Interaction between the two signal transduction systems of the histamine H2 receptor: desensitizing and sensitizing effects of histamine stimulation on histamine-dependent cAMP production in Chinese hamster ovary cells

The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C

1991 • 2,499 citations

An ultrasensitive method for the simultaneous determination of cyclic AMP and cyclic GMP in small-volume samples from blood and tissue

1977 • 679 citations

Enhancement of adenylate cyclase activity in S49 lymphoma cells by phorbol esters. Putative effect of C kinase on alpha s-GTP-catalytic subunit interaction.

1985 • 239 citations

Stimulation of specific types of Gs-stimulated adenylyl cyclases by phorbol ester treatment.

1993 • 235 citations

Molecular cloning of the human histamine H2 receptor

1991 • 183 citations

Platelet-activating factor (PAF) receptor in rat brain: PAF mobilizes intracellular Ca2+ in hippocampal neurons

1992 • 175 citations

Specific binding of 3H-tiotidine to histamine H2 receptors in guinea pig cerebral cortex

1983 • 159 citations

Cloning and tissue expression of a rat histamine H2-receptor gene

1991 • 99 citations

Multiple signaling pathways of histamine H2 receptors

1989 • 88 citations

cAMP-dependent protein kinase and protein kinase C consensus site mutations of the beta-adrenergic receptor. Effect on desensitization and stimulation of adenylylcyclase.

1994 • 87 citations

Structural and functional analysis of the canine histamine H2 receptor by site-directed mutagenesis: N-glycosylation is not vital for its action

1995 • 72 citations

Characterization of H2 histamine receptor: linkage to both adenylate cyclase and [Ca2+]i signaling systems

1992 • 64 citations

Modulation of cyclic AMP accumulation in GH3 cells by a phorbol ester and thyroliberin

1985 • 64 citations

Synergism between histamine H1- and H2-receptors in the cAMP response in guinea pig brain slices: effects of phorbol esters and calcium.

1988 • 59 citations

Effects of phorbol esters on α1-adrenergic-mediated and glucagon-mediated actions in isolated rat hepatocytes

1985 • 55 citations

Phorbol Esters Enhance Neurotransmitter‐Stimulated Cyclic AMP Production in Rat Brain Slices

1986 • 52 citations

Multiple effects of phorbol ester on secretory activity in rabbit gastric glands and parietal cells

1987 • 37 citations

Autoregulation of muscarinic and gastrin receptors on gastric parietal cells

1989 • 32 citations

Conditional activation of cAMP signal transduction by protein kinase C. The effect of phorbol esters on adenylyl cyclase in permeabilized and intact cells.

1994 • 31 citations

Desensitization of Canine Histamine H2 Receptor Expressed in Chinese Hamster Ovary Cells

1993 • 28 citations

Inhibition of gastric acid secretion by a phorbol ester: Effect of 12-O-tetradecanoylphorbol-13-acetate on aminopyrine accumulation by rat parietal cells

1984 • 23 citations

Sites of action of protein kinase C on secretory activity in rat parietal cells

1989 • 15 citations

Indirect inhibition by bradykinin of cyclic AMP generation in isolated rat glomeruli and mesangial cells.

1993 • 13 citations