution of Protein Kinase C Isoforms in Human Neutrophils Stimulated by Formyl Peptides and Phorbol-Myristate Acetate

1995 • 53 citations

Dissociation of Mitogen-activated Protein Kinase Activation from the Oxidative Burst in Differentiated HL-60 Cells and Human Neutrophils

1995 • 48 citations

Protein kinase C stimulates adenylate cyclase activity in prolactin‐secreting rat adenoma (GH₄C₁) pituicytes by inactivating the inhibitory GTP‐binding protein G_i

1989 • 47 citations

Phorbol esters inhibit adenylate cyclase activity in cultured collecting tubular cells

1988 • 45 citations

Translocation of Protein Kinase C Isoforms in Rat Neutrophils

1997 • 40 citations

Histamine-induced differentiation of HL-60 cells

1992 • 37 citations

Dual Action of cAMP-Dependent Protein Kinase on Granulocyte Movement

1997 • 36 citations

Rapid transcriptional down-regulation of c-myc expression during cyclic adenosine monophosphate-promoted differentiation of leukemic cells.

1987 • 35 citations

Conditional activation of cAMP signal transduction by protein kinase C. The effect of phorbol esters on adenylyl cyclase in permeabilized and intact cells.

1994 • 31 citations

Modulation of Gs activity by phorbol myristate acetate in rat hepatocytes

1991 • 20 citations

Interaction between the two signal transduction systems of the histamine H2 receptor: desensitizing and sensitizing effects of histamine stimulation on histamine-dependent cAMP production in Chinese hamster ovary cells

1996 • 20 citations

Phorbol ester-mediated desensitization of histamine H1 receptors on a cultured smooth muscle cell line

1988 • 19 citations

The Human Promyelocytic Leukemia Cell (HL-60 Cell) β-Adrenergic Receptor

1988 • 19 citations

Granulocyte colony-stimulating factor-induced activation of protein kinase-C in myeloid cells

1997 • 18 citations

pp75: A novel tyrosine-phosphorylated protein that heralds differentiation of HL-60 cells

1991 • 17 citations

Stimulation of Adenylyl Cyclase Mediated by Phospholipase C‐Linked M₃ Muscarinic Receptor in Human Neuroblastoma SK‐N‐BE(2)C Cells

1995 • 15 citations

Synergistic activation of adenylyl cyclase is dependent upon phospholipase C-mediated processes in human neuroblastoma SK-N-BE(2)C cells

1996 • 14 citations

Regulation of cAMP levels by protein kinase C in C6 rat glioma cells

1990 • 12 citations

Modulation of responsiveness to cAMP stimulating agonists by phorbol ester in fetal rat osteoblasts

1991 • 10 citations

Phorbol ester induces desensitization of PTH-stimulated cyclic AMP production by decreasing the PTH receptor binding in UMR-106 cells

1991 • 5 citations

Pharmacological Modulation of c-fos mRNA Expression in the HL60 and U937 Cell Lines

1993 • 3 citations

Down-regulation and differential restoration of cAMP responses upon transient phorbol ester treatment of primary osteoblastic cells

1995 • 3 citations

Deleted Work

1955 • 0 citations